Original Investigation

Gastric Residual Volume Assessment in Critically Ill Children

JAMA 10.1001/jama.2026.10639

June 12, 2026 at 6:00 AM EDT

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Is not routinely assessing gastric residual volume noninferior to regular assessment to guide enteral feeding in children with critical illness?In this randomized trial of 4700 children receiving invasive ventilation, not assessing gastric residual volume regularly was noninferior to usual care in terms of a composite of length of ventilation and mortality, but significantly increased the proportion of children reaching nutritional targets at 72 hours.In children receiving invasive ventilation, the routine assessment of gastric residual volume did not alter clinical outcomes and impaired enteral feeding.

Corresponding Author: Lyvonne N. Tume, PhD, Edge Hill University Faculty of Health Social Care and Medicine, St Helens Road, Ormskirk L39 4QP, United Kingdom (Lyvonne.tume@edgehill.ac.uk; l.n.tume@ljmu.ac.uk).

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