Editor's Pick Original Investigation

Mental Health Symptom Changes by Sex or Gender Before and During the COVID-19 Pandemic

JAMA Network Open 10.1001/jamanetworkopen.2026.27595

August 06, 2026 at 11:00 AM EDT

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This systematic review and meta-analysis assesses changes in mental health symptoms from before to during the COVID-19 pandemic by sex and gender.

Visit JAMA+ Women's Health to explore Women's Health research from across JAMA Network curated by Linda Brubaker, MD.

Corresponding Author: Brett D. Thombs, PhD, Lady Davis Institute for Medical Research, Jewish General Hospital, 3755 Cote Ste-Catherine, Pavilion H4.83, Montreal, QC H3T 1E2, Canada (brett.thombs@mcgill.ca).

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