JAMA Report Videos

The following are JAMA Report videos made publicly available once the related article in JAMA has published.

  • April 18, 2017

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat”

    TRT: 1:47

    INTRO: SORE THROAT IS A COMMON SYMPTOM THAT SENDS PATIENTS TO THEIR DOCTORS, WHO OFTEN PRESCRIBE ANTIBIOTICS WHEN THEY WON’T HELP AND AREN’T NEEDED. FINDING ALTERNATIVE STRATEGIES TO RELIEVE SORE THROAT SYMPTOMS AND REDUCE ANTIBIOTIC USE IS IMPORTANT. A NEW STUDY IN JAMA INVESTIGATES WHETHER A CORTICOSTEROID PILL RESOLVES SORE THROAT SYMPTOMS IN ADULTS WHO DON’T REQUIRE ANTIBIOTICS. LAURA BERGER HAS MORE IN THIS WEEK’S JAMA REPORT.

    AUDIO:

    VO:

     PATIENTS IN THE U.S. MADE 92 MILLION VISITS TO DOCTORS FOR SORE THROATS BETWEEN 1997 AND 2010. MANY OF THOSE PATIENTS RECEIVED UNNECESSARY ANTIBIOTICS.

    (B-ROLL: doctor checking patient’s throat)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 11

    Runs: 14

    “We know the more antibiotics that we take, the more likely we are to develop infections which are resistant to antibiotics in the future. So it’s important to try and find alternative treatments…we wanted to know if steroids could be an alternative treatment for sore throat.”

    AUDIO:

    VO:

    1. GAIL HAYWARD OF THE UNIVERSITY OF OXFORD AND HER COLLEAGUES STUDIED ALMOST 600 ADULTS WITH SORE THROATS WHO DIDN’T REQUIRE IMMEDIATE ANTIBIOTICS FROM CLINICS IN ENGLAND AS PART OF A RANDOMIZED TRIAL. HALF THE PATIENTS TOOK A 10-MILLIGRAM DOSE OF THE CORTICOSTEROID DEXAMETHASONE WHILE THE OTHER HALF RECEIVED A PLACEBO.

    THE RESEARCHERS THEN MEASURED WHETHER SORE THROAT SYMPTOMS WERE COMPLETELY RESOLVED AFTER ONE OR TWO DAYS.

    THE STUDY APPEARS IN JAMA, THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

    (B-ROLL: Dr. Hayward walking down hallway, working on computer, patient getting throat exam, shot of dexamethasone, patient exam)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 53

    Runs: 17

    “After 24 hours, we didn’t see any difference in the proportion of patients who felt better between those taking the steroid and those taking the placebo. However, at 48 hours we did see a difference, more patients in the group that took the steroid tablet felt completely better, than patients in the placebo group.”

    VO: ALTHOUGH MORE PATIENTS WHO TOOK THE STEROID FELT COMPLETELY BETTER AFTER 48 HOURS, DR. HAYWARD SAYS THERE ARE MANY DOWNSIDES TO TAKING STEROIDS, INCLUDING DIFFICULTY SLEEPING, ACID REFLUX, AND INCREASED APPETITE.

    (B ROLL: Doctor checking patient’s ears, talking to patient, shot of drug)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 1:23

    Runs: 23

    “We think that although steroids are probably not ideal to be used in primary care for all patients presenting with sore throat, what our study couldn’t really do is look at those patients with very severe sore throat. We think that its possible that in very severe sore throat steroids might help patients be able to swallow fluids and medication, and avoid needing to go to hospital which could be very beneficial, but this research has not yet been done.​”

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: Doctor using tongue depressor on patient)

    TAG: THE STUDY STARTED IN 2013 AND ENDED IN 2015.

  • March 28, 2017

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Celiac disease is intolerance to gluten, a protein complex found in wheat and some other grains.  When people with celiac disease eat foods with gluten their immune response damages the lining of the small intestine, causing gastrointestinal and other symptoms.

    The selection of gluten-free foods in the grocery store is proof enough that many people worry they might have celiac disease, but should doctors be screening people for it?

    Remember, screening means looking for disease in people without symptoms or signs of it;

    Screening for celiac disease typically involves drawing blood for serum antibody levels and following up with an intestinal biopsy.

    The United States Preventive Services Task Force, an independent volunteer panel of national experts in prevention and evidence-based medicine, has now reviewed the literature and concludes that we don’t have enough information to know.

    Some groups still recommend screening higher risk patients for celiac disease, but the Task Force says there are simply no good studies demonstrating the accuracy of testing in asymptomatic populations, or the benefits and harms of early detection and treatment of screen-detected disease.

    So if your patients’ main symptom is anxiety about gluten sensitivity or celiac disease, you’re probably OK holding off on testing, unless other symptoms raise suspicions for the disorder. And if you do screen, patients should understand that the balance of benefit and harm is uncertain.

    Thanks for listening, hope to see you soon and don’t forget to click the link in the description to read the entire recommendation statement.

  • February 21, 2017

    The Effects of Testosterone Gel on Health Outcomes

    The Effects of Testosterone Gel on Health Outcomes

    INTRO: Can testosterone gel improve memory, correct anemia, increase bone density or prevent the growth of coronary artery plaque in older men with low testosterone levels? Four new studies in JAMA and JAMA Internal Medicine found improvement in some of these measures.  Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

     

    LOW TESTOSTERONE LEVELS ARE COMMON IN OLDER MEN. FOUR NEW STUDIES IN JAMA AND JAMA INTERNAL MEDICINE LOOKED AT WHETHER USING A TESTOSTERONE GEL COULD AFFECT CERTAIN HEALTH OUTCOMES.

     

    (B-ROLL:

    Men working out on a track, and stretching, Close-up of testosterone gel, walking on track)

     

     

    AUDIO:

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@: 12

    Runs: 19

     

    “We selected men over 65 who had low testosterone levels. We treated them with either testosterone or placebo for one year.  We studied their blood counts, their bone density, the amount of plaque in their coronary arteries, and their memory.”

     

     

     

    AUDIO:

    VO:

     

    THE WORK BY DR. PETER SNYDER OF THE UNIVERSITY OF PENNSYLVANIA AND HIS CO-AUTHORS WAS PART OF A GROUP OF COORDINATED TRIALS ON THE EFFECTS OF TESTOSTERONE GEL IN OLDER MEN WITH LOW TESTOSTERONE LEVELS.

     

    RESEARCHERS FOUND THE TESTOSTERONE GEL CORRECTED ANEMIA AND INCREASED BONE DENSITY MORE THAN PLACEBO, BUT IT DID NOT IMPROVE MEMORY AND IT INCREASED THE AMOUNT OF CORONARY ARTERY PLAQUE.

     

    1. SNYDER SAYS THAT THE INCREASE IN THE AMOUNT OF CORONARY ARTERY PLAQUE COULD BE AN EARLY SIGN OF INCREASED RISK OF HEART PROBLEMS. AND THE STUDIES DID NOT LOOK AT PROSTATE CANCER, WHICH CAN GROW IN RESPONSE TO TESTOSTERONE.

     

    (B-ROLL: Dr. Snyder walking down the hall, on the phone, working on computer, Testosterone gel bottle, doctor with gel and patient, men stretching at gym, man on computer, picture of artery, bottle of testosterone gel)

     

    AUDIO

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@ 1:04

    Runs: 17

     

    “The next step is to conduct a much larger and longer trial say of 5,000 men for 5 years to determine if testosterone increases the risk of heart attack or increases the risk of prostate cancer. Or if it reduces the risk of bone fracture.”

     

     

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: men walking on a track)

     

    TAG: THE TESTOSTERONE TRIALS WERE CONDUCTED FROM 2010 TO 2014.

  • January 30, 2017

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    INTRO: Can brain-stimulating activities help older adults lower their risk of developing mild cognitive impairment? A new study in JAMA Neurology suggests certain activities may be associated with less risk. Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

    MILD COGNITIVE IMPAIRMENT OR MCI IS THE INTERMEDIATE STAGE BETWEEN NORMAL AGING AND DEMENTIA.

     

     

    (B-roll: woman working at a computer)

     

     

    SOT/FULL

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:8

    Runs:16

     

    “The frequency of MCI, depends on age. If you take a person 70 year and older, for example in our study, we have observed that the frequency or prevalence of MCI is about 15%.”

     

    AUDIO:

    VO:

     

    1. YONAS GEDA (GAY-da) OF THE MAYO CLINIC IN SCOTTSDALE, ARIZONA AND CO-AUTHORS STUDIED ALMOST 2 THOUSAND COGNITIVELY NORMAL ADULTS 70 AND OLDER TO SEE IF ENGAGING IN MENTALLY STIMULATING ACTVITIES WAS ASSOCIATED WITH DECREASED RISK FOR DEVELOPING MCI.

     

    THE OLDER ADULTS WERE FROM A MAYO CLINIC STUDY OF AGING IN MINNESOTA. THEY COMPLETED QUESTIONNAIRES ABOUT THEIR ACTIVITIES AND UNDERWENT ASSESSMENTS, INCLUDING FOR MEMORY. 

     

    RESEARCHERS FOUND PLAYING GAMES, CRAFTING, USING A COMPUTER AND SOCIAL ACTIVITIES WERE ASSOCIATED WITH DECREASED RISK OF MCI.

     

     

     

    (B-ROLL:

    Dr. walking with a woman, looking at data, man on I-pad, woman doing a puzzle, man on I-pad, woman with doctor)

     

    AUDIO:

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:49

    Runs:15

    SOT/FULL

     

    “This study is very important because dementia, MCI, these conditions are really common as we get older. We need to find out non-pharmacological approach to decrease the risk of MCI or dementia.”

     

    LAURA BERGER, THE JAMA REPORT

    (BROLL: woman doing a puzzle)

     

         TAG:THE STUDY LOOKED AT DATA FROM APRIL 2006 TO JUNE 2016.

     

  • April 18, 2017

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat”

    TRT: 1:47

    INTRO: SORE THROAT IS A COMMON SYMPTOM THAT SENDS PATIENTS TO THEIR DOCTORS, WHO OFTEN PRESCRIBE ANTIBIOTICS WHEN THEY WON’T HELP AND AREN’T NEEDED. FINDING ALTERNATIVE STRATEGIES TO RELIEVE SORE THROAT SYMPTOMS AND REDUCE ANTIBIOTIC USE IS IMPORTANT. A NEW STUDY IN JAMA INVESTIGATES WHETHER A CORTICOSTEROID PILL RESOLVES SORE THROAT SYMPTOMS IN ADULTS WHO DON’T REQUIRE ANTIBIOTICS. LAURA BERGER HAS MORE IN THIS WEEK’S JAMA REPORT.

    AUDIO:

    VO:

     PATIENTS IN THE U.S. MADE 92 MILLION VISITS TO DOCTORS FOR SORE THROATS BETWEEN 1997 AND 2010. MANY OF THOSE PATIENTS RECEIVED UNNECESSARY ANTIBIOTICS.

    (B-ROLL: doctor checking patient’s throat)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 11

    Runs: 14

    “We know the more antibiotics that we take, the more likely we are to develop infections which are resistant to antibiotics in the future. So it’s important to try and find alternative treatments…we wanted to know if steroids could be an alternative treatment for sore throat.”

    AUDIO:

    VO:

    1. GAIL HAYWARD OF THE UNIVERSITY OF OXFORD AND HER COLLEAGUES STUDIED ALMOST 600 ADULTS WITH SORE THROATS WHO DIDN’T REQUIRE IMMEDIATE ANTIBIOTICS FROM CLINICS IN ENGLAND AS PART OF A RANDOMIZED TRIAL. HALF THE PATIENTS TOOK A 10-MILLIGRAM DOSE OF THE CORTICOSTEROID DEXAMETHASONE WHILE THE OTHER HALF RECEIVED A PLACEBO.

    THE RESEARCHERS THEN MEASURED WHETHER SORE THROAT SYMPTOMS WERE COMPLETELY RESOLVED AFTER ONE OR TWO DAYS.

    THE STUDY APPEARS IN JAMA, THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

    (B-ROLL: Dr. Hayward walking down hallway, working on computer, patient getting throat exam, shot of dexamethasone, patient exam)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 53

    Runs: 17

    “After 24 hours, we didn’t see any difference in the proportion of patients who felt better between those taking the steroid and those taking the placebo. However, at 48 hours we did see a difference, more patients in the group that took the steroid tablet felt completely better, than patients in the placebo group.”

    VO: ALTHOUGH MORE PATIENTS WHO TOOK THE STEROID FELT COMPLETELY BETTER AFTER 48 HOURS, DR. HAYWARD SAYS THERE ARE MANY DOWNSIDES TO TAKING STEROIDS, INCLUDING DIFFICULTY SLEEPING, ACID REFLUX, AND INCREASED APPETITE.

    (B ROLL: Doctor checking patient’s ears, talking to patient, shot of drug)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 1:23

    Runs: 23

    “We think that although steroids are probably not ideal to be used in primary care for all patients presenting with sore throat, what our study couldn’t really do is look at those patients with very severe sore throat. We think that its possible that in very severe sore throat steroids might help patients be able to swallow fluids and medication, and avoid needing to go to hospital which could be very beneficial, but this research has not yet been done.​”

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: Doctor using tongue depressor on patient)

    TAG: THE STUDY STARTED IN 2013 AND ENDED IN 2015.

  • March 28, 2017

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Celiac disease is intolerance to gluten, a protein complex found in wheat and some other grains.  When people with celiac disease eat foods with gluten their immune response damages the lining of the small intestine, causing gastrointestinal and other symptoms.

    The selection of gluten-free foods in the grocery store is proof enough that many people worry they might have celiac disease, but should doctors be screening people for it?

    Remember, screening means looking for disease in people without symptoms or signs of it;

    Screening for celiac disease typically involves drawing blood for serum antibody levels and following up with an intestinal biopsy.

    The United States Preventive Services Task Force, an independent volunteer panel of national experts in prevention and evidence-based medicine, has now reviewed the literature and concludes that we don’t have enough information to know.

    Some groups still recommend screening higher risk patients for celiac disease, but the Task Force says there are simply no good studies demonstrating the accuracy of testing in asymptomatic populations, or the benefits and harms of early detection and treatment of screen-detected disease.

    So if your patients’ main symptom is anxiety about gluten sensitivity or celiac disease, you’re probably OK holding off on testing, unless other symptoms raise suspicions for the disorder. And if you do screen, patients should understand that the balance of benefit and harm is uncertain.

    Thanks for listening, hope to see you soon and don’t forget to click the link in the description to read the entire recommendation statement.

  • February 21, 2017

    The Effects of Testosterone Gel on Health Outcomes

    The Effects of Testosterone Gel on Health Outcomes

    INTRO: Can testosterone gel improve memory, correct anemia, increase bone density or prevent the growth of coronary artery plaque in older men with low testosterone levels? Four new studies in JAMA and JAMA Internal Medicine found improvement in some of these measures.  Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

     

    LOW TESTOSTERONE LEVELS ARE COMMON IN OLDER MEN. FOUR NEW STUDIES IN JAMA AND JAMA INTERNAL MEDICINE LOOKED AT WHETHER USING A TESTOSTERONE GEL COULD AFFECT CERTAIN HEALTH OUTCOMES.

     

    (B-ROLL:

    Men working out on a track, and stretching, Close-up of testosterone gel, walking on track)

     

     

    AUDIO:

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@: 12

    Runs: 19

     

    “We selected men over 65 who had low testosterone levels. We treated them with either testosterone or placebo for one year.  We studied their blood counts, their bone density, the amount of plaque in their coronary arteries, and their memory.”

     

     

     

    AUDIO:

    VO:

     

    THE WORK BY DR. PETER SNYDER OF THE UNIVERSITY OF PENNSYLVANIA AND HIS CO-AUTHORS WAS PART OF A GROUP OF COORDINATED TRIALS ON THE EFFECTS OF TESTOSTERONE GEL IN OLDER MEN WITH LOW TESTOSTERONE LEVELS.

     

    RESEARCHERS FOUND THE TESTOSTERONE GEL CORRECTED ANEMIA AND INCREASED BONE DENSITY MORE THAN PLACEBO, BUT IT DID NOT IMPROVE MEMORY AND IT INCREASED THE AMOUNT OF CORONARY ARTERY PLAQUE.

     

    1. SNYDER SAYS THAT THE INCREASE IN THE AMOUNT OF CORONARY ARTERY PLAQUE COULD BE AN EARLY SIGN OF INCREASED RISK OF HEART PROBLEMS. AND THE STUDIES DID NOT LOOK AT PROSTATE CANCER, WHICH CAN GROW IN RESPONSE TO TESTOSTERONE.

     

    (B-ROLL: Dr. Snyder walking down the hall, on the phone, working on computer, Testosterone gel bottle, doctor with gel and patient, men stretching at gym, man on computer, picture of artery, bottle of testosterone gel)

     

    AUDIO

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@ 1:04

    Runs: 17

     

    “The next step is to conduct a much larger and longer trial say of 5,000 men for 5 years to determine if testosterone increases the risk of heart attack or increases the risk of prostate cancer. Or if it reduces the risk of bone fracture.”

     

     

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: men walking on a track)

     

    TAG: THE TESTOSTERONE TRIALS WERE CONDUCTED FROM 2010 TO 2014.

  • January 30, 2017

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    INTRO: Can brain-stimulating activities help older adults lower their risk of developing mild cognitive impairment? A new study in JAMA Neurology suggests certain activities may be associated with less risk. Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

    MILD COGNITIVE IMPAIRMENT OR MCI IS THE INTERMEDIATE STAGE BETWEEN NORMAL AGING AND DEMENTIA.

     

     

    (B-roll: woman working at a computer)

     

     

    SOT/FULL

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:8

    Runs:16

     

    “The frequency of MCI, depends on age. If you take a person 70 year and older, for example in our study, we have observed that the frequency or prevalence of MCI is about 15%.”

     

    AUDIO:

    VO:

     

    1. YONAS GEDA (GAY-da) OF THE MAYO CLINIC IN SCOTTSDALE, ARIZONA AND CO-AUTHORS STUDIED ALMOST 2 THOUSAND COGNITIVELY NORMAL ADULTS 70 AND OLDER TO SEE IF ENGAGING IN MENTALLY STIMULATING ACTVITIES WAS ASSOCIATED WITH DECREASED RISK FOR DEVELOPING MCI.

     

    THE OLDER ADULTS WERE FROM A MAYO CLINIC STUDY OF AGING IN MINNESOTA. THEY COMPLETED QUESTIONNAIRES ABOUT THEIR ACTIVITIES AND UNDERWENT ASSESSMENTS, INCLUDING FOR MEMORY. 

     

    RESEARCHERS FOUND PLAYING GAMES, CRAFTING, USING A COMPUTER AND SOCIAL ACTIVITIES WERE ASSOCIATED WITH DECREASED RISK OF MCI.

     

     

     

    (B-ROLL:

    Dr. walking with a woman, looking at data, man on I-pad, woman doing a puzzle, man on I-pad, woman with doctor)

     

    AUDIO:

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:49

    Runs:15

    SOT/FULL

     

    “This study is very important because dementia, MCI, these conditions are really common as we get older. We need to find out non-pharmacological approach to decrease the risk of MCI or dementia.”

     

    LAURA BERGER, THE JAMA REPORT

    (BROLL: woman doing a puzzle)

     

         TAG:THE STUDY LOOKED AT DATA FROM APRIL 2006 TO JUNE 2016.

     

  • April 18, 2017

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat

    Study Examines Effectiveness of Steroid Medication for Sore Throat”

    TRT: 1:47

    INTRO: SORE THROAT IS A COMMON SYMPTOM THAT SENDS PATIENTS TO THEIR DOCTORS, WHO OFTEN PRESCRIBE ANTIBIOTICS WHEN THEY WON’T HELP AND AREN’T NEEDED. FINDING ALTERNATIVE STRATEGIES TO RELIEVE SORE THROAT SYMPTOMS AND REDUCE ANTIBIOTIC USE IS IMPORTANT. A NEW STUDY IN JAMA INVESTIGATES WHETHER A CORTICOSTEROID PILL RESOLVES SORE THROAT SYMPTOMS IN ADULTS WHO DON’T REQUIRE ANTIBIOTICS. LAURA BERGER HAS MORE IN THIS WEEK’S JAMA REPORT.

    AUDIO:

    VO:

     PATIENTS IN THE U.S. MADE 92 MILLION VISITS TO DOCTORS FOR SORE THROATS BETWEEN 1997 AND 2010. MANY OF THOSE PATIENTS RECEIVED UNNECESSARY ANTIBIOTICS.

    (B-ROLL: doctor checking patient’s throat)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 11

    Runs: 14

    “We know the more antibiotics that we take, the more likely we are to develop infections which are resistant to antibiotics in the future. So it’s important to try and find alternative treatments…we wanted to know if steroids could be an alternative treatment for sore throat.”

    AUDIO:

    VO:

    1. GAIL HAYWARD OF THE UNIVERSITY OF OXFORD AND HER COLLEAGUES STUDIED ALMOST 600 ADULTS WITH SORE THROATS WHO DIDN’T REQUIRE IMMEDIATE ANTIBIOTICS FROM CLINICS IN ENGLAND AS PART OF A RANDOMIZED TRIAL. HALF THE PATIENTS TOOK A 10-MILLIGRAM DOSE OF THE CORTICOSTEROID DEXAMETHASONE WHILE THE OTHER HALF RECEIVED A PLACEBO.

    THE RESEARCHERS THEN MEASURED WHETHER SORE THROAT SYMPTOMS WERE COMPLETELY RESOLVED AFTER ONE OR TWO DAYS.

    THE STUDY APPEARS IN JAMA, THE JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

    (B-ROLL: Dr. Hayward walking down hallway, working on computer, patient getting throat exam, shot of dexamethasone, patient exam)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 53

    Runs: 17

    “After 24 hours, we didn’t see any difference in the proportion of patients who felt better between those taking the steroid and those taking the placebo. However, at 48 hours we did see a difference, more patients in the group that took the steroid tablet felt completely better, than patients in the placebo group.”

    VO: ALTHOUGH MORE PATIENTS WHO TOOK THE STEROID FELT COMPLETELY BETTER AFTER 48 HOURS, DR. HAYWARD SAYS THERE ARE MANY DOWNSIDES TO TAKING STEROIDS, INCLUDING DIFFICULTY SLEEPING, ACID REFLUX, AND INCREASED APPETITE.

    (B ROLL: Doctor checking patient’s ears, talking to patient, shot of drug)

    AUDIO:

    SOT/FULL

    Gail Hayward, DPhil, MRCG, University of Oxford

    Super@: 1:23

    Runs: 23

    “We think that although steroids are probably not ideal to be used in primary care for all patients presenting with sore throat, what our study couldn’t really do is look at those patients with very severe sore throat. We think that its possible that in very severe sore throat steroids might help patients be able to swallow fluids and medication, and avoid needing to go to hospital which could be very beneficial, but this research has not yet been done.​”

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: Doctor using tongue depressor on patient)

    TAG: THE STUDY STARTED IN 2013 AND ENDED IN 2015.

  • March 28, 2017

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Screening for Celiac Disease: USPSTF Recommendation Statement

    Celiac disease is intolerance to gluten, a protein complex found in wheat and some other grains.  When people with celiac disease eat foods with gluten their immune response damages the lining of the small intestine, causing gastrointestinal and other symptoms.

    The selection of gluten-free foods in the grocery store is proof enough that many people worry they might have celiac disease, but should doctors be screening people for it?

    Remember, screening means looking for disease in people without symptoms or signs of it;

    Screening for celiac disease typically involves drawing blood for serum antibody levels and following up with an intestinal biopsy.

    The United States Preventive Services Task Force, an independent volunteer panel of national experts in prevention and evidence-based medicine, has now reviewed the literature and concludes that we don’t have enough information to know.

    Some groups still recommend screening higher risk patients for celiac disease, but the Task Force says there are simply no good studies demonstrating the accuracy of testing in asymptomatic populations, or the benefits and harms of early detection and treatment of screen-detected disease.

    So if your patients’ main symptom is anxiety about gluten sensitivity or celiac disease, you’re probably OK holding off on testing, unless other symptoms raise suspicions for the disorder. And if you do screen, patients should understand that the balance of benefit and harm is uncertain.

    Thanks for listening, hope to see you soon and don’t forget to click the link in the description to read the entire recommendation statement.

  • February 21, 2017

    The Effects of Testosterone Gel on Health Outcomes

    The Effects of Testosterone Gel on Health Outcomes

    INTRO: Can testosterone gel improve memory, correct anemia, increase bone density or prevent the growth of coronary artery plaque in older men with low testosterone levels? Four new studies in JAMA and JAMA Internal Medicine found improvement in some of these measures.  Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

     

    LOW TESTOSTERONE LEVELS ARE COMMON IN OLDER MEN. FOUR NEW STUDIES IN JAMA AND JAMA INTERNAL MEDICINE LOOKED AT WHETHER USING A TESTOSTERONE GEL COULD AFFECT CERTAIN HEALTH OUTCOMES.

     

    (B-ROLL:

    Men working out on a track, and stretching, Close-up of testosterone gel, walking on track)

     

     

    AUDIO:

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@: 12

    Runs: 19

     

    “We selected men over 65 who had low testosterone levels. We treated them with either testosterone or placebo for one year.  We studied their blood counts, their bone density, the amount of plaque in their coronary arteries, and their memory.”

     

     

     

    AUDIO:

    VO:

     

    THE WORK BY DR. PETER SNYDER OF THE UNIVERSITY OF PENNSYLVANIA AND HIS CO-AUTHORS WAS PART OF A GROUP OF COORDINATED TRIALS ON THE EFFECTS OF TESTOSTERONE GEL IN OLDER MEN WITH LOW TESTOSTERONE LEVELS.

     

    RESEARCHERS FOUND THE TESTOSTERONE GEL CORRECTED ANEMIA AND INCREASED BONE DENSITY MORE THAN PLACEBO, BUT IT DID NOT IMPROVE MEMORY AND IT INCREASED THE AMOUNT OF CORONARY ARTERY PLAQUE.

     

    1. SNYDER SAYS THAT THE INCREASE IN THE AMOUNT OF CORONARY ARTERY PLAQUE COULD BE AN EARLY SIGN OF INCREASED RISK OF HEART PROBLEMS. AND THE STUDIES DID NOT LOOK AT PROSTATE CANCER, WHICH CAN GROW IN RESPONSE TO TESTOSTERONE.

     

    (B-ROLL: Dr. Snyder walking down the hall, on the phone, working on computer, Testosterone gel bottle, doctor with gel and patient, men stretching at gym, man on computer, picture of artery, bottle of testosterone gel)

     

    AUDIO

    SOT/FULL

    Peter Snyder, MD, Professor of Medicine, University of Pennsylvania

    Super@ 1:04

    Runs: 17

     

    “The next step is to conduct a much larger and longer trial say of 5,000 men for 5 years to determine if testosterone increases the risk of heart attack or increases the risk of prostate cancer. Or if it reduces the risk of bone fracture.”

     

     

    VO:

    LAURA BERGER, THE JAMA REPORT

     

    (BROLL: men walking on a track)

     

    TAG: THE TESTOSTERONE TRIALS WERE CONDUCTED FROM 2010 TO 2014.

  • January 30, 2017

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    Mentally Stimulating Activities in Late Life and Risk of Mild Cognitive Impairment

    INTRO: Can brain-stimulating activities help older adults lower their risk of developing mild cognitive impairment? A new study in JAMA Neurology suggests certain activities may be associated with less risk. Laura Berger has more in this week’s JAMA Report.

     

    AUDIO:

    VO:

    MILD COGNITIVE IMPAIRMENT OR MCI IS THE INTERMEDIATE STAGE BETWEEN NORMAL AGING AND DEMENTIA.

     

     

    (B-roll: woman working at a computer)

     

     

    SOT/FULL

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:8

    Runs:16

     

    “The frequency of MCI, depends on age. If you take a person 70 year and older, for example in our study, we have observed that the frequency or prevalence of MCI is about 15%.”

     

    AUDIO:

    VO:

     

    1. YONAS GEDA (GAY-da) OF THE MAYO CLINIC IN SCOTTSDALE, ARIZONA AND CO-AUTHORS STUDIED ALMOST 2 THOUSAND COGNITIVELY NORMAL ADULTS 70 AND OLDER TO SEE IF ENGAGING IN MENTALLY STIMULATING ACTVITIES WAS ASSOCIATED WITH DECREASED RISK FOR DEVELOPING MCI.

     

    THE OLDER ADULTS WERE FROM A MAYO CLINIC STUDY OF AGING IN MINNESOTA. THEY COMPLETED QUESTIONNAIRES ABOUT THEIR ACTIVITIES AND UNDERWENT ASSESSMENTS, INCLUDING FOR MEMORY. 

     

    RESEARCHERS FOUND PLAYING GAMES, CRAFTING, USING A COMPUTER AND SOCIAL ACTIVITIES WERE ASSOCIATED WITH DECREASED RISK OF MCI.

     

     

     

    (B-ROLL:

    Dr. walking with a woman, looking at data, man on I-pad, woman doing a puzzle, man on I-pad, woman with doctor)

     

    AUDIO:

    Yonas Geda, MD, MSc, Professor of Neurology and Psychiatry, Mayo Clinic

    Super@:49

    Runs:15

    SOT/FULL

     

    “This study is very important because dementia, MCI, these conditions are really common as we get older. We need to find out non-pharmacological approach to decrease the risk of MCI or dementia.”

     

    LAURA BERGER, THE JAMA REPORT

    (BROLL: woman doing a puzzle)

     

         TAG:THE STUDY LOOKED AT DATA FROM APRIL 2006 TO JUNE 2016.