Original Investigation

Cervical Cancer Screening With Human Papillomavirus Self-Collection Testing in an Opioid Treatment Program

JAMA Network Open 10.1001/jamanetworkopen.2026.25993

July 29, 2026 at 11:00 AM EDT

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Can human papillomavirus (HPV) self-collection testing for cervical cancer screening be offered in the setting of an opioid treatment program (OTP)? In this cohort study of 194 patients in an OTP, HPV self-collection testing for cervical cancer screening was implemented into the annual wellness visit. There were high eligibility and uptake rates: of the patients assessed for screening, 89.7% were eligible and 90.8% completed specimen self-collection. The findings suggest that incorporating cervical cancer screening using HPV self-collection testing was feasible and highly accepted by patients in an OTP.

Corresponding Author: Elizabeth M. Swisher, MD, Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, 1959 NE Pacific St, Box 356460, Seattle, WA 98195-6460 (swishere@uw.edu).

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