Original Investigation

Cognitive Behavior vs Bright Light Therapy for Insomnia in Women Undergoing Chemotherapy for Breast Cancer

JAMA Network Open 10.1001/jamanetworkopen.2026.30320

August 27, 2026 at 11:00 AM EDT

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In the SleepCARE RCT of CBT-I and BLT administered for 6 weeks to women receiving chemotherapy for breast cancer, CBT-I improved insomnia but not fatigue compared with SHE or BLT. BLT did not produce greater improvements in fatigue or insomnia symptoms compared with non-BLT treatment. The study findings indicate that brief CBT-I, but not BLT, may reduce insomnia symptoms among women receiving chemotherapy for breast cancer.

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Corresponding Author: Joshua F. Wiley, PhD, School of Psychological Sciences, Turner Institute for Brain and Mental Health, 270 Ferntree Gully Rd, Monash University, Melbourne, VIC 3800, Australia (joshua.wiley@monash.edu).

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