Original Investigation

Homelessness and HIV Treatment Among Men Who Have Sex With Men Across US Funding Contexts

JAMA Network Open 10.1001/jamanetworkopen.2026.13609

May 19, 2026 at 11:00 AM EDT

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Is homelessness associated with lower current antiretroviral therapy (ART) use among gay, bisexual, and other men who have sex with men (GBMSM) living with HIV in the US, and is this association moderated by Housing Opportunities for Persons With HIV/AIDS (HOPWA), a federal housing program for people living with HIV?In this cross-sectional analysis of 2017 to 2023 AMIS data including 4911 GBMSM living with HIV, homelessness was associated with lower current ART use. This association was greater in states with at- or below-median HOPWA funding and appeared to be attenuated in states with above-median funding.These findings suggest that higher per-person HOPWA funding may mitigate homelessness-related barriers to ART use among GBMSM living with HIV.

Corresponding Author: Yuanqi Mi, ScM, Department of Epidemiology, Johns Hopkins University, 615 N Wolfe St, Baltimore, MD 21205 (ymi3@jhu.edu).

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