Association of Allergy History With Allergy Symptoms After COVID-19 Vaccination

JAMA Network Open


Media advisory: The full study is linked to this news release.

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About JAMA Network Open: JAMA Network Open is the new online-only open access general medical journal from the JAMA Network. On weekdays, the journal publishes peer-reviewed clinical research and commentary in more than 40 medical and health subject areas. Every article is free online from the day of publication.


What The Study Did: In this study of nearly 53,000 health care employees, a self-reported history of high-risk allergy was associated with an increased risk of allergic reactions within three days of mRNA COVID-19 vaccination, but nearly all individuals, regardless of allergy history, were safely vaccinated.

Authors: Kimberly G. Blumenthal, M.D., M.Sc., of Massachusetts General Hospital in Boston, is the corresponding author.



Editor’s Note: Please see the article for additional information, including other authors, author contributions and affiliations, conflict of interest and financial disclosures, and funding and support.

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