Rheumatoid Arthritis in Adults

Rheumatoid arthritis is a chronic autoimmune disease that causes joint destruction. First-line initial therapy is methotrexate, with consideration of glucocorticoids as additive therapy. For patients who do not achieve remission with this initial treatment, adding biological DMARDs or JAK inhibitors increases overall remission or low disease activity rates to 80%.

Corresponding Author: Josef S. Smolen, MD, Division of Rheumatology, Department of Medicine 3, Medical University of Vienna, Spitalgasse 23, 1090 Vienna, Austria (josef.smolen@meduniwien.ac.at).

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