Original Investigation

Physical Fitness and All-Cause Mortality in Older Adults

JAMA Network Open 10.1001/jamanetworkopen.2026.28227

August 10, 2026 at 11:00 AM EDT

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In this cohort study of older adults, objectively measured physical fitness—particularly balance and agility, lower-body strength, and cardiorespiratory fitness—was associated with lower all-cause mortality in a graded manner. These findings suggest that integrating objective fitness assessments into routine practice may refine risk stratification and guide function-oriented interventions in older adults.

Corresponding Authors: Li-Lin Liang, PhD, Institute of Public Health, College of Medicine, National Yang Ming Chiao Tung University, No. 155, Sec 2, Linong Street, Beitou District, Taipei, 11221, Taiwan (liang.lilin@nycu.edu.tw); Chen-Te Hsu, PhD, MPH, Department of Sport Management, National Taiwan University of Sport, No. 16, Sec. 1, Shuangshi Road, North District, Taichung City 404401, Taiwan (cthsu@ntus.edu.tw).

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