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Original Investigation

Anticoagulation Monotherapy vs Antiplatelet Monotherapy After Transcatheter Aortic Valve Implant

JAMA 10.1001/jama.2026.17036

August 30, 2026 at 5:45 AM EDT

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A strategy of NOAC monotherapy after TAVI reduced the incidence of HALT and was noninferior for bleeding, thromboembolic events, or death compared with acetylsalicylic acid monotherapy. These findings suggest that anticoagulation therapy can be beneficial after TAVI in selected patients.

Meeting Information: ESC 2026

This paper will be presented during European Society of Cardiology Congress in Munich, Germany.

Local Embargo Time: 11:45 A.M. CEST.

ESC Presentation: Oyvind H Lie will simultaneously present the findings during the Hot Line 7 session in the Main Auditorium.

Corresponding Author: Øyvind H. Lie, MD, PhD, MSc, Department of Cardiology, Oslo University Hospital, Rikshospitalet, PO Box 4950 Nydalen, 0424 Oslo, Norway (oyvlie@gmail.com).

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