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Autonomous Oxygen Titration for Maintaining Normoxemia in Acutely Ill Adults

JAMA Internal Medicine 10.1001/jamainternmed.2026.4023

August 03, 2026 at 1:00 PM EDT

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In this randomized clinical trial among adults hospitalized with an acute illness or injury and receiving supplemental oxygen, autonomous oxygen titration substantially increased the proportion of time spent in normoxemia and decreased time spent in hypoxemia compared with usual care.

Meeting Information:

This paper will be presented at Military Health System Research Symposium.

Corresponding Authors: David J. Douin, MD, MSc, Department of Anesthesiology, University of Colorado Anschutz School of Medicine (david.douin@cuanschutz.edu), and Adit A. Ginde, MD, MPH, Department of Emergency Medicine, University of Colorado Anschutz School of Medicine, 12401 E 17th Ave, MS B-215, Aurora, CO 80045 (adit.ginde@cuanschutz.edu).

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