Digitally Enabled Quality Improvement Intervention and LDL-C Control in Atherosclerotic Cardiovascular Disease

Does a digitally enabled, multifaceted, quality improvement intervention improve low-density lipoprotein cholesterol (LDL-C) control among patients with established atherosclerotic cardiovascular disease? In this cluster randomized clinical trial including 1465 patients across 28 outpatient clinics, the intervention resulted in a statistically significant reduction in mean LDL-C concentration at 6 months and higher rates of LDL-C target attainment and intensive combination lipid-lowering therapy compared with usual care. Results of this study show that digitally enabled, multifaceted, quality improvement strategies can improve lipid management and reduce evidence-practice gaps in secondary cardiovascular prevention in real-world settings.

Corresponding Author: M. Julia Machline-Carrion, MD, PhD, epHealth, 4150 José Carlos Daux Rd, Room 12, Saco Grande, Florianópolis, SC, 88032-005, Brazil (mjuliacarrion@gmail.com).

Link to the article in your story

We encourage you to link out to this article in your story using the link below. It includes an access token that will give free access to the article for your readers up to one year after publication. (The link will be live after the article publishes and embargo is lifted.)

Please see the article for additional information, including full author list, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

Need more information? Contact us.