Original Investigation

Long-Term Resistance Training and Risk of Type 2 Diabetes

JAMA Network Open 10.1001/jamanetworkopen.2026.19420

June 22, 2026 at 11:00 AM EDT

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Is long-term resistance training, including volume and consistency, associated with reduced type 2 diabetes (T2D) risk, and how are combinations with aerobic activity and sedentary behavior additionally associated with T2D risk?In this cohort study of 143 715 adults followed up for 19.2 years, consistently high levels of resistance training were associated with the greatest reduction in T2D risk. In analyses of lifestyle combinations, meeting both aerobic and resistance training recommendations and limiting television viewing was associated with the lowest risk.These findings suggest that consistent resistance training, particularly when combined with adequate aerobic activity and limited sedentary behavior, may be an important component of recommendations for T2D prevention.

Corresponding Authors: Chao Zheng, MD, Zhejiang University School of Medicine, The Second Affiliated Hospital, Shangcheng District, Hangzhou 310000, China (chao_zheng@zju.edu.cn); Edward Giovannucci, MD, ScD, Department of Nutrition, Harvard T. H. Chan School of Public Health, 677 Huntington Ave, Boston, MA 02115 (egiovann@hsph.harvard.edu).

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