Diagnostic Accuracy of a Retinal Birefringence Scanning Device Compared With a Traditional Autorefraction Device

How does a retinal birefringence scanning device compare with a traditional autorefraction device to detect amblyopia, strabismus, or visually significant refractive error?This diagnostic accuracy study of 195 children referred for failed vision screening or strabismus found that the traditional autorefraction device outperformed the retinal birefringence device with higher sensitivity for detecting amblyopia or refractive error, with no differences in specificity identified.Study findings show that this direct comparison of a traditional vs newer screening mechanism did not demonstrate any improvement in diagnostic accuracy to detect amblyopia, strabismus, or visually significant refractive error in children.

Corresponding Author: Julius T. Oatts, MD, MHS, Division of Pediatric Ophthalmology, Children’s Hospital of Philadelphia, 3500 Civic Center Blvd, Philadelphia, PA 19104 (oattsj2@chop.edu).

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