Mapping 2-Year Psychiatric and Neurologic Risks After Infections Across Body Systems and Age Groups

Do risks of psychiatric and neurologic disorders increase in the 2 years after infections, and how do they vary by body system affected and age?In this multicohort study of more than 1 million infections during which patients were hospitalized, infections were associated with significantly higher risk for most outcomes across age groups, though less so in children. Infectious encephalitides were a leading infectious risk factor for most disorders, whereas other infections were more disorder specific.These findings suggest that infections are important risk factors for psychiatric and neurologic disorders, can guide research into underlying mechanisms, and may help improve future pandemic preparedness.

Corresponding Author: Maxime Taquet, BM, BCh, PhD, Department of Psychiatry, University of Oxford, Warneford Ln, Oxford OX3 7JX, United Kingdom (maxime.taquet@psych.ox.ac.uk).

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