Study Suggests Home-Based Exercise Beneficial for Patients With Alzheimer Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 15, 2013   JAMA Internal Medicine Study Highlights   Study Suggests Home-Based Exercise Beneficial for Patients With Alzheimer Disease   A randomized controlled trial by Kaisu H. Pitkala, M.D., Ph.D., of the University of Helsinki, Finland, and colleagues suggests an intensive and long-term exercise program has beneficial…

Study Examines Influence of Providing Fee Data on Laboratory Test Ordering

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 15, 2013   JAMA Internal Medicine Study Highlights   Study Examines Influence of Providing Fee Data on Laboratory Test Ordering   A study by Leonard S. Feldman, M.D., and colleagues at The Johns Hopkins University School of Medicine, Baltimore, examined if the number of laboratory tests ordered…

Study Examines Downstream Outcomes Following Prostate-Specific Antigen Screening in Older Men

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 15, 2013   JAMA Internal Medicine Study Highlights   Study Examines Downstream Outcomes Following Prostate-Specific Antigen Screening in Older Men   A study by Louise C. Walter, M.D., of San Francisco Veterans Affairs Medical Center, California, and colleagues sought to quantify 5-year downstream outcomes following an abnormal…

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Study Suggests Glucocerebrosidase Gene Mutations Are Risk Factor For Dementia With Lewy Bodies

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 15, 2013   JAMA Neurology Study Highlights   Study Suggests Glucocerebrosidase Gene Mutations Are Risk Factor For Dementia With Lewy Bodies   A study by Michael A. Nalls, Ph.D., of the National Institutes of Health, Bethesda, and colleagues suggests mutations in glucocerebrosidase (GBA1) are a risk factor…

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Study Examines Relationship Between Pregnant Women’s Hostile Attributes and Early Child Maltreatment

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 15, 2013   JAMA Pediatrics Study Highlights   Study Examines Relationship Between Pregnant Women’s Hostile Attributes and Early Child Maltreatment   A prospective longitudinal study by Lisa J. Berlin, Ph.D., of the University of Maryland School of Social Work, Baltimore, and colleagues examined pregnant women’s hostile attributions…

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Study Suggests Strict School Meal Standards Associated With Improved Weight Status Among Students

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 8, 2013 Media Advisory: To contact study author Daniel R. Taber, Ph.D., call Sherri McGinnis Gonzalez at 312-996-8277 or email smcginn@uic.edu. To contact editorial author Marion Nestle, Ph.D., M.P.H., call Courtney Bowe at 212-998-6797 or email courtney.bowe@nyu.edu. CHICAGO – A study suggests that states with stricter school…

Systematic Review Examines Electronic Media-Based Behavior Change in Youth

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 8, 2013 JAMA Pediatrics Study Highlights A systematic review by Kimberly Hieftje, Ph.D., Yale University School of Medicine, New Haven, and colleagues examines the type and quality of studies evaluating the effects of electronic media-based interventions that focused on promoting health and safety behavior change in youth….

Study Suggests Interventions Are Needed to Sustain Tobacco Abstinence After Release From Prison

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 8, 2013 JAMA Internal Medicine Study Highlights A study by Jennifer G. Clarke, M.D., M.P.H., of Memorial Hospital of Rhode Island, Pawtucket, and colleagues suggests that behavioral intervention provided prior to release from prison improves tobacco abstinence in the community. (Online First)   A total of 262…

Study Suggests Elder Abuse Associated With Increased Rates of Hospitalization

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 8, 2013 JAMA Internal Medicine Study Highlights A study by XinQi Dong, M.D., M.P.H., of Rush University Medical Center, and Melissa A. Simon, M.D., M.P.H., of Northwestern University Medical Center, Chicago, suggests elder abuse is associated with increased rates of hospitalization. (Online First)   Of the 6674…

Research Letter, Viewpoint, Invited Commentary Examine Cervical Cancer Screening Intervals

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 8, 2013 JAMA Internal Medicine Study Highlights A research letter by Zahava Berkowitz, M.S.P.H., M.Sc., of the Centers for Disease Control and Prevention, and colleagues found that most of the 2,087 primary care clinicians surveyed recommended Papanicolaou (pap) tests sooner than recommended by guidelines after co-testing for…

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Study Examines Disease Progression After Regional Therapy for In-Transit Melanoma

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, APRIL 3, 2013 JAMA Surgery Study Highlights A study by Michael E. Lidsky, M.D., and colleagues at Duke University Medical Center, Durham, suggests that patient, clinical, and procedural factors are unreliable predictors of in-field progressive disease after regional therapy in patients with in-transit melanoma. (Online First)   Using…

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Study Suggests Psychological Distress Higher Among Parents of Children With Advanced Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 1, 2013 JAMA Pediatrics Study Highlights A study by Abby R. Rosenberg, M.D., M.S., of Seattle Children’s Hospital, Seattle, and colleagues suggests that high to severe levels of psychological distress (PD) are common among parents of a child with advanced cancer. (Online First)   The cohort study…

Study Examines Lack of Communication Between Health Care Staff, Elderly Patients and Their Families About Advanced Care Plan

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 1, 2013 JAMA Internal Medicine Study Highlights A study by Daren K. Heyland, M.D., M.Sc., of Kingston General Hospital, Ontario, Canada and colleagues examined elderly patients’ advance care planning activities before hospitalization and preferences for care from the perspectives of patients and family members. (Online First)  …

Increased Risk of Venous Thromboembolism May Be Associated With Glucocorticoid Use

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 1, 2013 JAMA Internal Medicine Study Highlights A study by Sigrun A. Johannesdottir, B.Sc., of Aarhus University Hospital, the Netherlands, and colleagues suggests that the risk of venous thromboembolism (VTE, blood clot) was increased in users of glucocorticoids, anti-inflammatory drugs widely used for conditions such as chronic…

Clinical Trial Finds Improvement in Cognitive Function But No Difference Between Group’s After Physical, Mental Activity in Older Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, APRIL 1, 2013 Media Advisory: To contact author Deborah E. Barnes, Ph.D., M.P.H., call Juliana Bunim at 415-502-6397 or email Juliana.Bunim@ucsf.edu. To contact commentary author Nicola T. Lautenschlager, M.D., email nicolatl@unimelb.edu.au. CHICAGO – A randomized controlled trial finds that 12 weeks of physical plus mental activity in inactive…

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Study Develops Prediction Model to Help Identify Avoidable 30-Day Hospital Readmissions

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 JAMA Internal Medicine Study Highlights A study by Jacques Donzé, M.D., M.Sc., of Brigham and Women’s Hospital, Boston, and colleagues suggests that a prediction model can identify before discharge the risk of potentially avoidable 30-day readmission in hospitalized patients.   The study at an academic…

Study Examines Effect of 2011 Duty Hour Regulation vs. 2003 Regulations on First-Year Residents Sleep Duration, Trainee Education and Patient Care

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 JAMA Internal Medicine Study Highlights Sanjay V. Desai, M.D., and colleagues of The John Hopkins University, Baltimore, used a crossover study of medical house staff to examine the effects of the 2011 Accreditation Council for Graduate Medical Education duty hour regulations compared with the 2003…

Study Explores Outcomes Associated With Reduced Duty Hours Among First-Year Residents

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 JAMA Internal Medicine Study Highlights A study by Srijan Sen, M.D., Ph.D., of the University of Michigan, Ann Arbor, and colleagues, examined duty hours, hours of sleep, well-being, and reports of medical errors among first-year residents (interns) before and after implementation of the 2011 duty…

Research Letter Examines Overuse of Magnetic Resonance Imaging

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 JAMA Internal Medicine Study Highlights In a research letter, Derek J. Emery, M.D., F.R.C.P.C, of the University of Alberta, Edmonton, Canada, and colleagues examined the appropriateness of requests for outpatient magnetic resonance imaging (MRI) of the lumbar spine and of the head for headache, which…

Study Suggests Teenage Smokers With Higher Genetic Risk Associated With Development of Adult Smoking Problems

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 27, 2013 JAMA Psychiatry Study Highlights A study by Daniel W. Belsky, Ph.D., of the University of North Carolina at Chapel Hill and Duke University Medical Center, Durham, North Carolina, and colleagues sought to examine how genetic risks influence the developmental progression of smoking behavior from initiation…

Study Finds Data on Experience-Related Outcomes Limited in Children’s Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 Media Advisory: To contact study author Jarod P. McAteer, M.D., of Seattle Children’s Hospital call Mary Guiden at 206-987-7334 or email Press@SeattleChildrens.org. CHICAGO – A review of the available medical literature suggests that data on experience-related outcomes in children’s surgery are limited and vary widely…

Mild Cognitive Impairment at Parkinson Disease Diagnosis Associated with Increased Risk for Early Dementia

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 25, 2013 Media Advisory: To contact study author Kenn Freddy Pedersen, M.D., Ph.D., email kenfrp@online.no. To contact editorial author Brian J. Copeland, M.D., call Robert Cahill at 713-500-3030 or email Robert.cahill@uth.tmc.edu. CHICAGO – Mild cognitive impairment at the time of Parkinson disease (PD) diagnosis appears to be…

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Randomized Trial Examines Supplementation in Age-Related Macular Degeneration

EMBARGOED FOR RELEASE: 3 P.M. (CT), THURSDAY, MARCH 21, 2013   JAMA Ophthalmology Study Highlights   A randomized trial by Christin Arnold, Dipl-Troph, of Friedrich Schiller University Jena, Germany, and colleagues found that a supplement containing a fixed combination of lutein, zeaxanthin and omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) during 12 months significantly improved plasma…

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Study Investigates Association Between Race And Use Of Revascularizaton vs Amputation in Lower Extremity Ischemia

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 20, 2013   JAMA Surgery Study Highlights   A study by Tyler S. Durazzo, M.D., and colleagues at the Yale University School of Medicine, New Haven, examined the difference between white and nonwhite patients in the rates of use of amputation or revascularization procedures for treatment of…

Study Examines Laparoscopic Effectiveness in Incisional Hernia Repair

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 20, 2013   JAMA Surgery Study Highlights   A randomized controlled clinical trial by Hasan H. Eker, M.D., of Erasmus Medical Center, Rotterdam, the Netherlands, and colleagues examined laparoscopic versus open ventral incisional hernia repair with regard to postoperative pain and nausea, operative results, perioperative and postoperative…

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Research Letter Suggests Handheld Umbrella Useful for Blocking UV Rays

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, March 20, 2013   JAMA Dermatology Study Highlights   In a research letter, Josette R. McMichael, M.D, of the Emory University School of Medicine, Atlanta, and colleagues examined the amount of UV radiation (UVR) that penetrates a handheld umbrella (HU). (Online First)   The authors collected 23 umbrellas,…

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Advanced Grandparent Age Appears Associated with Increased Autism Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 20, 2013   JAMA Psychiatry Study Highlights   A study by Emma M. Frans, M.Sc., of the Karolinska Institutet, and colleagues suggests that advanced grandparental age is associated with an increased risk of autism.   The authors conducted a study of individuals born in Sweden since 1932…

Study Examines Link Between Maternal Exposure to Childhood Abuse, Autism Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 20, 2013   JAMA Psychiatry Study Highlights   A study by Andrea L. Roberts, Ph.D., of the Harvard School of Public Health, Boston, and colleagues suggests that maternal exposure to childhood abuse is associated with an increased risk for autism in their children. (Online First)   Researchers…

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Study Suggests Nurse Understaffing Associated With NICU Infection Rates

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 18, 2013   JAMA Pediatrics Study Highlights   A study by Jeannette A. Rogowski, Ph.D., of the University of Medicine and Dentistry of New Jersey, Piscataway, and colleagues suggests nurse understaffing in US neonatal intensive care units (NICUs) is associated with higher rates of nosocomial infections among…

Study Suggests Combination of Hypertension, Genetic Risk Factor for Alzheimer Disease May be Associated with Increased Brain Amyloid Deposits in Cognitively Normal Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 18, 2013   JAMA Neurology Study Highlights   A study by Karen M. Rodrigue, Ph.D., of the University of Texas at Dallas, and colleagues suggests that patients with hypertension with at least one genetic risk factor for Alzheimer disease (an apolipoprotein E Ɛ4 allele) showed more β-amyloid…

Study Investigates Prolonged Antibiotic Use in Long-Term Care Facilities

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 18, 2013   JAMA Internal Medicine Study Highlights   An analysis of antibiotic prescribing in long-term care facilities in Canada by Nick Daneman, M.D., M.Sc., of the University of Toronto, Canada, and colleagues suggests that antibiotic treatment courses are often prescribed for long durations and seem to…

Study Examines Outcomes of Screening Mammography for Age, Breast Density, Hormone Therapy

EMBARGOED FOR RELEASE: 3 P.M. (CT) MONDAY, MARCH 18, 2013 Media Advisory: To contact author Karla Kerlikowske, M.D., call Elizabeth Fernandez at 415-514-1592 or email Elizabeth.Fernandez@ucsf.edu. CHICAGO – A study that compared the benefits and harms of the frequency of screening mammography to age, breast density and postmenopausal use of hormone therapy (HT) suggests that…

Study Tracks Variation Between Hospitals in Vena Cava Filter Use

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 18, 2013 Media Advisory: To contact study author Richard H. White, M.D., call Karen Finney at 916-734-9064 or email Karen.Finney@ucdmc.ucdavis.edu. To contact viewpoint author Vinay Prasad, M.D., call the NCI Office of Media Relations at 301-496-6641 or email ncipressofficers@mail.nih.gov. CHICAGO – The frequency of vena cava filter…

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Study Evaluates Clinical Manifestation of Cytomegalovirus Associated Eye Infections in Patients Without HIV

EMBARGOED FOR RELEASE: 3 P.M. (CT), THURSDAY , MARCH 14, 2013   JAMA Ophthalmology Study Highlights   Study Evaluates Clinical Manifestations of Cytomegalovirus Associated Eye Infections in Patients Without HIV   The medical records of 18 patients  (22 affected eyes) were reviewed as part of a case series study in an academic research setting by…

Follow-up of Results, Complications of Combined Rhinoplasty, Genioplasty

EMBARGOED FOR RELEASE: 3 P.M. (CT), THURSDAY, MARCH 14, 2013   JAMA Facial Plastic Surgery Study Highlights   Follow-up of Results, Complications of Combined Rhinoplasty, Genioplasty   Dario Bertossi, M.D., of the University of Verona, Italy, and colleagues examined the long-term results and complications of combined rhinoplasty (nose) and genioplasty (chin). (Online First)   The…

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Study Screened For Post-Partum Depression, Examined Positive Findings

EMBARGOED FOR RELEASE: 3 P.M. (CT), WEDNESDAY, MARCH 13, 2013   JAMA Psychiatry Study Highlights   Study Screened For Post-Partum Depression, Examined Positive Findings   A study by Katherine L. Wisner, M.D., M.S., and colleagues screened postpartum women for depression and examined positive screening findings to determine the timing of the episode’s onset, along with…

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Research Letter Surveys Treatment of Hyperlipidemia in Primary Prevention

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Internal Medicine Study Highlights In a research letter, Michael E. Johansen, M.D., of the University of Michigan, Ann Arbor, and colleagues used an anonymous survey of physicians to examine statin prescribing strategies in relationship to baseline risk of coronary heart disease (CHD). (Online…

Analysis of Complications Following Colonoscopy with Anesthesia Assistance

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Internal Medicine Study Highlights Gregory S. Cooper, M.D., of University Hospitals Case Medical Center, Cleveland, Ohio, and colleagues analyzed the occurrence of hospitalizations for splenic rupture or trauma, colonic perforation and aspiration pneumonia within 30 days of a colonoscopy with or without anesthesia….

Study Suggests Many Colonoscopies for Older Adults May be Inappropriate

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Internal Medicine Study Highlights A study by Kristin M. Sheffield, Ph.D., and colleagues of the University of Texas Medical Branch, Galveston, that analyzed Medicare claims data for Texas and a sample from the United States suggests that many colonoscopies performed in older patients…

Study Investigates Older Adults’ View of Cancer Screening

Editor’s Note: An author video will be available when the embargo lifts. http://bit.ly/KEPNSw   EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013 JAMA Internal Medicine Study Highlights   An interview study by Alexia M. Torke, M.D., M.S., of the Indiana University Center for Aging Research, Indianapolis, and colleagues, sought to examine older adults’…

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Study Examines Cerebrospinal Fluid Markers in Relation to Alzheimer Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Neurology Study Highlights A study by Maureen Handoko, Ph.D., of the University of Minnesota, Minneapolis, and colleagues suggests that in cognitively intact older adults cerebrospinal fluid (CSF) amyloid-β trimers and Αβ*56  were elevated in patients at risk for Alzheimer disease (AD). (Online First)…

Review of Medical Literature Suggests Obesity in Hospitalized Children May Be Associated with Higher Mortality

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Pediatrics Study Highlights A search of available medical literature by Lori J. Bechard, M.Ed., R.D., L.D.N., of Boston Children’s Hospital, and colleagues suggests that childhood obesity may be a risk factor for higher mortality in hospitalized children with critical illness, cancer diagnoses or…

Clinical Trial Examines Advance Care Planning for Teens with Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Pediatrics Study Highlights A randomized controlled clinical trial by Maureen E. Lyon, Ph.D., of the Children’s National Medical Center, Washington, and colleagues examined the efficacy of family-centered advance care planning (ACP) for adolescents with cancer. (Online First)   The clinical trial included 60…

Telemedicine Saves Travel and Time for Patients with Parkinson Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013   JAMA Neurology Study Highlights A randomized clinical trial by E. Ray Dorsey, M.D., M.B.A.., of Johns Hopkins Medicine, Baltimore, and colleagues of 20 patients with Parkinson disease suggests that telemedicine visits could save patients, on average, 100 miles of travel and three hours of…

Study Suggests Possible Marker of Alzheimer Disease Associated With Worse Sleep Quality

Editor’s Note: An author podcast will be available when the embargo lifts at http://bit.ly/MNucEu.   EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, MARCH 11, 2013 JAMA Neurology Study Highlights   Yo-El S. Ju, M.D., and colleagues from the Washington University School of Medicine, St. Louis, suggest in a study that amyloid deposition in the preclinical…