Research Letter

Aspirin Use for Secondary Prevention Amid Negative Messaging in Patients With Cardiovascular Disease

JAMA Network Open 10.1001/jamanetworkopen.2026.16605

June 04, 2026 at 11:00 AM EDT

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This cross-sectional study assesses whether aspirin use for secondary prevention changed from 2015 to 2020 and investigates the factors associated with stopping therapy among adults with atherosclerotic cardiovascular disease.

Corresponding Author: Jeremy R. Van’t Hof, MD, MS, Cardiovascular Division and Lillehei Heart Institute, University of Minnesota Medical School, 420 Delaware St SE, MMC 508, Minneapolis, MN 55455 (vanth008@umn.edu).

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