Incisional Negative Pressure Wound Therapy for Prevention of Surgical Site Infection

In this systematic review and meta-analysis of 85 RCTs, iNPWT was associated with lower risks of overall, deep, and superficial SSI and several wound complications but potentially higher risks of skin blistering and device-related adverse events. These findings support selective rather than routine use, particularly in patients at elevated risk of incisional wound complications.

Corresponding Author: Shaan Patel, MB BChir, MA, Department of Neurological Surgery, Thomas Jefferson University Hospital, 111 S 11th St, Philadelphia, PA 19107 (shaan.patel@jefferson.edu).

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