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Diagnostic Stewardship of Respiratory Cultures Using Clinical Decision Support in the PICU

JAMA Network Open 10.1001/jamanetworkopen.2026.26547

July 31, 2026 at 11:00 AM EDT

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In this multicenter cohort study, diagnostic stewardship of EACs using clinical decision support led by multidisciplinary teams was associated with reduced EAC use in the PICU without safety concerns. Future work will determine optimal implementation strategies, assess sustainability and the cost impact of EAC stewardship.

Corresponding Author: Anna C. Sick-Samuels, MD, MPH, Department of Pediatrics, Johns Hopkins University School of Medicine, 200 N Wolfe St, Ste 3093, Baltimore, MD 21287 (asick1@jhmi.edu).

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