Heterogeneity of Critical Organ Dysfunction During Late-Onset Bacteremia in Preterm Infants

In this cohort study of late-onset single-pathogen bacteremia in infants at 33 weeks’ gestation or less, late-onset bacteremia in preterm infants was associated with substantial heterogeneity in the severity and temporal course of critical organ dysfunction. Characterization of organ dysfunction dynamics may provide a more informative framework for studying neonatal sepsis than binary microbiologic classifications alone.

Corresponding Author: James L. Wynn, MD, Department of Pediatrics, University of Florida, 1600 SW Archer Rd, PO Box 100296, Gainesville, FL 32610-0296 (james.wynn@peds.ufl.edu).

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