Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.17064?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=060526

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JUNE 5, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16951?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this qualitative study of patient experiences with glucagon-like peptide-1 receptor agonists (GLP-1 RAs), participants described GLP-1 RA therapy functioning as a facilitator rather than a replacement for lifestyle change, emphasizing the need for behavioral interventions alongside pharmacotherapy to sustain treatment benefits. Quality of care was highly variable; thus, standardized guidelines for patient education and clinical support could improve expectation management around likely adverse effects and long-term management.

Corresponding Author: To contact the corresponding author, Isabella de Vere Hunt, MD, email Isabella.deverehunt@phc.ox.ac.uk.

(doi:10.1001/jamanetworkopen.2026.16951)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, JUNE 5, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16773?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Maternal respiratory syncytial virus prefusion F (RSVpreF) vaccination was associated with protection against RSV-associated acute respiratory illness and lower respiratory tract disease hospitalization among infants 90 days or younger. These findings provide early clinical evidence supporting the effectiveness of maternal RSVpreF vaccination in preventing RSV-associated hospitalization in infants.

Corresponding Author: To contact the corresponding author, Anne-Marie Rick, MD, MPH, PhD, email Alejandra Ruiz Leon at ruizleonap@upmc.edu.

(doi:10.1001/jamanetworkopen.2026.16596)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, JUNE 4, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16596?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060426

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: From 2005 to 2025, the proportion of menopause-related searches that were related to commercial products and services increased by 15 to 20 percentage points in the United Kingdom, Australia, and the United States with no difference in the rate of increase by country. Increases appeared earlier in the U.S., with subsequent convergence across countries over time. These results suggest that individuals may be increasingly seeking nonclinical approaches to managing menopause, not only for symptom relief but also for ongoing guidance, tracking, or support outside traditional clinical encounters.

Corresponding Author: To contact the corresponding author, Francesca R. Farina, PhD, email ffarina@uchicago.edu.

(doi:10.1001/jamanetworkopen.2026.16596)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, JUNE 3, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16485?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060326

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this cohort study of U.S. households with children suggest that high out-of-pocket medical costs may make it more difficult for households to afford health-related social needs (i.e., accessing food, paying bills, and living in quality housing), potentially contributing to adverse health outcomes.

Corresponding Author: To contact the corresponding author, Michael Caniglia, PhD, MPA, email Michael.caniglia@nationwidechildrens.org.

(doi:10.1001/jamanetworkopen.2026.16485)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, JUNE 2, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16375?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of patients with early breast cancer, prediagnostic statin use was not associated with higher survival; however, postdiagnostic statin use was associated with lower all-cause and breast cancer–specific mortality among patients with hormone receptor–positive intrinsic subtypes. These findings suggest that statin therapy may improve survival of patients with early hormone receptor–positive subtypes.

Corresponding Author: To contact the corresponding author, Santeri Palmi, MD, email santeri.palmi@tuni.fi.

(doi:10.1001/jamanetworkopen.2026.16375)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, JUNE 2, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16148?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this national cohort study, living in or being wait-listed at transplant centers in high-segregation neighborhoods was associated with lower likelihood of live donor liver transplant (LDLT) access and candidates living in high-segregation neighborhoods with a larger racial and ethnic minority population compared with a larger white population had lower likelihood of LDLT. Investing in high-segregation neighborhoods to address these structural disadvantages may help improve equity in LDLT access.

Corresponding Author: To contact the corresponding author, Alexandra T. Strauss, MD, PhD, MIE, email astraus6@jhmi.edu.

(doi:10.1001/jamanetworkopen.2026.16148)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 12:30 P.M. ET, MONDAY, JUNE 1, 2026

Media advisory: The full study is linked to this news release. This study is being presented at the 2026 American Society of Clinical Oncology Annual Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.15509?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=060126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this randomized clinical trial of patients with advanced cancer, an app-facilitated palliative care intervention helped maintain health-related quality of life and self-efficacy and reduced acute care use compared with usual care.

Corresponding Author: To contact the corresponding author, Wing-Lok Chan, MBBS, email winglok@hku.hk.

(doi:10.1001/jamanetworkopen.2026.15509)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 5:15 P.M. ET, SATURDAY, MAY 30, 2026

Media advisory: The full study is linked to this news release. This study is being presented at the 2026 AcademyHealth Annual Research Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.18999?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=053026

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The numbers of physicians and nurses immigrating from countries with complete immigration bans have significantly increased over the past decade, with these countries contributing nearly 24,000 physicians and 56,000 nurses to the entire U.S. health care workforce in 2023. Communities with physicians and nurses from banned countries were much more likely to experience ongoing health care workforce shortages. The findings of this study suggest that the recent complete immigration ban could reduce the physician and nurse workforce in the U.S. and worsen access to care across already underserved communities.

Corresponding Author: To contact the corresponding author, Hao Yu, PhD, email hao_yu@hphci.harvard.edu.

(doi:10.1001/jamanetworkopen.2026.18999)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 22, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.14115?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This large, multisite cohort study found that antenatal opioid exposure was associated with impaired cerebral cortical folding in newborns. The extent of cerebral cortical impairment differed based on the opioid type and presence of polysubstance exposure. Continued longitudinal neuroimaging and neurodevelopmental assessments are currently underway to examine the trajectory of brain development and clinical significance of these early cortical changes, potentially informing early interventions to support neurodevelopment in this vulnerable population.

Corresponding Author: To contact the corresponding author, Catherine Limperopoulos, PhD, email climpero@childrensnational.org.

(doi:10.1001/jamanetworkopen.2026.14115)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 21, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.13955?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: The findings of this cohort study underscore a gap between evidence and practice. Two-thirds of patients with newly identified heart failure with reduced ejection fraction did not undergo left ventricular ejection fraction reassessment, limiting opportunities to confirm persistence, evaluate reverse remodeling, and identify candidates for treatment. Receipt of guideline-directed medical therapy was modest across groups, even among patients with persistent heart failure with reduced ejection fraction, who derive the greatest benefit.

Corresponding Author: To contact the corresponding author, Brianna M. Goodwin Cartwright, MS, email briannac@truveta.com.

(doi:10.1001/jamanetworkopen.2026.13955)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 20, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.13689?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=052026

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of pediatric emergency department visits, increased pediatric capability was not associated with differences in the patterns of imaging utilization by insurance status or race and ethnicity. Additional efforts are needed to ensure that pediatric capability improves quality and equity of care.

Corresponding Author: To contact the corresponding author, Margaret E. Samuels-Kalow, MD, MPhil, MSHP, email msamuels-kalow@mgb.org.

(doi:10.1001/jamanetworkopen.2026.13689)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 19, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.13399?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051926

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of older adults, participants with less favorable long-term memory trajectories were subsequently less active and more sedentary, suggesting that later-life activity patterns may partly reflect cognitive change.

Corresponding Author: To contact the corresponding author, Mikaela Bloomberg, PhD, email mikaela.bloomberg.19@ucl.ac.uk.

(doi:10.1001/jamanetworkopen.2026.13399)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 18, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11464?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051826

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This post hoc analysis of a randomized clinical trial suggests that high-dose vitamin D3 supplementation in pregnancy is positively associated with visual memory, verbal memory, and flexibility or set shift among offspring measured at age 10 years. These findings strengthen evidence on the association of prenatal vitamin D exposure with childhood cognition.

Corresponding Author: To contact the corresponding author, Bo Chawes, MD, PhD, DMSc, email chawes@copsac.com.

(doi:10.1001/jamanetworkopen.2026.11464)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 15, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.12589?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this randomized clinical trial of major depressive disorder, a single dose of psilocybin was associated with rapid antidepressant effects, observed by day 2 and persisting for more than 3 months on secondary outcomes; psilocybin was generally well tolerated, but some individuals required additional support after dosing due to anxiety. These results suggest that psilocybin may provide a rapid and relatively long-lasting antidepressant effect on major depressive disorder, warranting further investigation into repeated dosing or adjunctive treatment strategies.

Corresponding Author: To contact the corresponding author, Hampus Yngwe, MD, MSc, email hampus.yngwe@ki.se.

(doi:10.1001/jamanetworkopen.2026.12589)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 15, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.13094?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: This study assessed functional outcomes at hospital discharge among children and adolescents who sustained penetrating traumatic brain injury (TBI) during armed conflict in the Gaza Strip and found there was substantial morbidity and mortality. Penetrating TBI, characterized by a breach of the dura mater caused by a projectile or fragment, represents one of the most fatal war-related injuries. Survivors frequently endure neurological impairments alongside long-term psychosocial challenges.

Corresponding Author: To contact the corresponding author, Mohammed Asfa, MD, email asfa1991@gmail.com.

(doi:10.1001/jamanetworkopen.2026.13094)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 15, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.12609?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study, recent COVID-19 vaccination was associated with a reduced risk of SARS-CoV-2 transmission. These findings suggest that COVID-19 vaccination may have an indirect benefit of decreasing transmission and thus reducing overall exposure to SARS-CoV-2.

Corresponding Author: To contact the corresponding author, Sarah E. Smith-Jeffcoat, MPH, email uyi7@cdc.gov.

(doi:10.1001/jamanetworkopen.2026.12609)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 14, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.6783?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051426

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this longitudinal cohort study of mother-child dyads enrolled at the child’s birth, exposure to adverse pregnancy outcomes during gestation, particularly hypertensive disorders of pregnancy, was associated with suboptimal cardiovascular health and arterial injury among offspring in early adulthood. The findings suggest optimizing pregnancy health may support offspring cardiovascular health into early adulthood.

Corresponding Author: To contact the corresponding author, Nilay S. Shah, MD, MPH, email nilay.shah@northwestern.edu.

(doi:10.1001/jamanetworkopen.2026.6783)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 12, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.12191?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this survey study of adult firearm owners who lived in households with children younger than 18 years, more than 1 in 5 reported that at least 1 firearm in their household was both loaded and unlocked, a practice more common when all children in the household were teenagers. More effective approaches to motivating parents to make their firearms inaccessible to both their teenagers and their younger children are needed.

Corresponding Author: To contact the corresponding author, Matthew Miller, MD, MPH, ScD, email ma.miller@northeastern.edu.

(doi:10.1001/jamanetworkopen.2026.12191)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 12, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.12042?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of individuals with stage IV breast cancer, incidence increased significantly overall, across ages, and for both sexes from 2010 through 2021. The percentage of individuals with stage IV vs stages I to III diagnoses also increased. Although overall survival improved, research is warranted to determine factors contributing to increased incidence, including potential changes in natural history of breast cancer, disease screening, and incidence and mortality of other conditions.

Corresponding Author: To contact the corresponding author, Jose P. Leone, MD, email josep_leone@dfci.harvard.edu.

(doi:10.1001/jamanetworkopen.2026.12042)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 12, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16780?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051226

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: Ivermectin-benzimidazole prescribing rose rapidly following celebrity endorsement in January 2025, with disproportionate increases among male patients, white patients, residents of the U.S. South, and individuals with cancer. The elevated prescribing observed among patients with cancer is particularly concerning; individuals facing life-threatening illness may delay or forgo conventional treatments in favor of unproven therapies, potentially allowing their disease to progress.

Corresponding Author: To contact the corresponding author, Michelle S. Rockwell, PhD, email msrock@vt.edu.

(doi:10.1001/jamanetworkopen.2026.16780)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 11, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.12133?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.

About The Study: In this cohort study of patients with breast cancer, findings suggested a potential association between glucagon-like peptide-1 receptor agonist (GLP-1 RA) use and improved outcomes among patients with breast cancer who have obesity and related metabolic conditions. These findings support further evaluation of GLP-1 RA therapy in randomized clinical trials.

Corresponding Author: To contact the corresponding author, Bernard F. Fuemmeler, PhD, MPH, email bernard.fuemmeler@vcuhealth.org.

(doi:10.1001/jamanetworkopen.2026.12133)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, MONDAY, MAY 11, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11835?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=051126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: Nationwide telemedicine adoption was not significantly associated with changes in visits or spending, either overall or when stratified by urbanicity, payer type, or area-level social vulnerability, thus easing concerns about large utilization and spending increases from telemedicine expansion.

Corresponding Author: To contact the corresponding author, John N. Mafi, MD, MPH, email jmafi@mednet.ucla.edu.

(doi:10.1001/jamanetworkopen.2026.11835)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 8, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.6147?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050826

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this repeated cross-sectional study of cross-national mortality, the U.S. had substantially higher death rates than other high-income countries between 1999 and 2022, despite having similar access to advanced medical technology. Many of these excess U.S. deaths could likely be avoided by adopting health and social policies that have benefited other high-income countries. These descriptive findings should be interpreted in light of uncertainty arising from differences in death coding, data completeness, and other aspects of data comparability across countries.

Corresponding Author: To contact the corresponding author, Jacob Bor, PhD, email jbor@bu.edu.

(doi:10.1001/jamanetworkopen.2026.6147)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 10:45 A.M. ET, FRIDAY, MAY 8, 2026

Media advisory: The full study is linked to this news release. This study is being presented at the 2026 Society of General Internal Medicine Annual Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.16556?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050826

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this study, a large language model-based agentic workflow produced hospital course summaries that were frequently used with minimal risk of harm identified. The intervention was associated with a reduction in physician burnout, supporting the viability of AI summarization to mitigate documentation burden.

Corresponding Author: To contact the corresponding author, Francois Grolleau, MD, PhD, email grolleau@stanford.edu.

(doi:10.1001/jamanetworkopen.2026.16556)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 8, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11112?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050826

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this cluster randomized trial of a clinical decision support system for chronic kidney disease in primary care, both the intervention and control groups demonstrated comparable improvements in 6-month outcomes, with no independent effect of the clinical decision support system detected.

Corresponding Authors: To contact the corresponding authors, email Li Yang, PhD, MD (li.yang@bjmu.edu.cn) and Jicheng Lv, MD (chenglv@263.net).

(doi:10.1001/jamanetworkopen.2026.11112)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 8, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11765?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050826

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this nationwide cohort study conducted in Sweden, bidirectional associations were found between premenstrual disorders and psychiatric disorders and conditions, highlighting the need for sex- and menstrual cycle–informed care in psychiatry. Further research is needed to understand the underlying mechanisms shared between premenstrual disorders and psychiatric disorders.

Corresponding Authors: To contact the corresponding authors, email Jing Zhou, MD, MSc (jing.zhou@ki.se) and Donghao Lu, MD, PhD (donghao.lu@ki.se).

(doi:10.1001/jamanetworkopen.2026.11765)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, THURSDAY, MAY 7, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11029?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050726

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this randomized clinical trial, psilocybin appeared to be safe and efficacious for treating cocaine use disorder among individuals from underrepresented and vulnerable populations. Further research is warranted to replicate and expand these findings.

Corresponding Author: To contact the corresponding author, Peter S. Hendricks, PhD, email pshendricks@uabmc.edu.

(doi:10.1001/jamanetworkopen.2026.11029)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 8:45 A.M. ET, THURSDAY, MAY 7, 2026

Media advisory: The full study is linked to this news release. This study is being presented at the 2026 Society of General Internal Medicine Annual Meeting.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.11324?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050726

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this trial-based economic evaluation, Substance Use Treatment and Recovery Team (START; a hospital-based addiction consultation service) was a cost-effective approach for addressing opioid use disorder (OUD) in the inpatient setting by increasing the initiation of medication for OUD and linkage to OUD-focused care after discharge.

Corresponding Author: To contact the corresponding author, Adeyemi Okunogbe, MBChB, PhD, email yemiokunogbe@gmail.com.

(doi:10.1001/jamanetworkopen.2026.11324)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, WEDNESDAY, MAY 6, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.10609?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050626

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this randomized clinical trial, genotype-guided prescribing of selective serotonin reuptake inhibitors (SSRIs) did not improve control of depression symptoms at 3 months compared with usual care but was associated with higher depression remission rates at 6 months. These findings suggest a possible longer-term clinical benefit and indicate that future studies should focus on the durability and long-term impact of genotype-guided prescribing in the management of depressive symptoms.

Corresponding Author: To contact the corresponding author, Josh F. Peterson, MD, MPH, email josh.peterson@vumc.org.

(doi:10.1001/jamanetworkopen.2026.10609)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 5, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.10789?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this cross-sectional survey study of 988 Lifeline leaders, results suggested that most centers struggled to find resources to keep the center fully staffed. If staffing challenges persist, centers could face risks to staff well-being and service quality. Financing and operational strategies that support recruitment and retention will be critical to sustaining the quality and accessibility of 988 Lifeline centers.

Corresponding Author: To contact the corresponding author, Samantha Matthews, MPhil, MPA, email smatthew@rand.org.

(doi:10.1001/jamanetworkopen.2026.10789)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, TUESDAY, MAY 5, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.10810?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050526

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this retrospective comparative effectiveness research study of Medicare beneficiaries, hospital at home was associated with lower in-hospital mortality and emergency department use within 30 days of discharge, but not hospital readmissions within 30 days, compared with traditional inpatient care. These findings support hospital at home as an approach that may maintain similar or better short-term outcomes among appropriately selected patients; future studies should evaluate implementation and equity.

Corresponding Author: To contact the corresponding author, J. Priyanka Vakkalanka, PhD, email priyanka-vakkalanka@uiowa.edu.

(doi:10.1001/jamanetworkopen.2026.10810)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 1, 2026

Media advisory: The full study and commentary are linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.9335?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: In this cohort study of community-living older U.S. persons, poor housing affordability was associated with higher risks of frailty, disability, dementia, and mortality, and poor housing quality was associated with higher risks of frailty, disability, and mortality. These findings highlight housing insecurity as a clinically relevant social determinant of health among older persons.

Corresponding Author: To contact the corresponding author, Robert D. Becher, MD, MS, email robert.becher@yale.edu.

(doi:10.1001/jamanetworkopen.2026.9335)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

JAMA Network Open    

EMBARGOED FOR RELEASE: 11 A.M. ET, FRIDAY, MAY 1, 2026

Media advisory: The full study is linked to this news release.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.10053?guestAccessKey=1b34668e-afe8-4888-aa3d-dd05b3b83eff&utm_source=for_the_media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=050126

About JAMA Network Open: JAMA Network Open is an online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication. 

About The Study: Despite rapid expansion of ultraexpensive drugs in Medicare Part D, this cohort study found that availability in comparable economies remains limited, and internationally unavailable products often have higher per-beneficiary spending, underscoring their fiscal significance.

Corresponding Author: To contact the corresponding author, So-Yeon Kang, PhD, MBA, email soyeon.kang@georgetown.edu.

(doi:10.1001/jamanetworkopen.2026.10053)

Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

#  #  #

For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email media relations.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time http://jamanetwork.com/journals/jamanetworkopen/fullarticle/10.1001/jamanetworkopen.2026.9948?utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_term=043026