Public Acceptance of Emergency Research Without Prior Consent in Stroke

Is emergency research without prospective consent (ERWPC) for hyperacute stroke acceptable to the public in Japan, where no established pathway exists?In this survey study involving 1000 adults in Japan, 60.5% accepted ERWPC in at least 1 hypothetical stroke trial scenario, whereas 33.4% were willing to join a standard trial that required prospective informed consent. ERWPC acceptance was associated with benefit-risk considerations, research familiarity, and consent modality preferences.These findings suggest that responses to emergency research may differ from general attitudes toward trial participation.

Corresponding Author: Masaru Suzuki, MD, PhD, Department of General Internal Medicine, International University of Health and Welfare Ichikawa General Hospital, 5-11-13 Sugano, Ichikawa, Chiba, 2728513, Japan (masuzume@outlook.com).

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