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Neonatal Unit Colonization Pressure and Acquisition of Extended-Spectrum β-Lactamase Gut Colonization

JAMA Network Open 10.1001/jamanetworkopen.2026.32644

September 15, 2026 at 11:00 AM EDT

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In this cross-sectional study, ESBL colonization pressure was associated with individual risk of acquiring ESBL on the neonatal unit. Unit-level interventions targeting colonization rather than infection may have important direct and indirect benefits in units with high colonization pressure.

Corresponding Author: Aislinn Cook, MSc, School of Health and Medical Sciences, City St George’s University of London, Cranmer Terrace, SW17 0RE, London, United Kingdom (aicook@citystgeorges.ac.uk).

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