Maternal Intellectual and Developmental Disabilities and Infant Outcomes

How do birth and infant outcomes differ between women with and women without intellectual and developmental disabilities (IDDs)?In a cohort study comprising 6.4 million California births (2007-2021), infants of mothers with IDDs had higher risks of neonatal intensive care unit admission, preterm birth, and small-for-gestational-age birth; risks were highest for maternal chromosomal differences or intellectual disability. Preexisting hypertension, epilepsy, and mental health conditions were associated with a substantial portion of these risks.This study suggests that maternal IDDs are associated with adverse infant outcomes and that managing chronic and neuropsychiatric conditions may reduce these disparities.

Corresponding Author: Catherine Psaras, PhD, Department of Pediatrics, University of California, 7910 Frost St, Ste 370, San Diego, CA 92123 (cpsaras@health.ucsd.edu).

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