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Cost-Effectiveness of Endovascular vs Open Surgery for Chronic Limb-Threatening Ischemia

JAMA Network Open 10.1001/jamanetworkopen.2026.27335

August 04, 2026 at 11:00 AM EDT

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This cost-effectiveness study found that bypass surgery was more cost-effective in most probabilistic simulations; however, uncertainty remained, highlighting the need for future research to identify subgroups in whom each approach may be cost-effective.

Corresponding Author: Zafar Zafari, PhD, University of Maryland Institute for Health Computing, 6116 Executive Blvd, Bethesda, MD 20852 (zzafari@rx.umaryland.edu).

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