Original Investigation

Real-Time Prescription Benefit Tool Availability and Prescription Medication Fill Rates

JAMA Health Forum 10.1001/jamahealthforum.2026.2739

August 14, 2026 at 11:00 AM EDT

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In this post hoc analysis of a cluster randomized clinical trial, there was no change in overall prescription fill rates, but among high-cost drugs, the RTPB tool increased fill rates, particularly among patients from low-income communities. However, RTPB recommendations were made for a small proportion of orders, limiting the applicability of the findings to a narrow segment of the randomized population.

Corresponding Author: Sunita M. Desai, PhD, Department of Population Health, NYU Grossman School of Medicine, 227 E 30th St, New York, NY 10016 (sunita.desai@nyu.edu).

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