Cognitive Rehabilitation and Functional Outcomes in Long COVID–Related Cognitive Impairment
JAMA Network Open 10.1001/jamanetworkopen.2026.20687July 01, 2026 at 11:00 AM EDT
Does cognitive rehabilitation (CR) improve goal attainment, cognitive, and clinical outcomes in people with cognitive impairment as a part of long COVID?In this randomized clinical trial of 78 adults with prior COVID-19 infection and objective cognitive impairment, CR resulted in significantly greater functional goal attainment scores compared with treatment as usual at 3 months after randomization, and this significant difference remained at 6 months.These findings suggest that CR can effectively treat cognitive impairment in long COVID.
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