Testosterone Therapy May Increase The Risk Of Heart Attack, Stroke And Other Cardiovascular Events

Video Script

Testosterone Therapy May Increase The Risk Of Heart Attack, Stroke And Other Cardiovascular Events

INTRO:Testosterone replacement therapy has been shown to improve muscle mass, bone density and sexual function. But what effect does this therapy have when it comes to heart attacks and stroke? A new study examined patients with low testosterone levels who received testosterone therapy. Catherine Dolf has more in this week’s JAMA Report.

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Men walking down hall, testosterone replacement medications, graphic:
Muscle Mass
Bone Strength
Sexual Function
Heart on computer screen

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AS MEN AGE THEIR TESTOSTERONE LEVELS OFTEN DECREASE. TESTOSTERONE THERAPY HAS BEEN SHOWN TO HELP IMPROVE MUSCLE MASS, BONE STRENGTH AND SEXUAL FUNCTION.  IT IS NOT CLEAR WHAT EFFECT IT MAY HAVE ON HEART ATTACKS AND STROKE.

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SOT/FULL Super@:12 P. Michael Ho, M.D., Ph.D., – VA Eastern Colorado Health Care System Runs:13
“The objective of this study was to look at the association between testosterone use and adverse cardiovascular outcomes including myocardial infarction, stroke and mortality.”

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Dr. Ho and colleagues talking, man signing in at hospital, VA hospital building, various shots of patient undergoing a coronary procedure

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DR. MICHAEL HO FROM THE VETERANS AFFAIRS EASTERN COLORADO HEALTH CARE SYSTEM AND CO-AUTHORS REVIEWED DATA FROM JUST OVER 8700 VETERANS WHO RECEIVED ROUTINE CLINICAL CARE AT SEVERAL V-A HOSPITALS AROUND THE COUNTRY. THEY ALL HAD LOW TESTOSTERONE LEVELS AND HAD UNDERGONE A CORONARY ANGIOGRAPHY, A TEST WHICH CAN DETECT BLOOD VESSEL BLOCKAGES IN THE HEART. 80 PERCENT WERE DIAGNOSED WITH HEART DISEASE THE OTHER 20 PERCENT WERE NOT.

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SOT/FULL Super@:50 P. Michael Ho, M.D., Ph.D., – VA Eastern Colorado Health Care System Runs:14
“Of these men who underwent coronary angiography and had low testosterone levels about 14 percent of patients were started on testosterone therapy at some point in time after the procedure.”

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Vial of testosterone medication, testosterone patch

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THE TESTOSTERONE THERAPY WAS DELIVERED BY INJECTION OR A PATCH.

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SOT/FULL Super@1:08 P. Michael Ho, M.D., Ph.D., – VA Eastern Colorado Health Care System Runs:12
“Men who are started on testosterone therapy had a higher risk of death, heart attack and stroke compared to men who were not started on testosterone therapy after their coronary angiogram.”

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JAMA COVER

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Dr. Ho sitting at desk on the phone, looking at computer

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THE STUDY APPEARS IN JAMA, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.THE AUTHORS SAY THIS STUDY CAN HELP PHYSICIANS DISCUSS TESTOSTERONE REPLACEMENT WITH THEIR PATIENTS.

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SOT/FULL Super@1:30 P. Michael Ho, M.D., Ph.D., – VA Eastern Colorado Health Care System Runs:18
“This should enter into the discussion between physicians and patients about whether patients should go on testosterone replacement therapy and will hopefully help that discussion in terms of what the benefits are and what the potential risks are.”

(Video covering 2nd half of bite: different shots of testosterone medications)

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Testosterone medication labels

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CATHERINE DOLF THE JAMA REPORT.

TAG:RESEARCHERS SUGGEST ADDITIONAL STUDIES TO TRY AND BETTER UNDERSTAND OTHER POTENTIAL RISKS ASSOCIATED WITH TESTOSTERONE THERAPY.