Norovirus Outbreaks in Nursing Homes Associated With Increase in Hospitalizations, Risk of Death

EMBARGOED FOR EARLY RELEASE: 11:15 A.M. (CT) THURSDAY, OCTOBER 18, 2012 Media Advisory: To contact Tarak K. Trivedi, B.S., call John Easton at 773-795-5225 or email john.easton@uchospitals.edu. CHICAGO – In a study that included more than 300 Medicare-certified nursing homes, rates of hospitalization and death were substantially increased during outbreaks of norovirus gastroenteritis vs. non-outbreak…

Multivitamin Use Among Middle-Aged, Older Men Results in Modest Reduction in Cancer

EMBARGOED FOR EARLY RELEASE: 9:30 A.M. (CT) WEDNESDAY, OCTOBER 17, 2012 Media Advisory: To contact J. Michael Gaziano, M.D., M.P.H., call Tom Langford at 617-534-1605 or email tlangford@partners.org. CHICAGO – In a randomized trial that included nearly 15,000 male physicians, long-term daily multivitamin use resulted in a modest but statistically significant reduction in cancer after…

Study Identifies Characteristics of Sunbed Users, Motivation for Tanning

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Media Advisory: To contact Sven Schneider, Ph.D., M.A., email Sven.Schneider@medma.uni-heidelberg.de. CHICAGO– A telephone survey of 4,851 individuals in Germany suggests the overall prevalence of sunbed use was nearly 40 percent for participants who had ever used one and 14.6 percent had used a tanning bed…

Archives of Facial Plastic Surgery Study Highlights

  EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012  Archives of Facial Plastic Surgery Study Highlights Dry eye symptoms and chemosis (swelling of the tissues on the surface of the eye) were reported in 26.5 percent and 26.3 percent of patients, respectively, following blepharoplasty (eyelid surgery), according to a study of 892 cases…

Study Suggests Men Diagnosed with ADHD as Children Had Worse Educational, Occupational, Economic, Social Outcomes as Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Media Advisory: To contact Rachel G. Klein, Ph.D., call Allison Clair at 212-404-3753 or email allison.clair@nyumc.org. CHICAGO – Men who were diagnosed as children with attention-deficit/hyperactivity disorder (ADHD) appeared to have significantly worse educational, occupational, economic and social outcomes in a 33-year, follow-up study that compared…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Archives of Neurology Study Highlights While deep brain stimulation of the subthalamic nucleus has been associated with improvement in the symptoms of Parkinson disease (PD), including bradykinesia (a slowness of motion), a study of 24 patients with PD suggests that when stimulation was turned off…

Archives of Otolaryngology–Head & Neck Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Archives of Otolaryngology–Head & Neck Surgery Study Highlights Simulated surgical training appeared to improve technical skills to a proficiency level in otolaryngology residents in a study of 14 residents at two academic medical centers in New York, with eight residents trained to proficiency on an…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012  Archives of Dermatology Study Highlights A telephone survey of 4,851 individuals in Germany suggests the overall prevalence of sunbed use was 39.2 percent for participants who had ever used one and 14.6 percent had used a tanning bed within the last 12 months (Online First,…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Archives of Internal Medicine Study Highlights A study that sought to develop and validate a clinical prediction tool for patients after ischemic stroke suggests that the PLAN score (derived from preadmission comorbidities [co-existing diseases], level of consciousness, age and neurologic deficit) appeared to predict 30-day…

Weight Loss Surgery May be Associated with Increased Substance Use Following Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Media Advisory: To contact Alexis Conason, Psy.D., call 646-841-3652 or email drconason@gmail.com. CHICAGO – Patients who undergo bariatric weight loss surgery may be at increased risk for substance use (drug use, alcohol use and cigarette smoking) following surgery, particularly among patients who undergo laparoscopic Roux-en-Y…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights Researchers in Finland suggest that the risk of long-term consequences from childhood urinary tract infection (UTI) appears to be low after a follow-up study found no cases of impaired renal function or hypertension six to 17 years…

Archives of Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 15, 2012 Archives of Surgery Study Highlights Patients who undergo bariatric weight loss surgery may be at increased risk for substance use (drug use, alcohol use and cigarette smoking) following surgery, particularly among patients who undergo laparoscopic Roux-en-Y gastric bypass surgery who appear to be at increased…

Also Appearing in This Week’s Issue

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 16, 2012 Study Finds Association Between Pseudoephedrine Sales and Illicit Manufacture of Methamphetamine “The illicit production of methamphetamine [a highly addictive stimulant drug] from the precursor pseudoephedrine in clandestine laboratories fuels up to 35 percent of the domestic supply. Public health, law enforcement, and medical associations support…

High-Dose Multivitamin Supplementation Does Not Improve Outcomes For HIV Patients Receiving Antiretroviral Therapy

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 16, 2012 Media Advisory: To contact Sheila Isanaka, Sc.D., call Marge Dwyer at 617-432-8416 or email mhdwyer@hsph.harvard.edu. CHICAGO – Among patients with human immunodeficiency virus (HIV) infection in Tanzania, high-dose multivitamin supplementation after beginning highly active antiretroviral therapy did not reduce the risk of HIV disease progression…

Lower Use of Chloride in Intravenous Fluids For Critically Ill Patients Associated With Decreased Risk of Kidney Injury

  EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 16, 2012 Media Advisory: To contact corresponding author Rinaldo Bellomo, M.D., F.C.I.C.M., email rinaldo.bellomo@austin.org.au. To contact editorial co-author Sushrut S. Waikar, M.D., M.P.H., call Jessica Maki at 617-534-1603 or email jmaki3@partners.org. CHICAGO – In a pilot study assessing the effect of different levels of chloride in…

Study Identifies Strategy for Improved Screening for Type of Hereditary Colorectal Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 16, 2012 Media Advisory: To contact corresponding author Antoni Castells, M.D., Ph.D., email castells@clinic.ub.es. To contact editorial co-author James M. Ford, M.D., call Krista Conger at 650-725-5371 or email kristac@stanford.edu. CHICAGO – In a comparison of strategies to identify individuals with Lynch syndrome, the most common form…

Cholesterol Levels Improving Among U.S. Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 16, 2012 Media Advisory: To contact Margaret D. Carroll, M.S.P.H., call Karen Hunter at 404-639-3286 or email ksh7@cdc.gov. CHICAGO – An analysis of nationally-representative data indicates that between 1988 and 2010 there has been a trend of declining average levels of total cholesterol, non-high-density lipoprotein cholesterol, and…

Archives of Ophthalmology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Archives of Ophthalmology Study Highlights Discussing driving concerns with older patients is the subject of two articles that report the results of a survey of 404 vision care professionals (VCPs) in Michigan (both optometrists and ophthalmologists). In one article, more than 80 percent of VCPs…

Moving from High-Poverty to Low-Poverty Neighborhoods Appears Beneficial for Some Adolescent Girls

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Media Advisory: To contact Theresa L. Osypuk, Sc.D., Sc.M., call Lauren Dibble at 617-373-5460 or email l.dibble@neu.edu. CHICAGO– Although some girls benefited from a program that moved families from high-poverty areas to low-poverty areas, boys and adolescents from families with preexisting health-related vulnerabilities did not…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Archives of Internal Medicine Study Highlights Overall death rates due to human immunodeficiency virus (HIV) infection declined over time between 1993 and 2007 for most men and women by race/ethnicity and educational levels, with the largest absolute decreases for nonwhites because of their higher baseline…

Study Finds Decline in HIV Deaths for Most Men, Women by Race/Ethnicity, Education

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Media Advisory: To contact author Edgar P. Simard, Ph.D., M.P.H., call David Sampson at 213-840-7525 or email David.Sampson@cancer.org. To contact commentary author William Cunningham, M.D., M.P.H., call Enrique Rivero at 310-794-2273 or email ERivero@mednet.ucla.edu. CHICAGO – Overall death rates due to human immunodeficiency virus (HIV)…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 9, 2012 Study Examines Off-Label Use of Bone Protein For Pediatric Spinal Surgery Arthrodesis (the surgical fixation of a joint to promote bone fusion) of the spine is frequently performed in children. Although nonunion occurs frequently in adults, children rarely experience nonunion. Bone morphogenetic proteins (BMPs) are…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A study of children in theNew Bedford,Mass., area suggests that low-level prenatal mercury exposure may be associated with a greater risk of attention-deficit/hyperactivity disorder (ADHD)-related behaviors and that fish consumption during pregnancy may be associated with a…

Level of Hormone Associated With Increased Risk of Diabetes, Cardiovascular Disease, Breast Cancer and Death

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 9, 2012 Media Advisory: To contact Olle Melander, M.D., Ph.D., email olle.melander@med.lu.se. CHICAGO – Plasma levels of proneurotensin are associated with the development of diabetes, cardiovascular disease, cardiovascular and total mortality, and breast cancer in women during long-term follow-up, according to a study in the October 10…

Prenatal Mercury Exposure May be Associated with Risk of ADHD-Related Behaviors; Fish Consumption May be Associated with Lower Risk

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 8, 2012 Media Advisory: To contact Sharon K. Sagiv, Ph.D., M.P.H., call Tom Langford at 617-534-1605 or tlangford@partners.org. To contact editorial author Bruce P. Lanphear, M.D., M.P.H., call 778-782-8650 or email blanphear@sfu.ca. CHICAGO– A study of children in the New Bedford, Mass., area suggests that low-level prenatal…

Rates of Procedures Such as Angioplasty Lower in States With Public Reporting of Outcomes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 9, 2012 Media Advisory: To contact Karen E. Joynt, M.D., M.P.H., call Todd Datz at 617-432-8413 or email tdatz@hsph.harvard.edu.  To contact editorial author Maura Moscucci, M.D., M.B.A., call Lisa Worley at 305-243-5184 or email lworley2@med.miami.edu. CHICAGO – In an analysis that included nearly 100,000 Medicare patients who…

Vigorous Physical Activity May Increase Risk of Bleeding for Children With Hemophilia

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 9, 2012 Media Advisory: To contact Carolyn R. Broderick, M.B.B.S., email c.broderick@unsw.edu.au. To contact Marilyn J. Manco-Johnson, M.D., call Jacque Montgomery at 303-928-9093 or email Jacque.Montgomery@ucdenver.edu. CHICAGO – In children and adolescents with hemophilia, vigorous physical activity was associated with an elevated risk of bleeding, although it…

Use of Fresh Red Blood Cells for Transfusions for Premature Infants Does Not Improve Outcomes

EMBARGOED FOR EARLY RELEASE: 8 A.M. (CT) MONDAY, OCTOBER 8, 2012 Media Advisory: To contact Dean A. Fergusson, M.H.A., Ph.D., call Paddy Moore at 613-737-8899, ext. 73687, or email padmoore@ohri.ca. CHICAGO – Among premature, very low-birth-weight infants requiring a transfusion, use of fresh red blood cells (RBCs) compared with standard RBC transfusion practice did not…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 2, 2012 Challenges at the Intersection of Team-Based and Patient-Centered Health Care – Insights From an IOM Working Group Matthew K. Wynia, M.D., M.P.H., of the American Medical Association, Chicago, and colleagues write that team-based health care may help the United States achieve improved health and improved…

Cardiac Medication May Help Reduce Stiffness Caused by Certain Muscle Diseases

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 2, 2012 Media Advisory: To contact corresponding author Richard J. Barohn, M.D., call C.J. Janovy at 913-588-2598 or email cjanovy@kumc.edu. To contact editorial co-author Eric P. Hoffman, Ph.D., call Paula Darte at 202-821-6357 or email pdarte@ChildrensNational.org. CHICAGO – Preliminary research finds that for patients with nondystrophic myotonias…

Patients With Rheumatoid Arthritis Appear To Be At Increased Risk For Blood Clots

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 2, 2012 Media Advisory: To contact Marie E. Holmqvist, M.D., Ph.D., email marie.holmqvist@ki.se. CHICAGO – A study that included more than 45,000 residents of Sweden with rheumatoid arthritis finds that individuals with this disease had an associated higher risk of venous thromboembolism (a blood clot that forms…

Beta-Blocker Use Not Associated With Lower Risk of Cardiovascular Events

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 2, 2012 Media Advisory: To contact Sripal Bangalore, M.D., M.H.A., call Allison Clair at 212-404-3753 or email allison.clair@nyumc.org. CHICAGO – Among patients with either coronary artery disease (CAD) risk factors only, known prior heart attack, or known CAD without heart attack, the use of beta-blockers was not…

Vitamin D Supplementation Does Not Reduce Rate or Severity of Colds

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, OCTOBER 2, 2012 Media Advisory: To contact David R. Murdoch, M.D., email david.murdoch@otago.ac.nz. To contact editorial author Jeffrey A. Linder, M.D., M.P.H., call Marjorie Montemayor-Quellenberg at 617-534-2208 or email mmontemayor-quellenberg@partners.org. CHICAGO – Although some data have suggested a possible inverse association between serum vitamin D levels and the…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Archives of Neurology Study Highlights A study of 84 patients with multiple sclerosis (MS) and 24 healthy controls that used a high-resolution imaging technique to measure retinal layer thickness suggests that those retinal measures reflect global central nervous system pathology in patients with MS. The…

Psychiatric Disorders May Persist in Some Young People After Detention

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Media Advisory: To contact Linda A. Teplin, Ph.D., call Marla Paul at 312-503-8928 or email marla-paul@northwestern.edu. CHICAGO– A study of juveniles detained in Chicagosuggests that more than 45 percent of males and nearly 30 percent of females had one or more psychiatric disorders with associated…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Archives of General Psychiatry Study Highlights A study of juveniles detained in Chicago suggests that more than 45 percent of males and nearly 30 percent of females had one or more psychiatric disorders with associated impairment five years after detention (See news release below). A…

Study Suggests High Use of Medicare Skilled Nursing Benefit at End of Life

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Media Advisory: To contact corresponding author Alexander K. Smith, M.D., M.S., M.P.H., call Jason Bardi at 415-502-4608 or email jason.bardi@ucsf.edu. To contact commentary author Peter A. Boling, M.D., call Cheryle Rodriguez at 804-827-0889 or email clrodriguez@vcu.edu. CHICAGO– Almost one-third of older adults received care in…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Archives of Internal Medicine Study Highlights Almost one-third of older adults received care in a skilled nursing facility in the last six months of life under the Medicare posthospitalization benefit, according to a study of more than 5,000 Medicare participants who died (Online First, see…

Study Examines Safety of Quadrivalent HPV Vaccine Given to Females

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, OCTOBER 1, 2012 Media Advisory: To contact corresponding author Nicola P. Klein, M.D., Ph.D., call Maureen McInaney at 510-891-3173 or email maureen.mcinaney@kp.org. CHICAGO– A study of girls and young women in Californiasuggests that the quadrivalent human papillomavirus vaccine (HPV4) appeared to be associated with syncope (fainting) on the…

Viewpoints in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 25, 2012 Bringing Diagnosis Into the Quality and Safety Equations Mark L. Graber, M.D., of RTI International, St. James, N.Y., and colleagues suggest that cases of delayed, missed and incorrect diagnosis are common, with an incidence in the range of 10 percent to 20 percent, and that…

Use of Corticosteroid For Children Undergoing Tonsillectomy Does Not Appear to Increase Risk of Serious Bleeding

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 25, 2012 Media Advisory: To contact corresponding author Christopher J. Hartnick, M.D., call Mary Leach at 617-573-4170 or email Mary_Leach@meei.harvard.edu. CHICAGO – Administration of the corticosteroid dexamethasone to children during a tonsillectomy was not associated with excessive, serious bleeding events following surgery compared to patients who received…

Study Examines Usage, Outcomes of Knee Replacement Procedures Among Medicare Patients

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 25, 2012 Media Advisory: To contact Peter Cram, M.D., M.B.A., call Tom Moore at 319-356-3945 or email thomas-moore@uiowa.edu. To contact editorial co-author Joseph D. Zuckerman, M.D., call Craig Andrews at 212-404-3511 or email Craig.Andrews@nyumc.org. CHICAGO – There has been an increase in total knee arthroplasty (TKA; knee…

Study Examines Delayed, Misdiagnosis of Sporadic Jakob-Creutzfeldt Disease

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 24, 2012 Media Advisory: To contact corresponding author Michael D. Geschwind, M.D., Ph.D., call Jason Bardi at 415-502-4608 or email jason.bardi@ucsf.edu. To contact editorial author Richard J. Caselli, M.D., call Jim McVeigh at 480-301-4222 or email mcveigh.jim@mayo.edu. CHICAGO– A medical record review study of 97 patients with…

Study Links Active Video Gaming with Higher Energy Expenditure in Children

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 24, 2012 Media Advisory: To contact corresponding author Michael M. Morris, M.Sc., email m.morris@chester.ac.uk. CHICAGO – Compared with rest and sedentary video game play, active video gaming with dancing and boxing were associated with increased heart rate, oxygen uptake and energy expenditure in a study of 18…

Study Analyzes Variations in Antibiotic Prescribing Among Older Patients

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 24, 2012 Media Advisory: To contact author Yuting Zhang, Ph.D., call Allison Hydzik or Cyndy McGrath at 412-647-9975 or email hydzikam@upmc.edu and mcgrathc3@upmc.edu. To contact commentary author Ralph Gonzales, M.D., M.S.P.H., call Jason Bardi at 415-502-4608 or email jason.bardi@ucsf.edu. CHICAGO– A study of Medicare data suggests there…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 24, 2012 Archives of Internal Medicine Study Highlights Two articles examine antibiotic prescribing patterns. A study of Medicare data suggests there was wide variation in antibiotic prescribing for older patients based on geography and the season in which prescriptions for the medication were written (Online First, see…

Archives of Otolaryngology–Head & Neck Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Archives of Otolaryngology–Head & Neck Surgery Study Highlights Among patients with oral cancers treated primarily with surgery from 1985 to 2009 at a single-institution tertiary care cancer center, there was a progressive decrease in the prevalence of tobacco users. A similar trend was observed for…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A telephone interview study of 1,050 pairs of mothers and their third-grade children in the southeastern United States suggests the notion that early exposure to alcohol can be beneficial for children has a strong foothold among some…

Archives of Facial Plastic Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012  Archives of Facial Plastic Surgery Study Highlights Endoscopic forehead-lift appears to enable long-lasting results, and patients receiving the treatment reported feeling satisfied, according to a review of 143 medical records of patients who underwent endoscopic forehead-lift between 1994 and 2007. A total of 98 patients…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012  Archives of Dermatology Study Highlights A study of 201 patients in Spain that evaluated differences in the initial prognosis of patients with cutaneous melanoma managed by teledermatology (TD) compared with non-TD referral systems suggests that the frequency of melanoma with a favorable initial prognosis was…

Resuming Warfarin After Gastrointestinal Tract Bleeding Associated with Lower Risk for Thrombosis, Death

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Media Advisory: To contact author Daniel M. Witt, Pharm.D., F.C.C.P., B.C.P.S., call Amy Whited at 303-344-7518 or email Amy.L.Whited@kp.org. To contact commentary author Daniel J. Brotman, M.D., call Stephanie Desmon at 410-955-8665 or email sdesmon1@jhmi.edu. CHICAGO– A study of patients treated with the anticoagulant medication…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Archives of Internal Medicine Study Highlights A study of patients treated with the anticoagulant medication warfarin suggests that resuming warfarin therapy after gastrointestinal tract bleeding was associated with lower risk for thrombosis (blood clot) and death (Online First, see news release below). A study suggests…

Archives of Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Archives of Surgery Study Highlights A study comparing bariatric surgical procedures for obesity suggests that even though undergoing the less commonly used biliopancreatic diversion/duodenal switch (DS) may be associated with higher early risks compared with gastric bypass (GB), the DS appears to achieve better weight…

Study Compares Duodenal Switch vs. Gastric Bypass for Morbid Obesity

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 17, 2012 Media Advisory: To contact corresponding author Matthew J. Martin, M.D., call Carrie Bernard at 253-968-2968 or email carrie.bernard@us.army.mil. To contact critique author Alec C. Beekley, M.D., call Katie Krauss at 215-955-5507 or email katharine.krauss@jefferson.edu. CHICAGO – A study comparing bariatric surgical procedures for obesity suggests…

Also Appearing in This Week’s Obesity Theme Issue

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, SEPTEMBER 18, 2012 Higher Amounts of Aerobic Exercise By Overweight Children Reduces Risk of Diabetes Child obesity and overweight are epidemic among U.S. children, with a third of elementary school-aged children being overweight or obese. Childhood obesity is associated with a number of adverse conditions formerly thought…

Government Can Play Important Role in Obesity Epidemic

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, SEPTEMBER 18, 2012 Media Advisory: To contact Thomas A. Farley, M.D., M.P.H., call Jean Weinberg at 347-396-4177 or email jweinberg@health.nyc.gov. NEW YORK – Addressing the obesity epidemic by preventing excess calorie consumption with government regulation of portion sizes is justifiable and could be an effective measure to…

Obese Adults With Excess Abdominal Fat and Insulin Resistance Appear to Have Higher Risk of Developing Type 2 Diabetes

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, SEPTEMBER 18, 2012 Media Advisory: To contact James A. de Lemos, M.D., call Lisa Warshaw at 214-648-9349 or email lisa.warshaw@utsouthwestern.edu. NEW YORK – Obese adults with excess visceral fat (fat located inside the abdominal cavity, around the body’s internal organs) and biomarkers of insulin resistance had an…

Over Long-Term, Gastric Bypass Surgery Associated With Higher Rate of Diabetes Remission, Improvement in Cardiovascular Risk Factors

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, SEPTEMBER 18, 2012 Media Advisory: To contact Ted D. Adams, Ph.D., M.P.H., call Jennifer Barrett at 801-408-2182 or email jennifer.barrett@imail.org. To contact editorial author Anita P. Courcoulas, M.D., M.P.H., call Amy Dugas Rose at 412-586-9776 or email dugasak@upmc.edu. NEW YORK – Severely obese patients who had Roux-en-Y…

Higher Levels of BPA in Children and Teens Associated With Obesity

EMBARGOED FOR EARLY RELEASE: 10 A.M. (ET) TUESDAY, SEPTEMBER 18, 2012 Media Advisory: To contact Leonardo Trasande, M.D., M.P.P., call Jessica Guenzel at 212-404-3591 or email Jessica.Guenzel@nyumc.org. NEW YORK – In a nationally representative sample of nearly 3,000 children and adolescents, those who had higher concentrations of urinary bisphenol A (BPA), a manufactured chemical found…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 11, 2012 Study Analyzes Changes in Pharmaceutical Advertising Following Shift to OTC Status “The U.S. Food and Drug Administration (FDA) regulates prescription drug advertising, including requirements to provide consumers with a ‘fair balance’ of risks and benefits. When prescription drugs switch to over-the-counter (OTC) status, regulatory oversight…

Study Examines Cost-Savings of Physician Group Practice Program That is Similar to Proposed Programs of Accountable Care Organizations

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 11, 2012 Media Advisory: To contact Carrie H. Colla, Ph.D., call Annmarie Christensen at 603-653-0897 or email annmarie.christensen@dartmouth.edu. To contact editorial author Donald M. Berwick, M.D., M.P.P., email donberwick1@gmail.com. CHICAGO – In an analysis of the cost-savings achieved by an earlier pilot program, the Medicare Physician Group…

Technique Using Computed Tomography Associated With Improved Detection of Lymph Node Metastasis in Patients With Melanoma

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 11, 2012 Media Advisory: To contact corresponding author Joachim Klode, M.D., email joachim.klode@uk-essen.de. CHICAGO – Preoperative 3-dimensional visualization of sentinel lymph nodes (SLNs) with a technique known as single-photon emission computed tomography/computed tomography was associated with a higher rate of detection of positive SLNs and a higher…

Research Finds Little Difference in Outcomes Among Strategies to Adjust Asthma Therapy in Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 11, 2012 Media Advisory: To contact William J. Calhoun, M.D., call Raul Reyes at 409-747-0794 or email rareyes@utmb.edu. To contact editorial co-author George T. O’Connor, M.D., M.S., call Gina DiGravio at 617-638-8480 or email gina.digravio@bmc.org. CHICAGO – Among adults with asthma controlled with low-dose inhaled corticosteroid therapy,…

Omega-3 Fatty Acid Supplementation Not Associated With Lower Risk of Major Cardiovascular Disease Events

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 11, 2012 Media Advisory: To contact corresponding author Moses S. Elisaf, M.D., Ph.D., F.A.S.A., F.R.S.H., email egepi@cc.uoi.gr. CHICAGO – In a study that included nearly 70,000 patients, supplementation with omega-3 polyunsaturated fatty acids was not associated with a lower risk of all-cause death, cardiac death, sudden death,…

Archives of Ophthalmology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Archives of Ophthalmology Study Highlights An observational cross-sectional study of 1,936 patients of the Chronic Renal Insufficiency Cohort found an association between retinopathy (a persistent or acute disorder involving the retina) and decreased kidney function. The authors suggest that retinovascular pathology may reflect renal disease,…

Vigorous Physical Activity Associated with Reduced Cardiometabolic Risk Factors in Youth

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Media Advisory: To contact corresponding author Jonathan McGavock, Ph.D., call 204-480-1359 or email jmcgavock@mich.ca.  CHICAGO– A study of Canadian youth suggests that vigorous physical activity was associated with reduced cardiometabolic risk factors, such as body mass index z score (BMI-z), waist circumference, systolic blood pressure…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Archives of Neurology Study Highlights Treatment with angiotensin receptor blockers (ARBs; group of medications used in treatment of hypertension, diabetic nephropathy and congestive heart failure) among persons with hypertension is associated with less amyloid accumulation in the brain and a decreased likelihood of post-mortem neuropathologic…

Study Links Electrolyte Disorder Hyponatremia with Increased Risk of Death, Complications Following Surgery

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Media Advisory: To contact corresponding author David W. Bates, M.D., M.Sc., call Tom Langford at 617-534-1605 or email tlangford@partners.org. To contact corresponding commentary author Joseph A. Vassalotti, M.D., call Christie Corbett at 212-241-9200 or email christie.corbett@mountsinai.org. CHICAGO – An observational study of nearly 1 million…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A study of Canadian youth suggests that vigorous physical activity was linked to reduced cardiometabolic risk factors, such as body mass index z score (BMI-z), waist circumference, systolic blood pressure and increased cardiorespiratory fitness (Online First, see…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Archives of Internal Medicine Study Highlights An observational study of nearly 1 million patients who underwent surgery suggests that preoperative hyponatremia (an electrolyte disorder in which sodium levels in the blood are low) was associated with an increased risk of complications and death within 30…

Study Suggests Acupuncture May be Better Than No Acupuncture, Sham Acupuncture for Treatment of Chronic Pain

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 10, 2012 Media Advisory: To contact author Andrew J. Vickers, D.Phil., call Caitlin Hool at 212-639-3573 or email hoolc@mskcc.org. To contact commentary author Andrew L. Avins, M.D., M.P.H., call Maureen McInaney at 510-891-3173 or email maureen.mcinaney@kp.org. CHICAGO– An analysis of patient data from 29 randomized controlled trials…

Also Appearing in This Week’s JAMA

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 4, 2012 Prone Position During Breast Cancer Radiation Therapy Associated With Reduced Amount of Irradiation to Lung, Heart Radiation therapy to the breast contributes to improved outcomes in breast cancer patients after breast preservation surgery. “However, whole breast radiotherapy is associated with damage to the heart and…

Use of Biologic Therapy for Rheumatoid Arthritis Not Significantly Associated With Increased Risk of Malignancy

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 4, 2012 Media Advisory: To contact corresponding author Maria E. Suarez-Almazor, M.D., Ph.D., call Julie Penne at 713-792-0662 or email jpenne@mdanderson.org. CHICAGO – Although there are concerns regarding the potential development of malignancies in patients with rheumatoid arthritis who are receiving treatment with biologic response modifiers (BRMs),…

Study Evaluates Association Between Clopidogrel Use and Mortality Risk in Heart Attack Patients With Diabetes

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 4, 2012 Media Advisory: To contact Charlotte Andersson, M.D., Ph.D., email ca@heart.dk. To contact editorial author Deepak L. Bhatt, M.D., M.P.H., call Lori Schroth at 617-534-1604 or email ljschroth@partners.org. CHICAGO – In a study that included nearly 60,000 patients with a first-time heart attack, patients with diabetes…

Cardiac Study Evaluates Prevalence of Unrecognized Heart Attacks Among Older Adults

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 4, 2012 Media Advisory: To contact corresponding author Andrew E. Arai, M.D., call Nick Zagorski at 301-496-4236 or email nicholas.zagorski@nih.gov. CHICAGO – Using cardiac magnetic resonance imaging among older adults in Iceland, researchers estimated the prevalence of unrecognized heart attacks, which was associated with an increased risk…

Study Suggests Possible Association Between Cardiovascular Disease, Chemical Exposure

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Media Advisory: To contact Anoop Shankar, M.D., Ph.D., call Amy Johns at 304-293-1412 or email johnsa@wvuhealthcare.com. To contact commentary author Debabrata Mukherjee, M.D., M.S., call Laura Gallegos at 915-309-5647 or email laura.gallegos@ttuhsc.edu. CHICAGO– Exposure to perfluorooctanoic acid (PFOA), a manmade chemical used in the manufacture…

Stiffening of Aortic Wall Linked With Increased Risk of High Blood Pressure

EMBARGOED FOR RELEASE: 3 P.M. (CT) TUESDAY, SEPTEMBER 4, 2012 Media Advisory: To contact corresponding author Gary F. Mitchell, M.D., call 781-255-6930 or email garyfmitchell@gmail.com. To contact editorial author Debabrata Mukherjee, M.D., M.S., call Laura Gallegos at 915-309-5647 or email laura.gallegos@ttuhsc.edu. CHICAGO – An analysis of the relationship between several vascular function measures and blood…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Archives of Internal Medicine Study Highlights Exposure to perfluorooctanoic acid (PFOA), a manmade chemical used in the manufacture of some common household products, appears to be associated with cardiovascular disease and peripheral arterial disease in a study of 1,216 individuals (Online First, see news release…

Study Examines Association Between Parkinson Disease, Cancer

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Media Advisory: To contact corresponding author Lisa A. Cannon-Albright, Ph.D., call Kathy Wilets at 801-581-5717 or email kathy.wilets@hsc.utah.edu. To contact editorial author Walter A. Rocca, M.D., M.P.H., call Brian Kilen at 507-284-5005 or email newsbureau@mayo.edu. CHICAGO– A study that used a Utahgenealogic database and a…

Archives of Neurology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Archives of Neurology Study Highlights A study that used a Utah genealogic database and a statewide cancer registry to examine the relationship between Parkinson disease (PD) and cancer suggests an increased risk of prostate cancer and melanoma in patients with PD and their relatives (Online…

Prenatal Maternal Smoking Associated With Increased Risk of Adolescent Obesity

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Media Advisory: To contact corresponding author Zdenka Pausova, M.D., call Caitlin McNamee-Lamb at 416-813-7654, ext. 1436 or email caitlin.mcnamee-lamb@sickkids.ca. CHICAGO – Prenatal exposure to maternal cigarette smoking appears associated with an increased risk for adolescent obesity, and is possibly related to subtle structural variations in…

Archives of General Psychiatry Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Archives of General Psychiatry Study Highlights Prenatal exposure to maternal cigarette smoking appears associated with an increased risk for adolescent obesity and is possibly related to subtle structural variations in the brain that create a preference for eating fatty foods (Online First; see news release…

Study Details Bullying Involvement for Adolescents with Autism Spectrum Disorder

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Media Advisory: To contact Paul R. Sterzing, Ph.D., M.S.S.W., call Yasmin Anwar at 510-643-7944 or email yanwar@berkeley.edu. CHICAGO– A study based on information collected from 920 parents suggests an estimated 46.3 percent of adolescents with an autism spectrum disorder were the victims of bullying, according…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, SEPTEMBER 3, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights A study based on information collected from 920 parents suggests an estimated 46.3 percent of adolescents with an autism spectrum disorder were the victims of bullying (Online First, see news release below). While many children with pleural…

Study Examines Factors Associated With Improvement in Survival From Heart Attack in France

EMBARGOED FOR EARLY RELEASE: 1 A.M. (CT) MONDAY, AUGUST 27, 2012 Media Advisory: To contact corresponding author Nicolas Danchin, M.D., Ph.D., email nicolas.danchin@egp.aphp.fr. CHICAGO – The overall rate of death in patients hospitalized with ST-segment elevation myocardial infarction (STEMI; a certain pattern on an electrocardiogram following a heart attack) decreased from 1995 to 2010 in…

Diagnostic Test Shows Potential As Method to Noninvasively Identify Significant Coronary Artery Disease

EMBARGOED FOR EARLY RELEASE: 1 A.M. (CT) SUNDAY, AUGUST 26, 2012 Media Advisory: To contact James K. Min, M.D., call Sally Stewart at 310-423-4768 or email sally.stewart@cshs.org. To contact editorial author Manesh R. Patel, M.D., call Sarah Avery at 919-660-1306 or email sarah.avery@duke.edu. CHICAGO – Among patients with suspected or known coronary artery disease, use…

Study Examines Use of 5 Cerebrospinal Fluid Biomarkers for Differentiating Parkinson Disease from Common Dementia

  EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Media Advisory: To contact Sara Hall, M.D., email sara.hall@med.lu.se or to contact corresponding author Oskar Hansson, M.D., Ph.D., email oskar.hansson@med.lu.se. To contact editorial author Richard J. Perrin, M.D., Ph.D., call Judy Martin Finch at 314-286-0105 or email martinju@wustl.edu. CHICAGO – A study of cerebrospinal…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights An observational study at two urban primary care clinics with 254 parents of 3- and 4-year-old children suggests that 1 in 4 low-income preschool-aged children screened positive for social-emotional problems, and most parents were open to referrals…

Study Reviews Discontinuation of LABA Therapy in Patients with Asthma

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Media Advisory: To contact corresponding author Thomas B. Casale, M.D., call Deborah Daley at 402-280-1786 or email deborahdaley@creighton.edu. To contact corresponding commentary author Andrew F. Shorr, M.D., M.P.H., call So Young Pak at 202-877-2748 or email soyoung.pak@medstar.net. CHICAGO – A review of five clinical trials…

Study Compares Cardiovascular Events, Stroke in Patients Prescribed Beta-Blockers for Hypertension

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Media Advisory: To contact Emily D. Parker, M.P.H., Ph.D., call Mary Van Beusekom at 952-967-7361 or email Mary.B.VanBeusekom@HealthPartners.com. To contact corresponding commentary author James S. Floyd, M.D., M.S., call Leila Gray 206-685-0381 or email leilag@uw.edu. CHICAGO – A study that compared the incidence of myocardial…

Study Links Fitness in Midlife with Lower Risk of Chronic Diseases

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Media Advisory: To contact corresponding author Jarrett D.Berry, M.D., M.S., call Remekca Owens at 214-648-3404 or email remekca.owens@utsouthwestern.edu. To contact commentary author Diane E. Bild, M.D., M.P.H., call the National Heart, Lung and Blood Institute communications office at 301-496-4236 or email nhlbi_news@nhlbi.nih.gov. CHICAGO– Fitness in…

Archives of Internal Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 27, 2012 Archives of Internal Medicine Study Highlights Fitness in midlife appears to be associated with a lower risk of common chronic health conditions later in life in men and women older than 65 years and enrolled in Medicare (Online First, see news release below). A study…

Archives of Otolaryngology–Head & Neck Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Archives of Otolaryngology–Head & Neck Surgery Study Highlights A study of 46 otolaryngology residency program graduates that compared overall faculty rating with their residency applications suggests that excellence in a team sport, instead of the typical factors used during resident selection, was correlated with higher…

Study Examines Risk of Heart Attack Associated with Various Psoriasis Treatments

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Media Advisory: To contact Jashin J. Wu, M.D., call Sandra Hernandez-Millett at 626-405-5384 or email sandra.d.hernandez-millett@kp.org. CHICAGO– Use of tumor necrosis factor (TNF) inhibitors for treatment of psoriasis is associated with a significantly reduced risk for heart attack (myocardial infarction) compared to other forms of…

Archives of Dermatology Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012  Archives of Dermatology Study Highlights Use of tumor necrosis factor (TNF) inhibitors for treatment of psoriasis is associated with a significantly reduced risk for heart attack (myocardial infarction) compared to other forms of treatment (Online First, see news release below). A study of 132 adults…

Study Projects Increases in Health Care Costs, Infections with Declines in Male Circumcision

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Media Advisory: To contact Aaron A.R. Tobian, M.D., Ph.D., call David Marchat 410-955-1534 or email dmarch1@jhmi.edu. To contact editorial author Arleen A. Leibowitz, Ph.D., call Alex Boekelheide at 310-206-0159 or email alex.boekelheide@publicaffairs.ucla.edu. CHICAGO – Using a computer-based simulation model, researchers project that a continued decline…

Archives of Pediatrics & Adolescent Medicine Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Archives of Pediatrics & Adolescent Medicine Study Highlights Using a computer-based simulation model, researchers project that a continued decline in male circumcision rates in the United States to levels in Europe, where the procedure is not routinely covered by insurance, may be associated with increased…

Archives of Surgery Study Highlights

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Archives of Surgery Study Highlights A study of 986 patients with gallbladder polyps detected through ultrasonography suggests that polyps between 5 and 10 mm should be monitored with ultrasonography surveillance, while polyps greater than 10 mm or showing an increase in size should be removed…

Survey Finds Symptoms of Burnout Common Among U.S. Physicians

EMBARGOED FOR RELEASE: 3 P.M. (CT), MONDAY, AUGUST 20, 2012 Media Advisory: To contact author Tait D. Shanafelt, M.D., call the Mayo Clinic Department of Public Affairs at 507-284-5005 or email newsbureau@mayo.edu. CHICAGO– A national survey of 7,288 physicians (26.7 percent participation rate) finds that 45.8 percent of physicians reported at least one symptom of…