Research Letter

Reported Metformin Use and Age-Related Macular Degeneration in Patients With Diabetes

JAMA Ophthalmology 10.1001/jamaophthalmol.2026.1799

June 04, 2026 at 11:00 AM EDT

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This cohort study compared the incidence of age-related macular degeneration in users and nonusers of metformin among multiethnic Asian patients with diabetes.

Corresponding Author: Ching-Yu Cheng, MD, PhD, Centre for Innovation and Precision Eye Health, Yong Loo Lin School of Medicine, National University of Singapore, 21 Lower Kent Ridge Rd, Singapore 119077 (chingyu.cheng@nus.edu.sg).

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