Original Investigation

Research Study Attrition and Participant-Informed Retention Strategies Among Cancer Survivors

JAMA Network Open 10.1001/jamanetworkopen.2026.33498

September 14, 2026 at 11:00 AM EDT

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In this mixed methods cohort study of survivors enrolled in a large longitudinal breast cancer cohort, nonresponsiveness increased over time and was socially, clinically, and organizationally patterned. Survey and qualitative findings suggested that participant-centered retention strategies should combine procedural flexibility, remote follow-up, navigation support, targeted communication, and regular feedback and informed the design of a digitally enabled, multimodal retention intervention.

Corresponding Author: Antonio Di Meglio, PhD, Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines, Gustave Roussy, Inserm, Centre de recherche en Epidémiologie et Santé des Populations, 114 Rue Edouard Vaillant, 94800, Villejuif, France (antonio.di-meglio@gustaveroussy.fr).

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