Review

Idiopathic Normal Pressure Hydrocephalus

JAMA 10.1001/jama.2026.15519

September 14, 2026 at 11:00 AM EDT

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iNPH affects approximately 1% to 4% of adults 65 years and older and is associated with gait impairment, cognitive decline, and urinary dysfunction. Symptoms improve in approximately 70% to 90% of patients with iNPH who undergo shunt surgery.

Corresponding Author: Mark G. Luciano, MD, PhD, Department of Neurosurgery, Johns Hopkins University, 600 N Wolfe St, Baltimore, MD 21287 (markluciano@jhu.edu).

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