JAMA Internal Medicine Study Highlights



JAMA Internal Medicine Study Highlights


Chia-Fang Wu, M.S., Ph.D., of Kaohsiung Medical University, Taiwan, and colleagues conducted a crossover study of noodle soup consumption in melamine bowls and total melamine excretion in urine. A continuous low-dose of melamine exposure may be associated with urolithiasis (urinary system stones) in children and adults, according to the study background.


According to a research letter reporting the study findings, 12 healthy individuals (six men and six women) participated in the investigation. One group consumed 500 mL of hot noodle soup in a melamine bowl and another group consumed soup in ceramic bowls. Urine samples were collected from all participants after consumption for 12 hours. After a three-week washout, the assigned treatments were reversed. Total melamine excretion in urine for 12 hours was 8.35 µg and 1.31 µg in melamine bowls and ceramic bowls, respectively, according to the study results.


“Melamine tableware may release large amounts of melamine when used to serve high-temperature foods. … The amount of melamine released into food and beverages from melamine tableware varies by brand, so the results of this study of one brand may not be generalized to other brands. … Although the clinical significance of what levels of urinary melamine concentration has not yet been established, the consequences of long-term melamine exposure still should be of concern,” the authors conclude.

(JAMA Intern Med. Published online January 14, 2013. doi:10.1001/jamainternmed.2013.1569; doi:10.1001/jamainternmed.2013.1597. Available pre-embargo to the media at http://media.jamanetwork.com.)


Editor’s Note: This study was supported by the Taiwan National Health Research Institutes, the National Science Council and Kaohsiung Medical University Hospital. Please see the articles for additional information, including other authors, author contributions and affiliations, financial disclosures, funding and support, etc.

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