Brief Report

Vutrisiran Treatment and Changes in Cardiac Parameters and Amyloid Burden Assessed by Cardiovascular MRI

JAMA Cardiology 10.1001/jamacardio.2026.2812

August 12, 2026 at 11:00 AM EDT

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Results of this selected ATTR-CM cohort study show that treatment with vutrisiran was associated with favorable changes in parameters relating to cardiac structure, function, and amyloid burden.

Corresponding Author: Marianna Fontana, MD, PhD, National Amyloidosis Centre, University College London, Division of Medicine, Royal Free Hospital Campus, Rowland Hill Street, London NW3 2PF, United Kingdom (marianna.fontana@nhs.net).

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