Research Letter

Characteristics of Patients Choosing Intravenous Moderate Sedation for IUD Placement

JAMA 10.1001/jama.2026.15294

September 17, 2026 at 11:00 AM EDT

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This study examined the prevalence of intravenous moderate sedation (IVS) for intrauterine device (IUD) placement when universally offered, as well as the demographic, reproductive, and social factors associated with its use.

In this study of 1,324 patients undergoing IUD placement at a multisite Massachusetts clinic, 20% received intravenous moderate sedation when it was universally offered. In multivariable analyses, sedation use was associated with nulliparity, gender identity, depression or anxiety diagnosis, and pelvic pain-related diagnoses.

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Corresponding Author: Armide Storey, MD, Department of Obstetrics and Gynecology, Complex Family Planning Division, Brigham and Women’s Hospital, 75 Francis St, Boston, MA 02115 (astorey@mgb.org).

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