Original Investigation

Adoption of Adjunctive Azithromycin for Unscheduled Cesarean Delivery and Postpartum Infections

JAMA 10.1001/jama.2026.15010

September 14, 2026 at 11:00 AM EDT

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After publication of the trial evidence in 2016, azithromycin use for pregnant persons undergoing unscheduled cesarean delivery increased and postpartum infection rates decreased in the US.

Corresponding Author: Taylor S. Freret, MD, EdM, Department of Obstetrics and Gynecology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02115 (tfreret@bidmc.harvard.edu).

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