Hair Practices May Be Barrier to Physical Activity for Some African-American Women

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012 Media Advisory: To contact Amy J. McMichael, M.D., call Bonnie Davis at 336-716-4977 or email bdavis@wakehealth.edu. CHICAGO – A study that surveyed 103 African-American women suggests that nearly 40 percent of the women reported avoiding exercise at times because of their hair, according to a…

Study Examines Risk Reduction and Screening for Ovarian Cancer Among Women Following BRCA Testing

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012 Media Advisory: To contact Gabriel N. Mannis, M.D., call Elizabeth Fernandez at 415-514-1592 or email Elizabeth.Fernandez@UCSF.edu. To contact commentary corresponding author Victor Grann, M.D., M.P.H., call the Columbia University Medical Center Office of Communications at 212-305-3900 or email cumcnews@columbia.edu. CHICAGO – Following BRCA testing, many…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012   Archives of Dermatology Study Highlights A study that surveyed 103 African-American women suggests that nearly 40 percent of the women reported avoiding exercise at times because of their hair (Online First; see news release below). The vasodilator nifedipine, a calcium channel blocker, may be…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012   Archives of Internal Medicine Study Highlights Following BRCA testing, many women who are non-BRCA carriers undergo risk-reducing procedures and additional ovarian cancer screenings, despite limited data to determine the effectiveness of these interventions among the general population (Online First; see news release below). A…

Inpatient Bariatric Procedures for Adolescents Appear to Have Plateaued Since 2003

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012 Media Advisory: To contact corresponding author Randall S. Burd, M.D., Ph.D., call Jennifer L. Stinebiser or Emily Hartman at 202-476-4500 or email JStinebi@childrensnational.org or EHartman@cnmc.org. CHICAGO – Inpatient bariatric procedures among adolescents appear to have plateaued since 2003 to about 1,000 procedures annually, and the…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 17, 2012   Archives of Pediatrics & Adolescent Medicine Study Highlights Inpatient bariatric procedures among adolescents appear to have plateaued since 2003 to about 1,000 procedures annually, and the preferred type of operation has changed to minimally invasive laparoscopic procedures from open procedures (Online First, see news…

Cautionary Findings in Study of Web-Based Tool for Children with Flu-Like Illness

FOR RELEASE: 10 A.M. (CT), WEDNESDAY, DECEMBER 12, 2012 Media Advisory: To contact corresponding author Arthur L. Kellermann, M.D., M.P.H., call Warren Robak at 310-451-6913 or email robak@rand.org. CHICAGO – While parents and caregivers reported that a web-based triage tool for children with influenza-like illness was easy to understand and use, the tool’s underlying mathematical…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012   Archives of General Psychiatry Study Highlights Parents of children who committed suicide appear to be at increased risk for adverse mental health outcomes (including depression, anxiety, alcohol use or dependence, drug abuse or dependence, suicide attempts and dementia), and social outcomes (low or loss…

Study Suggests Vision Insurance Associated with Eye-Care Visits, Better Reported Vision

EMBARGOED FOR RELEASE: 10 A.M. (CT), MONDAY, DECEMBER 10, 2012 Media Advisory: To contact Sudha Xirasagar, M.B.B.S., Ph.D., call Karen Petit at 803-477-1971 or email kpetit@mailbox.sc.edu. CHICAGO – Vision insurance for working-age adults appears to be associated with having eye care visits and reporting better vision, compared with individuals without insurance, according to a report…

Archives of Ophthalmology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012   Archives of Ophthalmology Study Highlights The odds of individuals with open-angle glaucoma undergoing visual field testing decreased for all racial/ethnic groups from 2001 through 2009, but the odds decreased the most for Hispanic men and women in a study of enrollees in a large…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012   Archives of Internal Medicine Study Highlights Use of a personal digital assistant (PDA) and telephone coaching appears to enhance short-term weight loss when used in conjunction with an existing physician-directed weight loss treatment program (Online First; see news release below). Two adapted diabetes lifestyle…

Study Suggests Odds of Visual Field Testing for Glaucoma Decreased Most for Hispanics in Past Decade

EMBARGOED FOR RELEASE: 10 A.M. (CT), MONDAY, DECEMBER 10, 2012 Media Advisory: To contact Joshua D. Stein, M.D., M.S., call Betsy Nisbet at 734-647-5586 or email bsnisbet@umich.edu. To contact editorial author Eve J. Higginbotham, S.M., M.D., call Lesley Ward at 202-828-0655 or email lward@aamc.org. CHICAGO – The odds of individuals with open-angle glaucoma undergoing visual…

Diabetes Prevention Program Interventions Lead To Reduced BMI over Usual Care

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012 Media Advisory: To contact author Jun Ma, M.D., Ph.D., call Cynthia Greaves at 650-934-8616 or 650-444-3019 or email greavec@pamf.org. CHICAGO – Two adapted diabetes lifestyle interventions resulted in weight loss, as well as improvements in waist circumference and fasting plasma glucose level, for overweight or…

Binge Eating, Overeating May Be Associated with Initiating Use of Marijuana, Other Drugs

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012 Media Advisory: To contact Kendrin Sonneville, Sc.D., R.D., call Erin Tornatore at 617-919-3110 or email erin.tornatore@childrens.harvard.edu. CHICAGO – Overeating and binge eating may be associated with initiating use of marijuana and other drugs in a study of adolescents and young adults, according to a study…

Addition of Technology to Standard Weight Loss Plan Appears Beneficial for Greater Weight Loss

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 10, 2012 Media Advisory: To contact Bonnie Spring, Ph.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. To contact commentary corresponding author Goutham Rao, M.D., call Andy Buchanan at 847-570-5732 or email abuchanan@northshore.org. CHICAGO – Use of a personal digital assistant (PDA) and telephone coaching appears to…

Also Appearing in This Issue of JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Study Finds Association Between Weight of Pancreas and Potential Diabetes Biomarker Autopsy and imaging studies suggest that among adults with type 1 diabetes (T1D), their pancreas is smaller and weighs less than the pancreas of adults without the disease. However, it is unknown when pancreatic…

Prevalence of Visual Impairment in U.S. Increases

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author David S. Friedman, M.D., M.P.H., Ph.D., call John Lazarou at 410-502-8902 or email jlazaro1@jhmi.edu. To contact editorial co-author David C. Musch, Ph.D., M.P.H., call Betsy Nisbet at 734-647-5586 or email bsnisbet@umich.edu. CHICAGO – The prevalence of nonrefractive visual impairment…

Combination Therapy May Help Decrease Sleep Apnea Symptoms at Higher Altitudes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 11, 2012 Media Advisory: To contact corresponding author Konrad E. Bloch, M.D., email konrad.bloch@usz.ch. CHICAGO – For individuals with obstructive sleep apnea traveling to higher altitudes (which may exacerbate symptoms), use of a combination therapy resulted in improvement in symptoms including  reduced insomnia and better control of…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 3, 2012 Archives of General Psychiatry Study Highlights A population-based study in rural Thailand suggests that parents with all their children migrated out of the rural area at baseline had a lower odds of depression at one-year follow-up compared with parents with no or only some children…

Study Examines Psychotropic Medication Use Among U.S. Adolescents with Mental Disorders

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 3, 2012 Media Advisory: To contact Kathleen Merikangas, Ph.D., call Colleen Labbe or Jim McElroy at 301-443-4536 or email NIMHpress@mail.nih.gov. To contact editorial author David Rubin, M.D., M.S.C.E., call Dana Mortensen at 267-426-6092 or email mortensen@email.chop.edu. CHICAGO – A survey finds that 14.2 percent of adolescents ages…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 3, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A survey finds that 14.2 percent of adolescents ages 13 to 18 years with any mental disorder reported being treated with a psychotropic medication in the last 12 months, which researchers suggest challenges concerns about widespread overmedication…

Longer Treatment for Male Urinary Tract Infection Not Associated with Reduced Early or Late Recurrence Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 3, 2012 Media Advisory: To contact study and research letter author Dimitri M. Drekonja, M.D., M.S., call Ralph Heussner at 612-467-3012 or email ralph.heussner@va.gov. To contact invited commentary author Barbara W. Trautner, M.D., Ph.D., call Dipali Pathak at 713-798-6826 or email pathak@bcm.edu. CHICAGO – A study of…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, DECEMBER 3, 2012 Archives of Internal Medicine Study Highlights A study of more than 33,000 outpatient male veterans with urinary tract infection (UTI) suggests that compared to patients who received a shorter duration of antimicrobial therapy (for seven days or less), patients who received a longer duration of…

Viewpoints in This Week’s JAMA

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Overcoming the Obstacles to Research During Residency – What Does It Take? Michael B. Rothberg, M.D., M.P.H., of the Cleveland Clinic, writes that “although most physicians work as clinicians and never perform research, the Accreditation Council for Graduate Medical Education requires that residents ‘participate in…

Study Examines Attitudes of Medical Students’ Toward Industry Following COI Disclosures by Preclinical Lecturers

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Deborah Korenstein, M.D., call Kevin Orozovich at 212-241-9200 or email newsmedia@mssm.edu. Azalea Kim, M.P.A., of the Mount Sinai School of Medicine, New York, and colleagues studied the association between routine conflicts of interest (COI) disclosure with preclinical medical students…

Bias May Exist in Rating of Medical Trainees

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Peter Yeates, M.B.B.S., M.Clin.Ed., email peter.yeates@manchester.ac.uk. Peter Yeates, M.B.B.S., M.Clin.Ed., of the University of Manchester, United Kingdom, and colleagues conducted a study to examine whether observations of the performance of postgraduate year 1 physicians influence raters’ scores of subsequent performances. “The…

Research Evaluates Possible Benefit of Multiple Mini-Interviews as Part of Medical School Admission Process

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Kevin W. Eva, Ph.D., call Brian Kladko at 604-827-3301 or email brian.kladko@ubc.ca. Kevin W. Eva, Ph.D., of the University of British Columbia, Vancouver, and colleagues conducted a study to determine whether students deemed acceptable through a revised admissions protocol using a…

Clinically Integrated E-Learning of Evidence-Based Medicine Improves Knowledge, Skills in Resource-Limited Countries

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact corresponding author Khalid S. Khan, M.B.B.S., M.Sc., email k.s.khan@qmul.ac.uk. Regina Kulier, M.D., of the World Health Organization, Geneva, Switzerland, and colleagues conducted a study to evaluate the effects of a clinically integrated e-learning evidence-based medicine (EBM) course on knowledge, skills, and…

Program of Protected Time For Sleep Improves Morning Alertness For Medical Interns

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Kevin G. Volpp, M.D., Ph.D., call Jessica Mikulski at 215-349-8369 or email jessica.mikulski@uphs.upenn.edu Kevin G. Volpp, M.D., Ph.D., of the Philadelphia Veterans Affairs Medical Center and University of Pennsylvania, Philadelphia, and colleagues conducted a study to determine whether a protected sleep…

Shorter Rotation for Attending Physicians Does Not Appear to Have Adverse Effects on Patients; May Decrease Physician Burnout

Embargoed for Release: 3 p.m. CT Tuesday, December 4, 2012 Media Advisory: To contact Brian P. Lucas, M.D., M.S., call Nancy Di Fiore at 312-942-5159 or email Nancy_DiFiore@rush.edu. Brian P. Lucas, M.D., M.S., of the Cook County Health and Hospitals System and Rush Medical College, Chicago, and colleagues conducted a study to compare the effects…

Low Percentage of Medical Residents Plan to Practice General Internal Medicine

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, DECEMBER 4, 2012 Media Advisory: To contact Colin P. West, M.D., Ph.D., call Alyson Fleming at 507-284-5005 or email newsbureau@mayo.edu. Colin P. West, M.D., Ph.D., and Denise M. Dupras, M.D., Ph.D., of Mayo Clinic, Rochester, Minn., conducted a study to evaluate career plans of internal medicine residents. “General…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Earnings of U.S. Physicians Grow Less Than Other Health Professionals   “Understanding trends in physician earnings is important given health care cost growth and proposed Medicare physician fee reductions,” writes Seth A. Seabury, Ph.D., of the RAND Corporation, Santa Monica, Calif., and colleagues. National surveys…

Study Suggests Eliminating Medicare Consultation Payments was Associated with a Net Increase in Spending

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Media Advisory: To contact Zirui Song, Ph.D., call David Cameron at 617-432-0441 or email david_cameron@hms.harvard.edu. To contact editorial author Patrick G. O’Malley, M.D., M.P.H., call Sharon Willis at 301-295-3578 or email sharon.willis@usuhs.edu. CHICAGO – A study of Medicare claims data suggests that eliminating payments for…

Exposure to Traffic Pollution in Pregnancy, 1st Year of Life Appears Associated with Autism

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Media Advisory: To contact Heather E. Volk, Ph.D., M.P.H., call Leslie Ridgeway at 323-442-2823 or email lridgewa@usc.edu. To contact editorial author Geraldine Dawson, Ph.D., call Thania Benios at 919-962-8596 or email thania_benios@unc.edu. CHICAGO – Exposure to traffic-related air pollution, particulate matter and nitrogen dioxide during…

Anticoagulation Treatment For Longer Than Three Months After Aortic Valve Replacement Associated With Decreased Risk of Cardiovascular Death

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Charlotte Merie, M.D., email c.merie@mail.dk. To contact editorial co-author Shamir R. Mehta, M.D., M.Sc., call Veronica McGuire at 905-525-9140, ext. 22169, or email vmcguir@mcmaster.ca. CHICAGO – Although current guidelines recommend 3 months of anticoagulation treatment after bioprosthetic aortic valve replacement surgery,…

Risk of Pertussis Increases as Time Since Last Dose of DTaP Vaccine Lengthens

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Lara K. Misegades, Ph.D., M.S., call Alison Patti at 404-639-3286 or email APatti@cdc.gov. To contact editorial co-author Eugene D. Shapiro, M.D., call Karen Peart at 203-432-1326 or email karen.peart@yale.edu. CHICAGO – In an examination of cases of childhood pertussis in California,…

Studies Examine Whether Therapies for Heart Failure Are Associated With Improved Survival

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 27, 2012 Media Advisory: To contact Adrian F. Hernandez, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact Lars H. Lund, M.D., Ph.D., email lars.lund@alumni.duke.edu. To contact editorial author James C. Fang, M.D., call Mike Ferrari at 216-844-7239 or email Mike.Ferrari@uhhospitals.org. CHICAGO – An…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Archives of General Psychiatry Study Highlights Exposure to traffic-related air pollution, particulate matter and nitrogen dioxide during pregnancy and during the first year of a child’s life appears to be associated with an increased risk of autism (Online First, see news release below). A multicenter…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Archives of Internal Medicine Study Highlights A study of Medicare claims data suggests that eliminating payments for consultations commonly billed by specialists was associated with a net increase in spending on visits to both primary care physicians and specialists (Online First, see news release below)….

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Archives of Neurology Study Highlights A study of 66 veterans who met the definition of Gulf War illness syndromes [impaired cognition, confusion-ataxia (lack of coordination) or central neuropathic (nerve) pain] and 31 veterans in a control group suggests that a well-validated research case definition of…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights Total average sleep was estimated at more than 13 hours a day for infants and decreased steadily throughout childhood and early adolescence until it reached about nine hours a day for adolescents 14 to 18 years old,…

Archives of Facial Plastic Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 26, 2012 Archives of Facial Plastic Surgery Study Highlights A review article examining injectable facial fillers suggests that the safety and efficacy of dermal fillers available on the market today has been delineated by current literature, and that filling agents currently available have been refined to maximize…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Archives of Neurology Study Highlights Patients with aspirin resistance are more likely to sustain a more severe stroke than patients without aspirin resistance, according to a study of 90 patients with acute stroke who previously received aspirin therapy (Online First). A genetic case-control association study…

Study Examines Surgical Outcomes after Head and Neck Cancer at Safety-Net Hospitals

  EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact corresponding author Christine G. Gourin, M.D., M.P.H., call David March at 410-955-1534 or email dmarch1@jhmi.edu. CHICAGO – Safety-net hospitals appear to provide head and neck cancer surgical care to a vulnerable population, without an increase in short-term mortality, morbidity, or…

Archives of Otolaryngology–Head & Neck Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Archives of Otolaryngology–Head & Neck Surgery Study Highlights Safety-net hospitals appear to provide head and neck cancer surgical care to a vulnerable population, without an increase in short-term mortality, morbidity, or costs (See news release below). Many patients with head and neck cancer experience pain…

Children with Psoriasis May be at Increased Risk for Overweight and Obesity

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact Amy S. Paller, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – A study of children in nine countries found that psoriasis in children was associated with an increased risk for overweight and obesity, regardless of psoriasis severity, according…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012  Archives of Dermatology Study Highlights A study of children from nine countries found that psoriasis in children was associated with an increased risk for overweight and obesity, regardless of psoriasis severity (Online First; see news release below). A questionnaire-based study of 1,541 adults with vitiligo…

Chronic Pain in Parents Appears Associated with Chronic Pain in Adolescents, Young Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact Gry B. Hoftun, M.D., email gry.b.hoftun@ntnu.no. To contact editorial corresponding author Tonya M. Palermo, Ph.D., call Liz Hunter at 206-616-3192 or email elh415@uw.edu. CHICAGO– Chronic pain in parents appears to be associated with chronic nonspecific pain and chronic multisite pain in…

Study Examines Postdischarge Complications After General Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact Julie A. Sosa, M.D., M.A., call Helen Dodson at 203-436-3984 or email helen.dodson@yale.edu. To contact critique author Desmond C. Winter, M.D., email des.winter@gmail.com. An author podcast will be available on the journal website after the embargo lifts: http://bit.ly/JLp3jy CHICAGO – A…

Uninsured Patients Undergoing Craniotomy for Brain Tumor Have Higher In-Hospital Mortality

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact Alfredo Quiñones-Hinojosa, M.D., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. To contact critique corresponding author Shawn L. Hervey-Jumper, M.D., call Kara Gavin 734-764-2220 or email kegavin@umich.edu. CHICAGO – Compared to insured patients, uninsured patients have higher in-hospital mortality following surgery…

Archives of Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Archives of Surgery Study Highlights Compared to insured patients, uninsured patients have higher in-hospital mortality following surgery for brain tumors (See news release below). A study of postdischarge (PD) complications after general surgery procedures found that overall, 16.7 percent of patients experienced a complication and…

Unemployment May Be Associated With Increased Heart Attack Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact Matthew E. Dupre, Ph.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. To contact commentary author William T. Gallo, Ph.D., call Susan Konig at 212-772-4068 or email skonig@hunter.cuny.edu. CHICAGO – Unemployment, multiple job losses and short periods without work may be…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Archives of Internal Medicine Study Highlights Unemployment, multiple job losses and short periods without work may be associated with increased risk for acute myocardial infarction (AMI, heart attack) in a study that examined different dimensions of unemployment (Online First, see news release below). A study…

Study Suggests Repeat Testing Common Among Medicare Beneficiaries

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 19, 2012 Media Advisory: To contact H. Gilbert Welch, M.D., M.P.H., call Annmarie Christensen at 603-653-0897 or email annmarie.christensen@dartmouth.edu. To contact corresponding commentary author Arnold Milstein, M.D., M.P.H., call Margarita Gallardo at 650-723-7897 or email mjgallardo@stanford.edu. CHICAGO – A study suggests that diagnostic tests are frequently repeated…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Study Finds That Older Persons With Positive Age Stereotypes More Likely to Recover From Severe Disability “Little research has been conducted on factors that account for why some older persons recover from disability and others do not. We considered a new culture-based explanatory factor: age…

Citicoline Does Not Improve Functional, Cognitive Status in Patients with Traumatic Brain Injury

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Media Advisory: To contact Ross D. Zafonte, D.O., call Tim Sullivan at 617-573-2918 or email tsullivan11@partners.org. To contact editorial co-author Robert L. Ruff, M.D., Ph.D., call Jessica Studeny at 216-368-4692 or email jessica.studeny@case.edu. CHICAGO – Although approved for use for treating traumatic brain injury (TBI)…

Patients With Online Access to Clinicians, Medical Records Have Increased Use of Clinical Services

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 20, 2012 Media Advisory: To contact Ted E. Palen, M.D., Ph.D., M.S.P.H., call Amy Whited at 303-344-7518 or email Amy.L.Whited@kp.org. To contact editorial co-author David W. Bates, M.D., M.Sc., call Lori Schroth at 617-534-1604 or email Ljshanks@partners.org. CHICAGO – Patients with online access to their medical records…

Dance Intervention Improves Self-Rated Health of Girls With Internalizing Problems

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 12, 2012 Media Advisory: To contact Anna Duberg, R.P.T., email anna.duberg2@orebroll.se. CHICAGO– A dance intervention program improved the self-rated health of Swedish girls with internalizing problems, such as stress and psychosomatic symptoms, according to a report of a study published Online First by Archives of Pediatrics &…

Fasting Time Prior to Blood Lipid Tests Appears to Have Limited Association With Lipid Levels

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 12, 2012 Media Advisory: To contact Christopher Naugler, M.Sc., M.D., C.C.F.P., F.C.F.P., F.R.C.P.C., call Marta Cyperling at 403-210-3835 or email marta.cyperling@ucalgary.ca. To contact editorial author J. Michael Gaziano, M.D., M.P.H., and commentary corresponding author Samia Mora, M.D., M.H.S., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 12, 2012 Archives of Internal Medicine Study Highlights Fasting prior to blood lipid tests appears to have limited association with lipid subclass levels, suggesting that fasting for routine lipid level determinations may be unnecessary (Online First, see news release below). A review of electronic health records of…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 12, 2012 Archives of General Psychiatry Study Highlights A study that measured the fecundity (the ability to reproduce) of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa or substance abuse and their unaffected siblings compared with the general population suggests that except for women with depression,…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Study Examines Brain White Matter Changes in Soccer Players “Soccer is the most popular sport in the world, with more than 250 million active players. It is the only sport in which the unprotected head is a primary point of contact when heading the ball….

Genetic Variation May Modify Associations Between Low Vitamin D Levels and Adverse Health Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Media Advisory: To contact Gregory P. Levin, Ph.D., call Leila Gray at 206-685-0381 or email leilag@u.washington.edu. CHICAGO – Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such…

Having Migraines Associated With Higher Incidence of Brain Lesions Among Women; Effect on Health Uncertain

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, NOVEMBER 13, 2012 Media Advisory: To contact corresponding author Mark C. Kruit, M.D., Ph.D., email m.c.kruit@lumc.nl. To contact editorial co-author Deborah I. Friedman, M.D., M.P.H., call Jeff Carlton at 214-648-2876 or email Jeffrey.Carlton@utsouthwestern.edu. CHICAGO – After nearly 10 years of follow-up of study participants who experienced migraines and…

Study Examines Genetics, Incidence of Age-Related Macular Degeneration

EMBARGOED FOR RELEASE: 10 A.M. (CT), FRIDAY, NOVEMBER 9, 2012 Media Advisory: To contact Ronald Klein, M.D., M.P.H., call Susan Smith at 608-262-7335 or email ssmith5@uwhealth.org. An author podcast will be available on the journal website after the embargo lifts: http://bitly.com/QGSWAs CHICAGO – A report that describes the relationship of age and risk alleles (variant…

Patients With HBV-Related Liver Cancer Who Receive Antiviral Therapy Have Lower Risk of Tumor Recurrence

EMBARGOED FOR EARLY RELEASE: 2:45 P.M. (CT) MONDAY, NOVEMBER 12, 2012 Media Advisory: To contact Chun-Ying Wu, M.D., Ph.D., M.P.H., email chun@vghtc.gov.tw. To contact editorial author Anna S. F. Lok, M.D., call Nicole Fawcett at 734-764-2220 or email nfawcett@umich.edu. CHICAGO – Patients with hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC; liver cancer) who received nucleoside…

Study Examines Effect of Timing of Cell Therapy Following Heart Attack

FOR RELEASE: 2 P.M. (CT) MONDAY, NOVEMBER 5, 2012 Jay H. Traverse, M.D., of the Minneapolis Heart Institute at Abbott Northwestern Hospital, Minneapolis, and colleagues investigated the influence of timing of cardiovascular cell delivery within the first week after a heart attack on improving left ventricular (LV) function following reperfusion. “Cell therapy may eventually become…

Study Evaluates Mesenchymal Stem Cell Therapies for Cardiac Patients

FOR RELEASE: 2 P.M. (CT) MONDAY, NOVEMBER 5, 2012 Joshua M. Hare, M.D., of the University of Miami Miller School of Medicine, and colleagues conducted a study to examine whether allogeneic (taken from a different individual) mesenchymal stem cells (MSCs) are as safe and effective as autologous (donor and recipient are the same person) MSCs…

Patients Who Cannot Tolerate Statins Achieve Reduction in LDL Cholesterol Levels With Administration of Monoclonal Antibody

EMBARGOED FOR EARLY RELEASE: 12:45 P.M. (CT) MONDAY, NOVEMBER 5, 2012 David Sullivan, M.D., of the Royal Prince Alfred Hospital, Camperdown, Australia, and colleagues conducted a phase 2 study to assess the efficacy and safety of subcutaneous (under the skin) administration of a human monoclonal antibody to the protein PCSK9, (the product is designated AMG145),…

Pre-Operative and Post-Operative Fish Oil Supplementation Does Not Appear Effective in Reducing Atrial Fibrillation Following Heart Surgery

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact corresponding author Dariush Mozaffarian, M.D., Dr.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact corresponding author Roberto Marchioli, M.D., email marchioli@negrisud.it.   CHICAGO – Among patients undergoing cardiac surgery, supplementation with a n-3-polyunsaturated fatty acid (fish oil) before…

Comparison of Anti-Clotting Drugs Finds Differences in Platelet Reactivity, Similar Clinical Outcomes

EMBARGOED FOR EARLY RELEASE: 5:30 P.M. (CT) SUNDAY, NOVEMBER 4, 2012 Paul A. Gurbel, M.D., of the Sinai Center for Thrombosis Research, Baltimore, and colleagues conducted a study to examine the differences in platelet reactivity and clinical outcomes among patients with acute coronary syndromes (ACS) being treated by the antiplatelet agents clopidogrel or prasugrel. From…

Study Finds High Prevalence of Major Cardiovascular Disease Risk Factors Among U.S. Hispanic/Latino Adults

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact Martha L. Daviglus, M.D., Ph.D., call Jeanne Galatzer-Levy at 312-996-1583 or email jgala@uic.edu. CHICAGO – In a study that involved more than 16,000 Hispanic/Latino men and women living in the United States, the prevalence of major cardiovascular disease (CVD) risk…

Other Studies Appearing in JAMA

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Use of Corticosteroid During Cardiac Surgery Does Not Appear to Improve Outcomes Jan M. Dieleman, M.D., of the University Medical Center, Utrecht, the Netherlands and colleagues conducted a randomized clinical trial to quantify the effect of a single intraoperative dose of the corticosteroid dexamethasone…

Risk of Fatal Coronary Heart Disease Higher Among Black Men and Women

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact Monika M. Safford, M.D., call Jennifer Park Lollar at 205-934-3888 or email jpark@uab.edu. To contact editorial author Michael S. Lauer, M.D., call the NHLBI Office of Communications at 301-496-4236 or email nhlbi_news@nhlbi.nih.gov. CHICAGO – In an examination of the incidence…

Daily Multivitamin Use Among Men Does Not Reduce Risk of Major Cardiovascular Events

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact Howard D. Sesso, Sc.D., M.P.H., call Tom Langford at 617-534-1605 or email tlangford@partners.org. To contact Eva M. Lonn, M.D., M.Sc., call Veronica McGuire at 905-525-9140, ext. 22169; or email vmcguir@mcmaster.ca. CHICAGO – In a randomized study that included nearly 15,000…

Lifetime Risk of Developing Cardiovascular Disease Substantial

EMBARGOED FOR EARLY RELEASE: 11 A.M. (CT) MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact John T. Wilkins, M.D., M.S., call Erin White at 847-491-4888 or email ewhite@northwestern.edu. CHICAGO – Even in men and women with an optimal cardiovascular disease (CVD) risk factor profile, the lifetime risk estimate for CVD is greater than 30 percent,…

Study Examines Smoking by Inpatients During Hospital Stay

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact author Susan Regan, Ph.D., call Ryan Donovan at 617-724-6433 or email rcdonovan@partners.org. To contact commentary author Steven A. Schroeder, M.D., call Elizabeth Fernandez at 415-514-1592 or email Elizabeth.Fernandez@ucsf.edu. CHICAGO– A study of smokers admitted to a large urban teaching hospital in…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 5, 2012 Archives of General Psychiatry Study Highlights A study of 158 soldiers that tested whether soldiers’ emotional reactivity to enriched CO2 inhalation before deployment would predict their psychological adjustment while deployed in Iraq suggests that the presence of predeployment emotional reactivity potentiated (enhanced) the effects of…

Physical Exercise Improves Gait Speed, Muscle Strength, Fitness in Patients with Parkinson Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact study author Lisa M. Shulman, M.D., call Sharon Boston at 410-328-8919 or email sboston@umm.edu. To contact corresponding editorial author E. Ray Dorsey, M.D., M.B.A., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. CHICAGO – Physical exercise, including treadmill, stretching and resistance…

Eating at Fast-Food, Full-Service Restaurants Associated With Increased Calorie Intake

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, NOVEMBER 5, 2012 Media Advisory: To contact Lisa M. Powell, Ph.D., call Sherri McGinnis Gonzalez at 312-996-8277 or email smcginn@uic.edu. An author podcast will be available on the journal website after the embargo lifts: http://bit.ly/PogxGc CHICAGO – Eating meals and other foods from fast-food and full-service restaurants appears…

Regardless of Age, Measures of Kidney Function Remain Predictors of Kidney Disease and Death

EMBARGOED FOR EARLY RELEASE: 2:00 P.M. (CT) TUESDAY, OCTOBER 30, 2012 Media Advisory: To contact corresponding author Josef Coresh, M.D., Ph.D., call Tim Parsons at 410-955-7619 or email tmparson@jhsph.edu. To contact editorial author Ian H. de Boer, M.D., M.S., call Clare LaFond at 206-685-1323 or email clareh@uw.edu. CHICAGO – In a large, collaborative study that…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Archives of General Psychiatry Study Highlights A report on two studies in Ireland suggests that psychotic symptoms are associated with increased risk for suicidal behavior in the general adolescent population and in adolescents with psychiatric disorder. The results indicate that psychotic symptoms were associated with…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights Behavioral treatment for obesity was associated with positive outcomes among moderately and severely obese children when initiated early in life, but treatment was not associated with beneficial effects for adolescents (those age 14 to 16 years) with…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Archives of Neurology Study Highlights A study of children with sickle cell anemia (SCA) screened by magnetic resonance imaging (MRI) for participation in a randomized controlled trial found that acute silent cerebral ischemic (a temporary shortage of oxygen caused by reduced blood flow) events were…

Overweight, Obesity in Adolescents Appears Associated with Increased Risk for End-Stage Renal Disease Over Time

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Media Advisory: To contact author Asaf Vivante, M.D., email asafvivante@gmail.com. To contact commentary author Kirsten L. Johansen, M.D., call Jason Bardi at 415-502-4608 or email jason.bardi@ucsf.edu. CHICAGO– Being overweight and obese during adolescence appears related to an increased risk of all-cause treated end-stage renal disease…

Decline in Incidence of Heart Attacks Appears Associated with Smoke-Free Workplace Laws

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Media Advisory: To contact author Richard D. Hurt, M.D., call Kelley Luckstein at 507-538-5554 or email luckstein.kelley@mayo.edu. To contact commentary author Pamela M. Ling, M.D., M.P.H., call Jason Bardi at 415-502-4608 or email jason.bardi@ucsf.edu. CHICAGO– A decline in the incidence of myocardial infarction (MI, heart…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 29, 2012 Archives of Internal Medicine Study Highlights Being overweight and obese during adolescence appears related to an increased risk of all-cause treated end-stage renal disease (ESRD) during a 25-year period (Online First, see news release below). A decline in the incidence of myocardial infarction (MI, heart…

Early Surgical Treatment of Low-Grade Glioma Brain Tumor Associated With Better Survival Than Watchful Waiting

EMBARGOED FOR EARLY RELEASE: 6:15 A.M. (CT) THURSDAY, OCTOBER 25, 2012 Media Advisory: To contact Asgeir S. Jakola, M.D., email asgeir.s.jakola@ntnu.no. To contact editorial author James M. Markert, M.D., call Bob Shepard at 205-934-8934 or email bshep@uab.edu. CHICAGO – In a comparison of strategies for treating low-grade gliomas (brain tumors), patients in Norway treated at…

Also Appearing in This Week’s Issue

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 23, 2012 Molecular Prognostic Assay May Help Identify Patients at High Risk of Death Despite Small, Node-Negative Lung Tumors “Low-dose computed tomography screening may increase diagnoses of T1a node-negative non-small-cell lung cancers (NSCLC). One-quarter of these patients die within 5 years. Maximizing the benefit of screening requires…

Use of Mechanical Ventilation At Lower Level Among Patients Without Lung Injury Associated With Better Clinical Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 23, 2012 Media Advisory: To contact Ary Serpa Neto, M.D., M.Sc., email aryserpa@terra.com.br. To contact editorial author Niall D. Ferguson, M.D., M.Sc., call Leslie O’Leary at 416-586-4800, ext.8306; or email lo’leary2@mtsinai.on.ca. CHICAGO –Among patients without acute respiratory distress syndrome, protective mechanical ventilation with use of lower tidal…

Most Large Treatment Effects of Medical Interventions Come From Small Studies

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 23, 2012 Media Advisory: To contact corresponding author John P. A. Ioannidis, M.D., D.Sc., call Krista Conger at 650-725-5371 or email kristac@stanford.edu. To contact editorial author Andrew D. Oxman, M.D., email oxman@online.no. CHICAGO – In an examination of the characteristics of studies that yield large treatment effects…

Men With Certain Cardiovascular Risk Factors Appear to be At Increased Risk of Peripheral Artery Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 23, 2012 Media Advisory: To contact Michel M. Joosten, Ph.D., call Kelly Lawman at 617-667-7305 or email klawman@bidmc.harvard.edu. CHICAGO – Among nearly 45,000 men who were followed up for more than two decades, those with the risk factors of smoking, hypertension, high cholesterol, and type 2 diabetes…

Study of Patients Ages 90 and Older Links Poor Physical Performance, Increased Odds of Dementia

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 22, 2012 Media Advisory: To contact study authors call Tom Vasich at 949-824-6455 or email tmvasich@uci.edu.  CHICAGO– Poor physical performance on activities including walking was associated with increased odds of dementia in a study of individuals 90 years and older, according to a report published Online First…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 22, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights An increased risk of suicidal ideation (thoughts of harming or killing oneself) in adolescents appears to be associated with recent victimization, such as by peers, sexual assault, and maltreatment (Online First, see news release below). A study…

Increased Risk of Suicidal Thoughts Among Adolescents Appears Related to Recent Victimization

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 22, 2012 Media Advisory: To contact Heather A. Turner, Ph.D., call Erika Mantz at 603-862-1567 or email erika.mantz@unh.edu.  CHICAGO– An increased risk of suicidal ideation (thoughts of harming or killing oneself) in adolescents appears to be associated with recent victimization, such as by peers, sexual assault, and…

Eating More Legumes May Improve Glycemic Control, Lower Estimated Heart Disease Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 22, 2012 Media Advisory: To contact author David J.A. Jenkins, M.D., call Kate Taylor at 416-864-6060 ext. 6537 or email taylorka@smh.ca. To contact commentary author Marion J. Franz, M.S., R.D., C.D.E., call 952-941-6751 or email MarionFranz@aol.com. CHICAGO – Eating more legumes (such as beans, chickpeas or lentils)…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 22, 2012 Archives of Internal Medicine Study Highlights Eating more legumes (such as beans, chickpeas or lentils) as part of a low-glycemic index diet appears to improve glycemic control and reduce estimated coronary heart disease risk in patients with type 2 diabetes mellitus (Online First, see news…

Daily Sedation Interruption For Critically Ill Patients Does Not Improve Outcomes or Reduce Use of Mechanical Ventilation

EMBARGOED FOR EARLY RELEASE: 8:15 A.M. (CT) WEDNESDAY, OCTOBER 17, 2012 Media Advisory: To contact Sangeeta Mehta, M.D., call Nicole Bodnar at 416-978-5811 or email Nicole.bodnar@utoronto.ca. CHICAGO – For critically ill patients receiving mechanical ventilation, daily sedation interruption did not reduce the duration of mechanical ventilation or appear to offer any benefit to patients, and…

Tight Glucose Control For Critically Ill Children Does Not Appear to Impair Neurocognitive Development

EMBARGOED FOR EARLY RELEASE: 8:15 A.M. (CT) WEDNESDAY, OCTOBER 17, 2012 Media Advisory: To contact corresponding author Greet Van den Berghe, M.D., Ph.D., email greet.vandenberghe@med.kuleuven.be. To contact editorial author Robert C. Tasker, M.B.B.S., M.D., call Keri Stedman at 617-919-3114 or email keri.stedman@childrens.harvard.edu. CHICAGO – Although there is some concern that hypoglycemia may adversely affect the…