USPSTF Recommendation Statement on Vitamin D, Calcium Supplementation to Prevent Fractures



Media advisory: To contact the U.S. Preventive Services Task Force, email the Media Coordinator at or call 202-572-2044. The full report is available on the For The Media website.

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Bottom Line: The U.S. Preventive Services Task Force (USPSTF) concludes current scientific evidence is insufficient regarding the use of vitamin D and calcium, alone or in combination, to prevent fractures in men and premenopausal women. The USPSTF recommends against daily supplementation with 400 IU or less of vitamin D and 1,000 mg or less of calcium to prevent fractures in postmenopausal women. Current scientific evidence is insufficient regarding the use of vitamin D and calcium at doses greater than 400 IU of vitamin D and greater than 1,000 mg of calcium in postmenopausal women.

Background: The USPSTF routinely makes recommendations about the effectiveness of preventive care services. This latest recommendation statement is an update of the 2013 recommendation on vitamin D supplementation, with or without calcium, to prevent fractures.

The USPSTF Concludes:

Related material

The following related elements from The JAMA Network are also available on the For The Media website:

— A podcast interview with Alex H. Krist, M.D., M.P.H., a member of the USPSTF and co-author of the recommendation statements regarding calcium and vitamin D to prevent fractures and interventions to prevent falls in community-dwelling adults.

Interventions to Prevent Falls in Older AdultsUpdated Evidence Report and Systematic Review for the US Preventive Services Task Force

— JAMA editorial: Preventing Fractures and Falls

— JAMA Internal Medicine editorial: New Prevention Guidelines for Falls and Fractures

JAMA Patient Page: Vitamin D and Calcium Supplements for Preventing Fractures

For more details and to read the full report, please visit the For The Media website.


Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

Note: More information about the U.S. Preventive Services Task Force, its process, and its recommendations can be found on the newsroom page of its website.

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