Original Investigation

Racial and Ethnic Disparities in US Colorectal Cancer Mortality by County, Sex, and Age

JAMA Oncology 10.1001/jamaoncol.2026.3194

August 20, 2026 at 11:00 AM EDT

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This cross-sectional study found significant improvements in CRC mortality in adults aged 45 years or older at the national level and across all racial and ethnic populations between 2000 and 2019. However, CRC mortality rates remain extremely high in some counties and populations. These findings can help inform targeted intervention strategies for communities at highest risk.

Corresponding Author: Paula D. Strassle, PhD, MSPH, University of Maryland, 8314 Paint Branch Dr, Biomolecular Sciences Building, Room 3114F, College Park, MD, 20740 (pdstrass@umd.edu).

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