Inpatient Characteristics and Outcomes of Venous Thromboembolism Among Children and Adolescents

To what extent are venous thromboembolism (VTE) and pulmonary embolism in hospitalized pediatric patients associated with specific risks, treatments, and outcomes?This nationwide inpatient cohort study found 14 108 cases of VTE among children and adolescents, for a hospital-based incidence of VTE of 15.3 per 10 000 pediatric cases per year. A total of 23.5% of VTE cases occurred in infants younger than 1 year; these were associated with the highest health economic burden and were independently associated with increased in-hospital mortality.This study suggests that the hospital-based incidence of VTE among pediatric patients is 30- to 100-fold increased compared with reported population-based incidence rates, and very young children are at particular risk of fatal outcomes.

Corresponding Author: Eva Freisinger, MD, PhD, Department of Angiology, University Hospital Leipzig, Liebigstrasse 20, 04103 Leipzig, Germany (eva.freisinger@medizin.uni-leipzig.de)

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.