Mothers Taking Folic Acid Around Conception Associated With A Lower Risk Of Autistic Disorders In Their Children

Read the Video Script
Print

Mothers Taking Folic Acid Around Conception Associated With A Lower Risk Of Autistic Disorders In Their Children

INTRO: It is generally recommended that women who are planning to become pregnant take a daily supplement of folic acid. Taking this supplement has been associated with reduced risk of neurodevelopmental disorders in children. A new study examined whether there was an association between a mother’s taking folic acid before and after becoming pregnant and a child’s risk of developing autism.  Catherine Dolf has more in this week’s JAMA Report.

VIDEO

B-ROLL

Folic acid pills being poured out of bottle, pre-natal vitamins

AUDIO

VO

FOLIC ACID IS A COMMON SUPPLEMENT FOUND IN GREEN LEAFY VEGETABLES AND IN MOST PRE-NATAL VITAMINS.

AUDIO

SOT/FULL Super @:05 Ezra Susser, M.D., Dr. P.H., – Mailman School of Public Health, Columbia University Runs:08

“It was proven that folic acid supplements around the time of pregnancy prevent neural tube defects.”

AUDIO

SOT/FULL Super @:13 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:13

“The neural tube is the origin of the human brain in the fetus and closes very early in development and the neural tube defect is when this tube doesn’t close properly.”

(Video covering 2nd half of bite: Patient getting ultrasound)

VIDEO

B-ROLL

Folic acid pills, pregnant women getting blood pressure checked,  Dr. Surén and Dr. Susser talking, mothers and young children walking outside

AUDIO

VO

SINCE TAKING THE SUPPLEMENT BEFORE OR SOON AFTER BECOMING PREGNANT HAS BEEN SHOWN TO PROTECT EARLY STAGES OF BRAIN DEVELOPMENT, RESEARCHERS WANTED TO KNOW WHETHER THERE WAS AN ASSOCIATION BETWEEN A MOTHER’S TAKING FOLIC ACID AND THE RISK OF HER CHILD DEVELOPING AUTISM.

DR. PÅL (PAUL) SURÉN FROM THE NORWEGIAN INSTITUTE OF PUBLIC HEALTH AND DR. EZRA SUSSER FROM THE MAILMAN SCHOOL OF PUBLIC HEALTH AT COLUMBIA UNIVERSITY AND CO-AUTHORS STUDIED SEVERAL THOUSAND NORWEGIAN MOTHERS AND CHILDREN PARTICIPATING IN A POPULATION BASED STUDY.

AUDIO

SOT/FULL Super @:50 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:09

“Mothers were recruited during pregnancy and in one of the questionnaires we asked them to record all the dietary supplements that they were using.”

(Video Covering 2nd half of bite: pregnant women filling out survey, cu of survey)

VIDEO

B-ROLL

Mothers and children walking

AUDIO

VO

AFTER THE CHILDREN WERE BORN RESEARCHERS THEN IDENTIFIED CASES OF AUTISM OCCURING AMONG THEM.

AUDIO

SOT/FULL Super @1:04 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:10

“We went back to the data we had from early pregnancy and compared those mothers who had taken folic acid to those who hadn’t taken any folic acid.”

VIDEO

GXF FULL JAMA COVER

AUDIO

VO

THE STUDY APPEARS IN JAMA, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

AUDIO

SOT/FULL Super @1:18 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:10

“The women who took folic acid supplements in early pregnancy had a substantial reduction in risk of having a child with autism, the reduction was 40 percent.”

(Video covering 1st half of bite: folic acid pills)

AUDIO

SOT/FULL Super @1:29 Ezra Susser, M.D., Dr. P.H., – Mailman School of Public Health, Columbia University Runs:17

“There’s a sensitive period in which folic acid supplements need to be taken in order to reduce the risk of autism the period begins before pregnancy and continues approximately two months after pregnancy.”

(Video covering 2nd half of bite: pregnant women’s stomach, pregnant women getting ultrasound)

VIDEO

B-ROLL

Folic acid pills, pregnant stomach, pre-natal vitamins

AUDIO

VO

ALSO, MOTHERS WHO BEGAN TAKING THE SUPPLEMENT AT 22 WEEKS OR MID PREGNANCY COMPARED TO THOSE WHO DID NOT TAKE IT AT THAT TIME SHOWED NO ASSOCIATION WITH A LOWER RISK OF AUTISM. THE SAME WAS TRUE WITH WOMEN WHO TOOK FISH OIL SUPPLEMENTS.

AUDIO

SOT/FULL Super @1:57 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:08

“This provides an additional reason to take folic acid supplements and it underlines the importance of starting early before the pregnancy has started.”

(Video covering 2nd half of bite: mothers and kids walking)

B-ROLL

Folic acid pills

AUDIO

VO

CATHERINE DOLF, THE JAMA REPORT.

TAG:: RESEARCHERS SAY ALTHOUGH THE STUDY OUTCOME IS STRONG IT IS NOT CONCLUSIVE AND REQUIRES MORE INVESTIGATION.

February 13, 2013

INTRO: It is generally recommended that women who are planning to become pregnant take a daily supplement of folic acid. Taking this supplement has been associated with reduced risk of neurodevelopmental disorders in children. A new study examined whether there was an association between a mother’s taking folic acid before and after becoming pregnant and a child’s risk of developing autism.  Catherine Dolf has more in this week’s JAMA Report.

VIDEO

B-ROLL

Folic acid pills being poured out of bottle, pre-natal vitamins

AUDIO

VO

FOLIC ACID IS A COMMON SUPPLEMENT FOUND IN GREEN LEAFY VEGETABLES AND IN MOST PRE-NATAL VITAMINS.

AUDIO

SOT/FULL Super @:05 Ezra Susser, M.D., Dr. P.H., – Mailman School of Public Health, Columbia University Runs:08

“It was proven that folic acid supplements around the time of pregnancy prevent neural tube defects.”

AUDIO

SOT/FULL Super @:13 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:13

“The neural tube is the origin of the human brain in the fetus and closes very early in development and the neural tube defect is when this tube doesn’t close properly.”

(Video covering 2nd half of bite: Patient getting ultrasound)

VIDEO

B-ROLL

Folic acid pills, pregnant women getting blood pressure checked,  Dr. Surén and Dr. Susser talking, mothers and young children walking outside

AUDIO

VO

SINCE TAKING THE SUPPLEMENT BEFORE OR SOON AFTER BECOMING PREGNANT HAS BEEN SHOWN TO PROTECT EARLY STAGES OF BRAIN DEVELOPMENT, RESEARCHERS WANTED TO KNOW WHETHER THERE WAS AN ASSOCIATION BETWEEN A MOTHER’S TAKING FOLIC ACID AND THE RISK OF HER CHILD DEVELOPING AUTISM.

DR. PÅL (PAUL) SURÉN FROM THE NORWEGIAN INSTITUTE OF PUBLIC HEALTH AND DR. EZRA SUSSER FROM THE MAILMAN SCHOOL OF PUBLIC HEALTH AT COLUMBIA UNIVERSITY AND CO-AUTHORS STUDIED SEVERAL THOUSAND NORWEGIAN MOTHERS AND CHILDREN PARTICIPATING IN A POPULATION BASED STUDY.

AUDIO

SOT/FULL Super @:50 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:09

“Mothers were recruited during pregnancy and in one of the questionnaires we asked them to record all the dietary supplements that they were using.”

(Video Covering 2nd half of bite: pregnant women filling out survey, cu of survey)

VIDEO

B-ROLL

Mothers and children walking

AUDIO

VO

AFTER THE CHILDREN WERE BORN RESEARCHERS THEN IDENTIFIED CASES OF AUTISM OCCURING AMONG THEM.

AUDIO

SOT/FULL Super @1:04 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:10

“We went back to the data we had from early pregnancy and compared those mothers who had taken folic acid to those who hadn’t taken any folic acid.”

VIDEO

GXF FULL JAMA COVER

AUDIO

VO

THE STUDY APPEARS IN JAMA, JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION.

AUDIO

SOT/FULL Super @1:18 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:10

“The women who took folic acid supplements in early pregnancy had a substantial reduction in risk of having a child with autism, the reduction was 40 percent.”

(Video covering 1st half of bite: folic acid pills)

AUDIO

SOT/FULL Super @1:29 Ezra Susser, M.D., Dr. P.H., – Mailman School of Public Health, Columbia University Runs:17

“There’s a sensitive period in which folic acid supplements need to be taken in order to reduce the risk of autism the period begins before pregnancy and continues approximately two months after pregnancy.”

(Video covering 2nd half of bite: pregnant women’s stomach, pregnant women getting ultrasound)

VIDEO

B-ROLL

Folic acid pills, pregnant stomach, pre-natal vitamins

AUDIO

VO

ALSO, MOTHERS WHO BEGAN TAKING THE SUPPLEMENT AT 22 WEEKS OR MID PREGNANCY COMPARED TO THOSE WHO DID NOT TAKE IT AT THAT TIME SHOWED NO ASSOCIATION WITH A LOWER RISK OF AUTISM. THE SAME WAS TRUE WITH WOMEN WHO TOOK FISH OIL SUPPLEMENTS.

AUDIO

SOT/FULL Super @1:57 P̴l Sur̩n, M.D., M.P.H., РNorwegian Institute of Public Health Runs:08

“This provides an additional reason to take folic acid supplements and it underlines the importance of starting early before the pregnancy has started.”

(Video covering 2nd half of bite: mothers and kids walking)

B-ROLL

Folic acid pills

AUDIO

VO

CATHERINE DOLF, THE JAMA REPORT.

TAG:: RESEARCHERS SAY ALTHOUGH THE STUDY OUTCOME IS STRONG IT IS NOT CONCLUSIVE AND REQUIRES MORE INVESTIGATION.