Clinical Trial of Antibiotic Strategies for Uncomplicated Acute Appendicitis

JAMA

EMBARGOED FOR RELEASE: 11 A.M. (ET), MONDAY, JANUARY 11, 2021

Media advisory: The full study and editorial are linked to this news release. A visual abstract is below.

Embed this link to provide your readers free access to the full-text article This link will be live at the embargo time https://jamanetwork.com/journals/jama/fullarticle/10.1001/jama.2020.23525?guestAccessKey=5f6b0eb2-50eb-4a97-b06c-00b0630c9d51&utm_source=For_The_Media&utm_medium=referral&utm_campaign=ftm_links&utm_content=tfl&utm_term=011121

 

What The Study Did: This randomized clinical trial compares the effects of two antibiotic strategies (oral moxifloxacin versus intravenous ertapenem followed by oral levofloxacin) on hospital discharge without surgery and recurrent appendicitis over one year among adults presenting to the emergency department with uncomplicated acute appendicitis.

Authors: Paulina Salminen, M.D., Ph.D., of Turku University Hospital in Turku, Finland, is the corresponding author.

 

Visual Abstract

 

(doi:10.1001/jama.2020.23525)

Editor’s Note: The article includes conflicts of interest and funding/support disclosures. Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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