Original Investigation

Long-Term Effectiveness, Safety, and Survival of Dupilumab in Pediatric Atopic Dermatitis

JAMA Dermatology 10.1001/jamadermatol.2026.3548

September 16, 2026 at 11:00 AM EDT

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The results of this cohort study suggest that dupilumab demonstrates long-term effectiveness and safety in pediatric AD in a clinical setting. Younger children show higher NRS scores for pruritus and greater QoL impairment and discontinue treatment more often due to administration problems, highlighting age-specific challenges.

Corresponding Author: Marlies de Graaf, MD, PhD, Heidelberglaan 100, PO box 85500, 3584 CX Utrecht, The Netherlands (m.degraaf-10@umcutrecht.nl).

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