Two Doses Of H-P-V Vaccine Associated With Reduction In The Risk Of Genital Warts

Video Script

Two Doses Of H-P-V Vaccine Associated With Reduction In The Risk Of Genital Warts

INTRO: Human Papillomavirus or H-P-V is one of the most common sexually transmitted infections.  The infection is important to prevent because it can cause cervical cancer and genital warts. A new study examined how many doses of the H-P-V vaccine are required to prevent genital warts, which usually develop before cervical cancer. Catherine Dolf has more in this week’s JAMA Report.

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Graphic:Pic of HPV traveling across screen, cervical cancer and condyloma or genital warts appears, syringes, one fills up slides across screen

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SOME STRAINS OF HUMAN PAPILLOMAVIRUS OR H-P-V CAN CAUSE CERVICAL CANCER AND CONDYLOMA ALSO KNOWN AS GENITAL WARTS. ONE H-P-V VACCINE IS RECOMMENDED TO BE GIVEN IN THREE DOSES TO PROTECT GIRLS AND YOUNG WOMEN AGAINST BOTH THESE ILLNESSES.

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SOT/FULL Super@:16 Lisen Arnheim-Dahlstr̦m, Ph.D., РKarolinska Institutet Runs:13
“We wanted to see whether two doses would offer equal protection or maybe better protection and which dose would be the most effective to use in protection against condyloma.”

(Video covering 2nd half of bite: Dr. Dr. Arnheim-Dahlström in lab)

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Dr. Arnheim-Dahlström in lab, shot of people walking on street, various shots of young women, girl getting vaccination

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DR. LISEN ARNHEIM-DAHLSTRÖM FROM THE KAROLINSKA INSTITUTET IN STOCKHOLM, SWEDEN AND CO-AUTHORS EXAMINED HEALTH CARE DATA OF MORE THAN A MILLION GIRLS AND YOUNG WOMEN ACROSS SWEDEN. THEY WERE BETWEEN THE AGES OF 10 AND 24. RESEARCHERS COMPARED THE OCCURRENCE OF GENITAL WARTS AMONG THOSE WHO RECEIVED 2 OR 3 DOSES OF THE VACCINE.

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SOT/FULL Super@:44 Lisen Arnheim-Dahlstr̦m, Ph.D., РKarolinska Institutet Runs:14
“The best protection would be after having three doses compared to having two doses. However, we also see that two doses, gives a substantial protection against condyloma.”

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JAMA COVER

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THE STUDY APPEARS IN JAMA, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

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SOT/FULL Super@ 1:02 Lisen Arnheim-Dahlstr̦m, Ph.D., РKarolinska Institutet Runs:17
“Even though we see in this study that three doses is optimal and two doses also gives a good protection that doesn’t mean we can translate that into what it means for the protection of cervical cancer.”

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Women working in lab with vials, machine sorting vials

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RESEARCHERS LOOKED AT GENITAL WARTS BECAUSE THEY USUALLY APPEAR 3 TO 6 MONTHS AFTER INFECTION. CERVICAL CANCER CAN TAKE UP TO A DECADE OR MORE TO DEVELOP.

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SOT/FULL Super@ 1:29 Lisen Arnheim-Dahlstr̦m, Ph.D., РKarolinska Institutet Runs:12
“If you could reduce from three doses to two doses that would help especially low income countries but also high income countries because the implementation of a vaccine program will probably run smoother.”

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Various shot of lab, girls in the community

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IT COULD BE LESS EXPENSIVE AND EASIER TO ADMINISTER USING JUST TWO DOSES. HOWEVER, PROTECTION WAS NOT QUITE AS HIGH AS WITH THE THREE DOSES.RESEARCHERS SAY FOR NOW GIRLS AND YOUNG WOMEN SHOULD CONTINUE THE RECOMMENDED THREE DOSE VACCINE SCHEDULE. CATHERINE DOLF THE JAMA REPORT.

TAG:RESEARCHERS SAY FURTHER STUDIES ARE NEEDED TO UNDERSTAND WHETHER THE NUMBER OF VACCINE DOSES WILL ALSO AFFECT THE RISK OF DEVELOPING CERVICAL CANCER.