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Young Male With Multifocal Oral UlcersYoung Male With Multifocal Oral Ulcers—CaseYoung Male With Multifocal Oral Ulcers—Diagnosis

JAMA Otolaryngology–Head & Neck Surgery 10.1001/jamaoto.2026.1251

June 04, 2026 at 11:00 AM EDT

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A 20-year-old male presented with a 5-month history of large, painful, multifocal oral ulcers involving the vermillion of the right upper lip and the upper-right labial vestibule. What is your diagnosis?

Corresponding Author: Tyler R. Selkin, BS, Department of Pathology, University of Texas Southwestern Medical Center, 6201 Harry Hines Blvd, Dallas, TX 75390 (tylerselkin@outlook.com).

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