Viewpoint

Are Large Language Models Good or Bad for Brain Health?

JAMA Internal Medicine 10.1001/jamainternmed.2026.2212

June 15, 2026 at 11:00 AM EDT

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This Viewpoint discusses potential consequences of large language model use for long-term cognitive health and risk of dementia and suggests strategies for gathering evidence to study this topic.

Corresponding Author: Alexander Chaitoff, MD, MPH, Center for Clinical Management Research, VA Ann Arbor Healthcare System, 2800 Plymouth Rd, Bldg 16, Room 332W, Ann Arbor, MI 48109 (amchait@med.umich.edu).

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