Original Investigation

Oxygen vs Air at Birth for Moderate- to Late-Preterm Infants

JAMA 10.1001/jama.2026.14201

September 09, 2026 at 11:00 AM EDT

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For neonates born at 32 to 35 weeks’ gestation, there was no difference between those commencing resuscitation with Fio 0.30 vs F2 0.21 in the proportion still receiving respiratory support when leaving the delivery room.io2

Corresponding Author: Louise S. Owen, MD, Newborn Research, Level 7, Royal Women’s Hospital, 20 Flemington Rd, Parkville, Melbourne, VIC 3052, Australia (louise.owen@thewomens.org.au).

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