Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Archives of Internal Medicine Study Highlights A national survey of 7,288 physicians (26.7 percent participation rate) finds that 45.8 percent of physicians reported at least one symptom of burnout (Online First, see news release below). A study that examined the association of delirium and cognitive…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 21, 2012 Preventing Patient Harms Through Systems of Care Peter J. Pronovost, M.D., Ph.D., of the Johns Hopkins Medical Institutions, Baltimore, and George W. Bo-Linn, M.D., M.H.A., of the Gordon and Betty Moore Foundation, Palo Alto, Calif., discuss the problem of preventable harms to patients, which include…

Addition of Carotid Artery Wall Thickness to Risk Model Associated With Small Improvement in Prediction of Heart Attack, Stroke

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 21, 2012 Media Advisory: To contact co-author Michiel L. Bots, M.D., Ph.D., email m.l.bots@umcutrecht.nl. CHICAGO – In an analysis of data from previously published studies that included more than 45,000 patients, the value of adding to the Framingham Risk Score a measure of the common carotid artery…

Statin Therapy Associated With Lower Risk of Pancreatitis

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 21, 2012 Media Advisory: To contact David Preiss, M.D., Ph.D., email david.preiss@glasgow.ac.uk. CHICAGO – Although some studies have suggested that use of lipid-lowering therapies may increase the risk of pancreatitis, an analysis that involved pooling of data from previous studies and included more than 150,000 participants found…

Use of Newer-Generation Drug-Releasing Stent Results in Lower Rate of Adverse Cardiac Events For Heart Attack Patients

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 21, 2012 Media Advisory: To contact corresponding author Stephan Windecker, M.D., email stephan.windecker@insel.ch. To contact editorial co-author Adnan Kastrati, M.D., email kastrati@dhm.mhn.de. CHICAGO – Compared with a bare-metal stent, the use of a stent with a biodegradable polymer that releases the drug biolimus resulted in a lower…

Measure of Coronary Artery Calcium Associated With Improved Prediction of Cardiovascular Disease Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 21, 2012 Media Advisory: To contact Joseph Yeboah, M.D., M.S., call Marguerite Beck at 336-716-2415 or email marbeck@wakehealth.edu. To contact editorial co-author J. Michael Gaziano, M.D., M.P.H., call Lori Schroth at 617-534-1604 or email ljschroth@partners.org. CHICAGO – In a comparison of novel cardiovascular risk markers, coronary artery…

Studies Examine Health Consequences of Meltdown, Damage to Fukushima Nuclear Power Plants in Japan

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 14, 2012 Media Advisory: To contact the corresponding author for the first study, Takeshi Tanigawa, M.D., Ph.D., email tt9178tt9178@gmail.com. To contact the corresponding author for the second study, Masaharu Tsubokura, M.D., email tsubokura-tky@umin.ac.jp. CHICAGO – The results of two studies in the August 15 issue of JAMA…

Viewpoints in This Week’s JAMA Theme Issue on Violence and Human Rights

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 14, 2012 Preventing Suicides in U.S. Service Members and Veterans – Concerns After a Decade of War Charles W. Hoge, M.D., of the Walter Reed Army Institute of Research, Silver Spring, Md., and Carl A. Castro, Ph.D., of the U.S. Army Medical Research and Materiel Command, Fort…

For Individuals With PTSD and Substance Dependence, Integrated Treatment Program Provides Greater PTSD Symptom Relief

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 14, 2012 Media Advisory: To contact Katherine L. Mills, Ph.D., email k.mills@unsw.edu.au. CHICAGO – Study participants who received an integrated treatment for posttraumatic stress disorder (PTSD) and substance dependence plus usual treatment for substance dependence showed significantly greater reductions in PTSD symptom severity compared with participants who…

Computer-Based Screening Program For Partner Violence Does Not Result in Significant Improvement in Quality of Life, Reduction in Partner Violence

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 14, 2012 Media Advisory: To contact Joanne Klevens, M.D., Ph.D., call Gail Hayes at 770-488-4902 or email shayes@cdc.gov. To contact editorial co-author C. Nadine Wathen, Ph.D., call Jeff Renaud at 519-661-2111, ext. 85165, or email jrenaud9@uwo.ca. CHICAGO – In a study that included more than 2,700 women receiving…

Couple’s Therapy Appears to Decrease PTSD Symptoms, Improve Relationship

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 14, 2012 Media Advisory: To contact Candice M. Monson, Ph.D., call Suelan Toye at 416-979-5000, ext. 7161 or email stoye@ryerson.ca. To contact editorial author Lisa M. Najavits, Ph.D., call Gina DiGravio at 617-638-8480 or email gina.digravio@bmc.org. CHICAGO – Among couples in which one partner was diagnosed as…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 13, 2012 Archives of Neurology Study Highlights A phase 2 randomized study to determine the safety and tolerability of a medication called avagacestat (an oral γ-secretase inhibitor) for patients with Alzheimer disease found that in 209 patients with mild to moderate disease, the drug was well tolerated…

Archives of Ophthalmology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 13, 2012 Archives of Ophthalmology Study Highlights A study of 6,966 Medicare beneficiaries between 2004 and 2006 found that there does not appear to be a statistically significant association between vitamin D deficiency and subsequent diagnosis of either nonneovascular (dry) or neovascular (wet) age-related macular degeneration, according…

Strategy Appears to Help Rule-In, Rule-Out Heart Attack Within 1 Hour

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 13, 2012 Media Advisory: To contact corresponding author Christian Mueller, M.D., F.E.S.C., email chmueller@uhbs.ch. To contact commentary L. Kristin Newby, M.D., M.H.S., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – A strategy using an algorithm that incorporates high-sensitivity cardiac troponin T (hs-cTnT) values appears to be…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 13, 2012 Archives of Internal Medicine Study Highlights A strategy using an algorithm that incorporates high-sensitivity cardiac troponin T (hs-cTnT) values appears to be associated with ruling-out or ruling-in myocardial infarction (heart attack) within one hour in 77 percent of patients with acute chest pain who presented…

Pay for Performance Appears Associated with Improved Treatment Implementation for Adolescent Substance Use Disorders

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 13, 2012 Media Advisory: To contact Bryan R. Garner, Ph.D., call Celeste Brennan at 309-820-3717 or email cbrennan@chestnut.org. To reach editorial author Alyna T. Chien, M.D., M.S., call Erin Tornatore at 617-919-3110 or email erin.tornatore@childrens.harvard.edu. CHICAGO– Pay for performance appears to be associated with improved implementation of…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 7, 2012 Transcatheter Valve Replacement for Aortic Stenosis – Balancing Benefits, Risks, and Expectations Chintan S. Desai, M.D., and Robert O. Bonow, M.D., of the Northwestern University Feinberg School of Medicine, Chicago, write that “transcatheter aortic valve replacement (TAVR) represents a transformative technology with potential for the…

Adults Who Are Normal Weight At Time of Diabetes Diagnosis Have Higher Rate of Death Than Those Who Are Overweight At Diagnosis

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 7, 2012 Media Advisory: To contact Mercedes R. Carnethon, Ph.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. To contact Hermes Florez, M.D., M.P.H., Ph.D., call Lisa Worley at 305-243-5184 or email lworley2@med.miami.edu. CHICAGO – Participants in a study who were normal weight at the time of…

Cholesterol Levels Appear To Be Improving Among U.S. Youths

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, AUGUST 7, 2012 Media Advisory: To contact Brian K. Kit, M.D., M.P.H., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. To contact editorial author Sarah D. de Ferranti, M.D., M.P.H., call Rob Graham at 617-919-3110 or email rob.graham@childrens.harvard.edu. CHICAGO – In a study involving more than 16,000 U.S….

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights The odds of undergoing cranial computed tomography (CT) among children with minor blunt head trauma who were at higher risk for clinically important traumatic brain injury did not appear to differ by race/ethnicity in a secondary analysis…

Study Examines Racial/Ethnic Disparities in Cranial CT Among Children

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Media Advisory: To contact JoAnne E. Natale, M.D., Ph.D., call Phyllis Brown at 916-734-9023 or email phyllis.brown@ucdmc.ucdavis.edu. To reach editorial author M. Denise Dowd, M.D., M.P.H., call Melissa Novak at 816-346-1341 or email mdnovak@cmh.edu. CHICAGO – The odds of undergoing cranial computed tomography (CT) among…

Study Examines Decision-Making Brain Activity in Patients with Hoarding Disorder

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Media Advisory: To contact David F. Tolin, Ph.D., call Rebecca Stewart at 860-545-4285 or email rstewart@harthosp.org.  CHICAGO– Patients with hoarding disorder exhibited abnormal activity in regions of the brain that was stimulus dependent when deciding what to do with objects that did or did not…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Archives of General Psychiatry Study Highlights Patients with hoarding disorder (defined as the excessive collection of objects and an inability to discard them) exhibited abnormal activity in regions of the brain that was stimulus dependent when deciding what to do with objects that did or…

Study Examines Effects of Growth Hormone-Releasing Hormone on Cognitive Function

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Media Advisory: To contact Laura D. Baker, Ph.D., call Leila Gray at 206-685-0381 or email leilag@uw.edu. CHICAGO– Treatment with growth hormone-releasing hormone appears to be associated with favorable cognitive effects among both adults with mild cognitive impairment and healthy older adults, according to a randomized…

Physical Activity Associated with Lower Risk of Death in Patients with Diabetes

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Media Advisory: To contact Diewertje Sluik, M.Sc., email Diewertje.Sluik@dife.de. To contact editorial author Mitchell H. Katz, M.D., call Michael Wilson at 213-240-8059 or e-mail micwilson@dhs.lacounty.gov. CHICAGO– Higher levels of physical activity were related to lower risk of death in patients with diabetes, according to a report published…

Weight Training Associated with Lower Risk of Type 2 Diabetes in Study of Men

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Media Advisory: To contact corresponding author Frank B. Hu, M.D., Ph.D., call Marge Dwyer at 617-432-8416 or email mhdwyer@hsph.harvard.edu. CHICAGO – Weight training was linked with a reduced risk of type 2 diabetes in a study of male health professionals, and those men who engaged…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 6, 2012 Archives of Internal Medicine Study Highlights Weight training was linked with a reduced risk of type 2 diabetes in a study of male health professionals, and those men who engaged in weight training and aerobic exercise for at least 150 minutes a week had the…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 31, 2012 Study Evaluates Association of Pertussis Vaccine Type and Administration With Reports of Pertussis Cases Similar to North America, Australia is experiencing a sustained pertussis epidemic, with the highest incidence rates in Queensland during 2011 in children age 6 to 11 years. The recent changes in…

Endoscopic Procedure For Acquiring Veins For Coronary Artery Bypass Graft Surgery Not Associated With Increased Risk of Death

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 31, 2012 Media Advisory: To contact corresponding author Peter K. Smith, M.D., call Debbe Geiger at 919-660-9461 or email debbe.geiger@dm.duke.edu. To contact editorial author Lawrence J. Dacey, M.D., M.S., call David Corriveau at 603-653-1978 or email David.A.Corriveau@hitchcock.org. CHICAGO – Although there have been questions regarding the safety…

Study Finds Correlation Between Number of Colorectal Polyps and Genetic Mutations

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 31, 2012 Media Advisory: To contact corresponding author Sapna Syngal, M.D., M.P.H., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. To contact editorial co-author Hemant K. Roy, M.D., call Jim Anthony at 847-570-6132 or email janthony@northshore.org. CHICAGO – Among patients with multiple colorectal polyps, the prevalence of…

Exercise Results in Modest Reduction in Symptoms of Depression for Patients With Chronic Heart Failure

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 31, 2012 Media Advisory: To contact James A. Blumenthal, Ph.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Patients with chronic heart failure who participated in exercise training had modest reductions in symptoms of depression after 12 months, compared with usual care, according to a…

Older Patients Have Lower Risk of Hip Fracture After Cataract Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 31, 2012 Media Advisory: To contact corresponding author Anne L. Coleman, M.D., Ph.D., call Elaine Schmidt at 310-794-2272 or email eschmidt@mednet.ucla.edu. CHICAGO – Medicare patients 65 years and older who underwent cataract surgery had a lower odds of hip fracture 1 year after the procedure when compared…

Study Examines Use of Diagnostic Tests in Adolescents with Hypertension

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 23, 2012 Media Advisory: To contact Esther Y. Yoon, M.D., M.P.H., call Mary Masson at 734-764-2220 or email mfmasson@med.umich.edu. To reach editorial author Sarah D. de Ferranti, M.D., M.P.H., call Keri Stedman at 617-919-3110 or email keri.stedman@childrens.harvard.edu. CHICAGO– A study of adolescents with hypertension enrolled in the Michigan…

Increased Heart Attack Risk Associated with Total Hip, Knee Replacement Surgeries

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 23, 2012 Media Advisory: To contact author Arief Lalmohamed, Pharm.D., email a.lalmohamed@uu.nl. To contact commentary author Arthur W. Wallace, M.D., Ph.D., call Kristen Bole at 415-476-2743 or email kristen.bole@ucsf.edu. CHICAGO – Total hip replacement (THR) and total knee replacement (TKR) surgeries were associated with increased risk of…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 23, 2012 Archives of Neurology Study Highlights Shortening of chromosomal telomeres, which provide a protective role for genetic material, is a consequence of cell division. The findings of a study of 1,983 people (average age 78.3 years) enrolled in a population-based study of aging and dementia in…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 23, 2012 Archives of Internal Medicine Study Highlights Total hip replacement and total knee replacement were associated with increased risk of acute myocardial infarction (AMI, heart attack) in the first two weeks after the surgical procedures (Online First, see news release below). A study that describes intensive…

Also Appearing in This JAMA HIV/AIDS Theme Issue

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) SUNDAY, JULY 22, 2012 Use of Hydroxychloroquine Does Not Slow HIV Disease Progression Among Patients Not Taking Antiretroviral Therapy Nicholas I. Paton, M.D., F.R.C.P., of the MRC Clinical Trials Unit, London, and colleagues conducted a study to examine whether hydroxychloroquine decreases immune activation and inflammation and subsequently slows…

Working Toward an AIDS-Free Generation

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) SUNDAY, JULY 22, 2012 Media Advisory: To contact Anthony S. Fauci, M.D., call Kathy Stover at 301-402-1663 or email Kathy.stover@nih.gov. WASHINGTON, D.C. – Ending the global HIV/AIDS pandemic may be possible by implementing a multifaceted global effort that expands testing, treatment, and prevention programs, as well as meets…

Study Finds Differences in Characteristics, Risk Factors Between Persons Born Outside the United States vs. U.S.-Born Residents With HIV

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) SUNDAY, JULY 22, 2012 Media Advisory: To contact H. Irene Hall, Ph.D., call the National Center for HIV/AIDS, Viral Hepatitis, STD and TB Prevention press office at 404-639-8895 or email NCHHSTPMediaTeam@cdc.gov. WASHINGTON, D.C. – An examination of the characteristics of persons born outside the United States diagnosed with…

HIV-Infected Women Do Not Appear To Be At Increased Risk of Cervical Cancer

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) SUNDAY, JULY 22, 2012 Media Advisory: To contact Howard D. Strickler, M.D., M.P.H., call Deirdre Branley at 347-266-9204 or email sciencenews@einstein.yu.edu. WASHINGTON, D.C. – HIV-infected and uninfected women with normal cervical cytology (Pap test) and a negative test result for oncogenic (tumor inducing) human papillomavirus DNA at study…

Among New HIV Treatment Recommendations, All Adult HIV Patients Should Be Offered Antiretroviral Therapy, Regardless of CD4 Cell Count

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) SUNDAY, JULY 22, 2012 Media Advisory: To contact Melanie A. Thompson, M.D., email drmt@mindspring.com, or contact Donna Jacobsen, Executive Director of IAS-USA at DJacobsen@iasusa.org or 415-544-9400. WASHINGTON, D.C. – Included in the 2012 International Antiviral Society-USA panel recommendations for human immunodeficiency virus (HIV) patient care is that all adult patients, regardless of…

Study Examines Patient Experience at Safety-Net Hospitals

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Media Advisory: To contact corresponding author Ashish K. Jha, M.D., M.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu. To contact editorial author Mitchell H. Katz, M.D., call Michael Wilson at 213-240-8059 or e-mail micwilson@dhs.lacounty.gov. CHICAGO – A study suggests that safety-net hospitals (SNHs), which…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Internal Medicine Study Highlights A study suggests that safety-net hospitals (SNHs), which typically care for poor patients, performed more poorly than other hospitals on nearly every measure of patient experience, a situation that could have financial consequences as hospital payments are connected to…

Study Examines Health Care Expenditures After Bariatric Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Media Advisory: To contact Matthew L. Maciejewski, Ph.D., call Peter Tillman 919-824-3769 or email peter.tillman@va.gov. CHICAGO– A study suggests bariatric surgery to treat obesity was not associated with reduced health care expenditures three years after the procedure in a group of predominantly older men, according…

Archives of Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Surgery Study Highlights Bariatric surgery to treat obesity was not associated with reduced health care expenditures three years after the procedure in a study of predominantly older men (see news release below). Results of a study of 303 patients with mild gallstone pancreatitis…

Study Suggests Racial Disparities May Exist in Larynx Preservation Therapy for Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Media Advisory: To contact corresponding author Allen M. Chen, M.D., call Dorsey Griffith at 916-734-9118 or email dorsey.griffith@ucdmc.ucdavis.edu. CHICAGO– A study of laryngeal (voice box) cancers suggests that racial disparities may exist with black patients less likely to undergo larynx preservation than white patients, according…

Archives of Otolaryngology–Head & Neck Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Otolaryngology–Head & Neck Surgery Study Highlights A study of laryngeal (voice box) cancers suggests that racial disparities may exist, with black patients less likely to undergo larynx preservation than white patients (see news release below). Balloon dilation may be beneficial for children with…

Study Finds Increases in Restrictions on Indoor Tanning in Several Countries

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Media Advisory: To contact corresponding author Robert P. Dellavalle, M.D., Ph.D., M.S.P.H., call Lyndsey Crum at 303-941-7400 or email lyndsey.crum@ucdenver.edu. To contact corresponding commentary author Steven Q. Wang, M.D., call Courtney Nowak at 212-639-3573 or email denicolc@mskcc.org. CHICAGO– Restrictions on indoor tanning, which studies suggest…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Dermatology Study Highlights Restrictions on indoor tanning, which studies suggest is linked to skin cancer, have increased in several countries since 2003 (Online First, see news release below). According to a research letter, a study of nearly 400 female students at two Midwestern…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Neurology Study Highlights A study describes a panel of plasma biomarkers that researchers suggest may distinguish patients with Alzheimer disease (AD), a progressive neurodegenerative disease, from cognitively healthy individuals. Researchers comment that the biomarkers identified in the analysis of data from the Australian…

Archives of Facial Plastic Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 16, 2012 Archives of Facial Plastic Surgery Study Highlights A study of 263 patients who underwent face and neck lift procedures suggests that antidepressant medication use by patients was not associated with an increased risk of bleeding. The study notes selective serotonin reuptake inhibitors (SSRIs) have come…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 17, 2012 Is It Time to Replace the Tuberculin Skin Test With a Blood Test? “Recent mathematical tuberculosis (TB) transmission modeling has shown that substantial improvements in addressing latent tuberculosis infection (LTBI) will be needed to eliminate TB before the 22nd century,” writes Philip A. LoBue, M.D.,…

Study Examines Variation, Factors Involved With Patient-Sharing Networks Among Physicians in U.S.

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 17, 2012 Media Advisory: To contact Bruce E. Landon, M.D., M.B.A., call David Cameron at 617-432-0441 or email david_cameron@hms.harvard.edu. To contact editorial co-author Elliott S. Fisher, M.D., M.P.H., call Annmarie Christensen at 603-653-0897 or email Annmarie.Christensen@dartmouth.edu. CHICAGO – Physicians tend to share patients with colleagues who have…

Treating Chronic Hepatitis C With Milk Thistle Extract Does Not Appear Beneficial

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 17, 2012 Media Advisory: To contact Michael W. Fried, M.D., call Tom Hughes at 919-966-6047 or email tahughes@unch.unc.edu. CHICAGO – Use of the botanical product silymarin, an extract of milk thistle that is commonly used by some patients with chronic liver disease, did not provide greater benefit…

Including Stroke Severity in Risk Models Associated With Improved Prediction of Risk of Death

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 17, 2012 Media Advisory: To contact Gregg C. Fonarow, M.D., call Rachel Champeau at 310-794-2270 or email RChampeau@mednet.ucla.edu. To contact editorial co-author Tobias Kurth, M.D., Sc.D., email tobias.kurth@univ-bordeaux.fr. CHICAGO – Adding stroke severity to a hospital 30-day mortality model based on claims data for Medicare beneficiaries with…

Treatment of Multiple Sclerosis With Interferon Beta Is Not Associated With Less Progression of Disability

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 17, 2012 Media Advisory: To contact corresponding author Helen Tremlett, Ph.D., call Brian Lin at 604-822-6397 or email brian.lin@ubc.ca. To contact editorial co-author Ludwig Kappos, M.D., email lkappos@uhbs.ch   CHICAGO – Among patients with relapsing-remitting multiple sclerosis (MS), treatment with the widely-prescribed drug to treat MS, interferon…

Use of Drug-Eluting Stents Varies Widely; Only Modestly Correlated with Risk of Coronary Artery Restenosis

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Media Advisory: To contact corresponding author Robert W. Yeh, M.D., M.Sc., call Ryan Donovan at 617-724-6433 or email rcdonovan@partners.org. To contact commentary author Peter W. Groeneveld, M.D., M.S., call Katie Delach at 215-349-5964 or email katie.delach@uphs.upenn.edu. CHICAGO – A study based on more than 1.5…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 10, 2012 The Moral Duty to Buy Health Insurance Tina Rulli, Ph.D., of the NIH Clinical Center, Bethesda, Md., and colleagues write that one of the most controversial features of the 2010 Patient Protection and Affordable Care Act (ACA) is the requirement that U.S. residents purchase health…

Study Examines Quality of Life Factors at End of Life for Patients with Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Media Advisory: To contact corresponding author Holly G. Prigerson, Ph.D., call Anne Doerr at 617-632-4090 or email anne_doerr@dfci.harvard.edu. To contact corresponding commentary author Alan B. Zonderman Ph.D., call Megan Homer at 301-496-1752 or email nianews3@mail.nih.gov. CHICAGO – Better quality of life at the end of…

Receiving Chemotherapy Following Surgical Removal of Type of Cancer Near Pancreas May Improve Survival

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 10, 2012 Media Advisory: To contact John P. Neoptolemos, M.D., email J.P.Neoptolemos@liverpool.ac.uk. CHICAGO – Patients who had surgery for periampullary cancer (a variety of types of cancer that are located in and near the head of the pancreas, including an area called the ampulla where the bile…

H1N1 Vaccine Associated With Small but Significant Risk of Guillain-Barre Syndrome

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 10, 2012 Media Advisory: To contact Philippe De Wals, M.D., Ph.D., call Sylvain Gagné at 418-656-3952 or email sylvain.gagne@dc.ulaval.ca. Guillain-Barre syndrome (GBS) is usually characterized by rapidly developing motor weakness and areflexia (the absence of reflexes). “The disease is thought to be autoimmune and triggered by a…

Cranberry Products Associated with Prevention of Urinary Tract Infections

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Media Advisory: To contact corresponding author Chien-Chang Lee, M.D., M.Sc., email cclee100@gmail.com. CHICAGO– Use of cranberry-containing products appears to be associated with prevention of urinary tract infections in some individuals, according to a study that reviewed the available medical literature and was published by Archives…

Administration of Regulating Agent Prior to Coronary Artery Bypass Graft Surgery Does Not Appear to Improve Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 10, 2012 Media Advisory: To contact Mark F. Newman, M.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Among intermediate- to high-risk patients undergoing coronary artery bypass graft surgery, administration of the agent acadesine to regulate adenosine (a naturally occurring chemical that dilates blood flow…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Archives of Internal Medicine Study Highlights A study that reviewed the available medical literature suggests that use of cranberry-containing products appears to be associated with prevention of urinary tract infections in some individuals (see news release below). Better quality of life at the end of…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Archives of Neurology Study Highlights A study of patients with stroke admitted to English National Health Service public hospitals suggests that patients who were hospitalized on weekends were less likely to receive urgent treatments and had worse outcomes (Online First, see news release below). A…

Study Suggests Poorer Outcomes for Patients with Stroke Hospitalized on Weekends

  EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Media Advisory: To contact William L. Palmer, M.A., M.Sc., email w.palmer07@imperial.ac.uk. CHICAGO– A study of patients with stroke admitted to English National Health Service public hospitals suggests that patients who were hospitalized on weekends were less likely to receive urgent treatments and had worse outcomes,…

Archives of Ophthalmology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 9, 2012 Archives of Ophthalmology Study Highlights A study suggests that glaucoma, ocular hypertension, or both, occurs more often in the eyes of patients with severe Fuchs endothelial corneal dystrophy (FECD), a condition associated with progressive endothelial dysfunction and corneal edema that can result in vision loss…

Studies Examine Risk of Poor Birth Outcomes, Nervous System Disorder Following H1N1 Vaccination

  EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 10, 2012 Media Advisory: To contact co-author Anders Hviid, M.Sc., Dr.Med.Sci., email aii@ssi.dk or call +45-32683967. To contact editorial co-author Mark C. Steinhoff, M.D., call Jim Feuer at 513-636-4656 or email jim.feuer@cchmc.org. CHICAGO – In studies examining the risk of adverse outcomes after receipt of the…

Receipt of Shingles Vaccine Among Patients With Diseases Like Psoriasis and Rheumatoid Arthritis Not Associated With Increased Risk of Shingles

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 3, 2012 Media Advisory: To contact corresponding author Jeffrey R. Curtis, M.D., M.S., M.P.H., call Bob Shepard at 205-934-8934 or email Bshep@uab.edu. CHICAGO – Although some have suggested that patients receiving medication for immune-mediated diseases such as rheumatoid arthritis or psoriasis may be at increased risk of…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 3, 2012 Projected Explosive Material, Not Blast Pressure, May Be Primary Cause of Eye Injuries From Fireworks “Injuries from fireworks are prevalent among youth. The eye is the most frequently injured body part and accounts for more than 2,000 injuries annually. Although it is suggested that the…

Rate of Community-Onset MRSA Infections Appears To Be On the Decline

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JULY 3, 2012 Media Advisory: To contact corresponding author Clinton K. Murray, M.D., call Jen Rodriguez at 210-916-5141 or email jen.d.rodriguez@us.army.mil. CHICAGO – In analysis that included more than 9 million Department of Defense nonactive and active duty personnel, the rates of both community-onset and hospital-onset methicillin-resistant Staphylococcus…

New Names for 9 JAMA Network Archives Journals Starting January 1, 2013

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email mediarelations@jamanetwork.org. CHICAGO –  The nine specialty Archives Journals in the JAMA Network will change their names effective Jan. 1, 2013, part of the ongoing evolution to more closely interconnect the…

New Names for 9 JAMA Network Archives Journals Starting January 1, 2013

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: For more information, contact JAMA Network Media Relations at 312-464-JAMA (5262) or email mediarelations@jamanetwork.org. CHICAGO–  The nine specialty Archives Journals in the JAMA Network will change their names effective Jan. 1, 2013, part of the ongoing evolution to more closely interconnect the scientific…

Study Examines Fingolimod Therapy in Patients with Multiple Sclerosis

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact Ernst-Wilhelm Radue, M.D., email eradue@uhbs.ch. CHICAGO– The medication fingolimod reduced inflammatory lesion activity and reduced brain volume loss in patients with multiple sclerosis who participated in a two-year placebo-controlled clinical trial and were assessed by magnetic resonance imaging (MRI) measures, according…

Study Examines Outcomes of Patients Who Refuse Transfusion Following Cardiac Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact corresponding author Colleen G. Koch, M.D., M.S., M.B.A., call Wyatt DuBois at 216-445-9946 or email duboisw@ccf.org. To contact commentary author Victor A. Ferraris, M.D., Ph.D., call Allison Perry at 859-323-2399 or email allison.perry@uky.edu. CHICAGO– Jehovah’s Witness patients who undergo cardiac surgery…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Archives of Internal Medicine Study Highlights Jehovah’s Witness patients who undergo cardiac surgery do not appear to be at increased risk for surgical complications or death when compared to patients who undergo cardiac surgery and receive blood transfusions (Online First; see news release below). According…

Medicare Coverage Gap Associated with Reductions in Antidepressant Use in Study

  EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact Yuting Zhang, Ph.D., call Allison Hydzik and Cyndy McGrath at 412-647-9975 or email hydzikam@upmc.edu and mcgrathc3@upmc.edu. CHICAGO– The Medicare Part D coverage gap was associated with reduced use of antidepressants in a study of beneficiaries 65 years or older with depression,…

Study Suggests Antipsychotic Drugs During Pregnancy Linked to Increased Risk of Gestational Diabetes

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact author Robert Bodén. M.D., Ph.D., email robert.boden@neuro.uu.se. CHICAGO– A study that examined maternal use of antipsychotic drugs during pregnancy suggests that these medications may be linked to an increased risk of gestational diabetes, according to a report in the July issue…

Common Factors Suggested in Study of Autism Spectrum Disorders, Schizophrenia, Bipolar Disorder

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact Patrick F. Sullivan M.D., F.R.A.N.Z.C.P., call Karen Moon at 919-962-8595 or email karen_moon@unc.edu. CHICAGO – Schizophrenia or bipolar disorder in first-degree relatives, such as parents or siblings, may be associated with increased risk of autism spectrum disorder (ASD), according to a…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Archives of General Psychiatry Study Highlights A study that examined the maternal use of antipsychotic drugs during pregnancy suggests that these medications may be linked to an increased risk of gestational diabetes (see news release below). Schizophrenia or bipolar disorder in first-degree relatives, such as…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A study of students at seven public high schools in Texas suggests that “sexting” (a combination of the words sex and texting, which is the practice of electronically sending sexually explicit images or messages) was prevalent and…

Study Suggests Teen Sexting Prevalent, May Be Linked to Sexual Behaviors

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JULY 2, 2012 Media Advisory: To contact Jeff. R. Temple, Ph.D., call Brianne O’Donnell at 212-220-4444 or email brianne.odonnell@gabbe.com. To reach editorial author Megan A. Moreno, M.D., M.S.Ed., M.P.H., call Toni Morrissey (608) 263-3223 or email tmorrissey@uwhealth.org. CHICAGO– A study of students at seven public high schools in…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 26, 2012   Bone Density Screening Intervals for Osteoporosis – One Size Does Not Fit All Elaine W. Yu, M.D., and Joel S. Finkelstein, M.D., of Massachusetts General Hospital, Boston, write that Medicare data indicate that over a 7-year period, only 52 percent of eligible women had…

Study Examines Outcomes For Patients Receiving Warfarin Prior to Stroke and Treated With Anti-Clotting Agent

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 26, 2012 Media Advisory: To contact corresponding author Eric D. Peterson, M.D., M.P.H., call Debbe Geiger at 919-660-9461 or email Debbe.Geiger@duke.edu. To contact editorial author Mark J. Alberts, M.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO – The use of intravenous tissue plasminogen activator (tPA)…

Use of Limited Radiation Therapy Not Associated With Worse Outcomes for Children Responsive to Chemotherapy for Favorable-Risk Hodgkin Lymphoma

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 26, 2012 Media Advisory: To contact Monika L. Metzger, M.D., call Summer Freeman at 901-595-3061 or email summer.freeman@stjude.org. To contact editorial co-author Frederick D. Goldman, M.D., call Clinton Colmenares at 205-934-3887 or email ccolmena@uab.edu. CHICAGO – Among children with favorable-risk Hodgkin lymphoma and a complete early response…

Stepped-Care Intervention Results in Weight Loss, at Lower Cost

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 26, 2012 Media Advisory: To contact John M. Jakicic, Ph.D., call Patricia Lomando White at 412-624-9101 or email laer@pitt.edu. To contact editorial author George A. Bray, M.D., call Angela deGravelles at 225-202-5073 or email robin.post@pbrc.edu. CHICAGO – Although a standard behavioral weight loss intervention among overweight and…

Study Compares Effect of Three Common Diets on Energy Expenditure Following Weight Loss

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 26, 2012 Media Advisory: To contact corresponding author David S. Ludwig, M.D., Ph.D., call Keri Stedman at 617-919-3114 or email keri.stedman@childrens.harvard.edu. CHICAGO – In an examination of the effect on energy expenditure and components of the metabolic syndrome of 3 types of commonly consumed diets following weight…

Federal Government Spends Substantial and Increasing Amount on Duplicate Payments to Separate Managed Care Programs For Care of Same Individuals

EMBARGOED FOR EARLY RELEASE: 7 A.M. (CT) TUESDAY, JUNE 26, 2012 Media Advisory: To contact Amal N. Trivedi, M.D., M.P.H., call David Orenstein at 401-863-1862 or email david_orenstein@brown.edu. CHICAGO – An analysis that included 1.2 million veterans enrolled in the Veterans Affairs health care system and Medicare Advantage plan finds that the federal government spends…

Higher Medical Home Performance Rating of Community Health Centers Associated With Higher Operating Costs

EMBARGOED FOR EARLY RELEASE: 3:30 P.M. (CT) SUNDAY, JUNE 24, 2012 Media Advisory: To contact Robert S. Nocon, M.H.S., call Rob Mitchum at 773-484-9890 or email Robert.Mitchum@uchospitals.edu. To contact editorial co-author Robert J. Reid, M.D., Ph.D., call Joan DeClaire at 206-947-4560 or email declaire.j@ghc.org. CHICAGO – Federally funded community health centers with higher patient-centered medical…

Statins Appear Associated with Reduced Risk of Recurrent Cardiovascular Events in Men, Women

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 25, 2012 Media Advisory: To contact Jose Gutierrez, M.D., M.P.H., call Karin Eskenazi at 212-342-0508 or email ket2116@columbia.edu. To contact corresponding invited commentary author Fiona Taylor, Ph.D., HonMFPH, email Fiona.Taylor@lshtm.ac.uk. CHICAGO– Cholesterol-lowering statin drugs appear to be associated with reduced risk of recurrent cardiovascular events in men…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 25, 2012 Archives of Internal Medicine Study Highlights Cholesterol-lowering statin drugs appear to be associated with reduced risk for recurrent cardiovascular events in men and women, but do not appear to be associated with reduced all-cause mortality or stroke in women (see news release below). According to…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012  Archives of Dermatology Study Highlights A population-based study from theUnited Kingdomsuggests that the common skin condition psoriasis may be a risk factor for the development of Type 2 diabetes mellitus (Online First, see news release below). Smoking appears to be associated with an increased risk…

Study Suggests Laparoscopic Gastric Bypass Surgery Appears to be Safer Than Open Procedure

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Media Advisory: To contact corresponding John M. Morton, M.D., M.P.H., call John Sanford at 650-723-8309 or email jsanford@stanfordmed.org. CHICAGO–  A study that examined national outcome differences between laparoscopic Roux-en-Y gastric bypass and open Roux-en-Y gastric bypass suggests that the minimally invasive laparoscopic procedure was associated…

Survey Finds Surgical Interns Concerned about Training Duty-Hour Restrictions

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Media Advisory: To contact corresponding author David R. Farley, M.D., call Brian Kilen at 507-284-5005 or email Kilen.brian@mayo.edu. To contact invited critique author Mark L. Friedell, M.D., call John Austin at 816-235-5251 or email austinja@umkc.edu. CHICAGO–  A survey of surgical interns suggests many of them…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Archives of Internal Medicine Study Highlights Loneliness in individuals over 60 years of age appears associated with an increased risk of functional decline and death in a study that included 1,604 participants from the Health and Retirement Study (Online First, see news release below). Living…

Living Alone Associated with Higher Risk of Mortality, Cardiovascular Death

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Media Advisory: To contact corresponding author Deepak L. Bhatt, M.D., M.P.H., call Diane Keefe at 857-203-5879 or email diane.keefe@va.gov. CHICAGO– Living alone was associated with an increased risk of death and cardiovascular death in an international study of stable outpatients at risk of or with…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, JUNE 19, 2012   Viewpoints in This Week’s JAMA   Designing Health Care for the Most Common Chronic Condition—Multimorbidity   Mary E. Tinetti, M.D., of the Yale University School of Medicine,New Haven,Conn., and colleagues write that multimorbidity, the coexistence of multiple chronic diseases or conditions, is the most…

Study Examines Chronic Inflammation in Oral Cavity and HPV Status of Head and Neck Cancers

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Media Advisory: To contact Mine Tezal, D.D.S., Ph.D., call Sara Saldi at 716-645-4593 or email saldi@buffalo.edu. CHICAGO – Among patients with head and neck squamous cell carcinomas, a history of chronic inflammation in the mouth (periodontitis, i.e. gum disease) may be associated with an increased…

Study Suggests Link Between Smoking, Increased Risk of Cutaneous Squamous Cell Carcinoma

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, JUNE 18, 2012 Media Advisory: To contact Jo Leonardi-Bee, Ph.D., email Jo.Leonardi-Bee@nottingham.ac.uk. CHICAGO– Smoking appears to be associated with an increased risk of cutaneous squamous cell carcinoma skin cancer, according to a report of a meta-analysis and review of available medical literature published Online First by Archives of…