Association of Prenatal Exposure to Benzodiazepines With Development of Autism Spectrum, Attention-Deficit/Hyperactivity Disorders

JAMA Network Open


Media advisory: The full study is linked to this news release.

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About The Study: Researchers found in this study of 1.5 million children that after adjusting for possible confounders and accounting for possible parental genetic or familial factors, benzodiazepine exposure during pregnancy was not associated with increased risks of autism spectrum disorder or attention-deficit/hyperactivity disorder. These results challenge current assumptions of a potential association of neurodevelopmental disorders with maternal benzodiazepine use before or during pregnancy. 

Authors: Yi-Lung Chen, Ph.D., of Asia University in Taichung, Taiwan, and Mong-Liang Lu, M.D., M.S., of Taipei Medical University in Taipei, Taiwan, are the corresponding authors. 



Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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